Wesco Vacation Rentals

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Vacation Rentals in Wesco

Relax in the Ozark woods at a quiet nature retreat with a private walking trail.

10.0 out of 10, Exceptional, (22)
"We had a very relaxing time and really enjoyed getting to spend some time around the firepit"
$143 nightly
The price is $152
Oct 2 - Oct 3
Total with taxes and fees
Relax in the Ozark woods at a quiet nature retreat with a private walking trail.

Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River

9.4 out of 10, Exceptional, (141)
"We enjoyed our stay, but the cleanliness of the outside and inside should have been better. We didn’t use the hot tub because it wasn’t clean. The host did offer to clean it. Also need to update with current pictures online."
Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River

Escape to PARADISE on 10 sprawling acres in which to do anything you please!

9.8 out of 10, Exceptional, (29)
"Stay was great and host was extremely helpful, grear views and amenities. Would stay again"
$299 nightly
The price is $299
Oct 23 - Oct 24
Total with taxes and fees
Escape to PARADISE on 10 sprawling acres in which to do anything you please!

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

10.0 out of 10, Exceptional, (17)
"We really enjoyed our stay, house had everything we needed! Beautiful place! "
$191 nightly
The price is $194
Oct 6 - Oct 7
Total with taxes and fees
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub

9.6 out of 10, Exceptional, (299)
"Nice little cabin, would stay again."
Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub

The James Stay on Historic Route 66, minutes away from Wineries & Restaurants

9.6 out of 10, Exceptional, (18)
"This home was perfect for our family when we came to visit our granddaughter in St James. The home was very clean and quiet. We really enjoyed our stay. "
$195 nightly
The price is $195
Oct 7 - Oct 8
Total with taxes and fees
The James Stay on Historic Route 66, minutes away from Wineries & Restaurants

Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

10.0 out of 10, Exceptional, (45)
"Property was very nice ..great location for what we did..I loved the deck on the back with easy parking "
$168 nightly
The price is $168
Oct 6 - Oct 7
Total with taxes and fees
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Private River Frontage!!! Beautiful Cabin with Amazing views! Available now!!

10.0 out of 10, Exceptional, (139)
"Beautiful property and cozy cabin. We had a wonderful stay and would definitely stay again! "
Private River Frontage!!! Beautiful Cabin with Amazing views! Available now!!

Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River

9.8 out of 10, Exceptional, (273)
"I was very impressed on how nice this cabin was. Its a great deal if you stay in the area. I would highly recommend!"
Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River

Three Rivers Retreat in Steelville, MO. 2 Bedroom Cabin on 20 Acres

9.2 out of 10, Wonderful, (36)
"We will be back. No complaints! "
$277 nightly
The price is $277
Oct 2 - Oct 3
Total with taxes and fees
Three Rivers Retreat in Steelville, MO. 2 Bedroom Cabin on 20 Acres

Peaceful Cottage & Beautiful views! River Access. Newly renovated.

10.0 out of 10, Exceptional, (46)
"Viola’s Cottage was the perfect place for our family to stay. Beautiful grounds and the house had everything we needed. We have a new grandson and staying here will now be part of our annual family gathering. "
Peaceful Cottage & Beautiful views! River Access. Newly renovated.

Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets

10.0 out of 10, Exceptional, (299)
"Most relaxing place i have been to in awhile"
Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets

Get Back to Nature at Three Pine Cabin

9.8 out of 10, Exceptional, (289)
"It was great place to stay for the family float trip! Thank you!"
Get Back to Nature at Three Pine Cabin

Townside Blue House

9.2 out of 10, Wonderful, (25)
"Only stayed for one night, worked for my needs"
$169 nightly
The price is $176
Oct 2 - Oct 3
Total with taxes and fees
Townside Blue House

Peaceful and quiet cabin with keypad entry for convenient self check in.

10.0 out of 10, Exceptional, (86)
"Amazing little cabin for a perfect getaway. "
$145 nightly
The price is $145
Oct 5 - Oct 6
Total with taxes and fees
Peaceful and quiet cabin with keypad entry for convenient self check in.

1910 on Route 66 is a Charming historic 2 bedroom 2 bath home, close to downtown

2.0 star property
9.8 out of 10, Exceptional, (15)
"Beautiful house, old charm, came to town for sons graduation from Missouri S&T. Home was well maintained and easy to get too we loved it, we are planning on going back again sometime just to relax."
1910 on Route 66 is a Charming historic 2 bedroom 2 bath home, close to downtown

Private Meramec River Frontage!! Cozy Cabin with River views and access!!

10.0 out of 10, Exceptional, (21)
"This place was awesome. Will definitely try to stay there again "
Private Meramec River Frontage!! Cozy Cabin with River views and access!!

Changing leaves at Patten's Landing, our 83-year old restored river cabin!

10.0 out of 10, Exceptional, (22)
"Our stay was phenomenal. They put so much thought into everything to make this a great vacation. Property was amazing and river access put it over top."
Changing leaves at Patten's Landing, our 83-year old restored river cabin!

Townside White House

10.0 out of 10, Exceptional, (7)
"We really enjoyed our stay. The house is beautiful and has a great layout. The dogs enjoyed the fenced in backyard. Perfect location to Rolla. Highly recommend. "
$180 nightly
The price is $180
Oct 6 - Oct 7
Total with taxes and fees
Townside White House

Hawks Ridge Cabin

9.8 out of 10, Exceptional, (81)
"A beautiful place to stay"
Hawks Ridge Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Wesco Hotel Reviews

Find out more about Wesco

Find out more about Wesco

Everything you need to know about Wesco vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Wesco vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Wesco vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Wesco vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Wesco. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Wesco in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $145 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Wesco rentals

At Expedia, we put the best Wesco vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Wesco rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Wesco vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Wesco. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Wesco?

Yes, we give you a choice of vacation rentals near popular local attractions in Wesco, or you can go with a more secluded option if you'd like a relaxing place to stay.

What's the top vacation rental that Wesco has to offer?

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James : This vacation home rental near Wesco offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

What can I see and do in Wesco?

While you're exploring the area, Meramec River and Maramec Spring Park are a couple of picturesque spots to get outside and enjoy nature. Peaceful Bend Vineyard and Fanning Route 66 Outpost are a couple of places you'll find in the larger area.

What are vacation rentals like in Wesco?

Vacation rentals are private properties you can book for several days or longer in Wesco. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive option for a family trip.