Upstate New York Vacations from $646

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Your Upstate New York Vacation

Leave all the planning to us with a Upstate New York vacation package. With everything arranged before you depart, all you'll have to do is sit back, chill out and enjoy this destination's wonders to the fullest. With so much to explore on a trip to Upstate New York, it can be difficult to know where to start. Kick off your travels in Buffalo at Walden Galleria Mall and Highmark Stadium — two much-loved attractions here. Another great city to add to your itinerary is Rochester. Be sure not to miss Strong and Seabreeze Amusement Park. Expedia is your one-stop shop when it comes to planning your Upstate New York vacation. From hotels and flights, to car rentals and more, we know how to curate a travel experience like no other.

The Latest Upstate New York Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Night Hotel Broadway
1 Hotel Brooklyn Bridge
The Manner, The Unbound Collection by Hyatt
Ruschmeyers Hotel
Park Lane New York

Where to stay in Upstate New York

Find the best Upstate New York areas and neighborhoods for the activities you enjoy most. Learn more about Upstate New York

Find the Best Upstate New York Vacation Packages

Upstate New York Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Buffalo Niagara Intl. Airport (BUF)

Upstate New York Hotel Deals

Seneca Niagara Resort & Casino
Seneca Niagara Resort & Casino
4 out of 5
310 4th St, Niagara Falls, NY
$176 nightly
The price is $176 total per night from Jun 24 to Jun 25
$176 total
Jun 24 - Jun 25
Total includes taxes and fees
8.6/10 Excellent! (3,341 reviews)
"The view from the upper floors is spectacular. On a clear day you can see straight to Canada 🍁"

Reviewed on Jun 11, 2025

Seneca Niagara Resort & Casino
Buffalo Airport Hotel
Buffalo Airport Hotel
3 out of 5
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $133 total per night from Jun 24 to Jun 25
$133 total
Jun 24 - Jun 25
Total includes taxes and fees
8/10 Very Good! (2,492 reviews)
"My wife and i had a great time and the staff was very kind and considerate. They was very helpful. We will be staying there in thefuture"

Reviewed on Jun 11, 2025

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
2.5 out of 5
100 Holtz Dr, Buffalo, NY
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $98 total per night from Jun 18 to Jun 19
$98 total
Jun 18 - Jun 19
Total includes taxes and fees
7.8/10 Good! (1,594 reviews)
"Staff was friendly and helpful the room was clean"

Reviewed on Jun 12, 2025

Sleep Inn & Suites Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Upstate New York

What to do in Upstate New York

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.