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Our top choices for Advance hotels

A living room with a blue wall, a fireplace, a sofa, and a chair.
A brick building with a sign reading "Mercantile & Hotel".
A bar area with stools and a counter where a bartender is serving drinks.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

1. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
$87 nightly
$94 total
Sep 4 - Sep 5
Total with taxes and fees
EC Reed's Mercantile and Hotel
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
$100 nightly
$113 total
Sep 6 - Sep 7
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

3. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
Canada
Raidas
$72 nightly
$81 total
Sep 6 - Sep 7
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A hotel room with two beds, a nightstand, a lamp, and a chair.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Shawn
$93 nightly
$100 total
Sep 1 - Sep 2
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.
A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

5. Dexter Inn

Dexter Inn
Dexter
United States
Edward
$58 nightly
$65 total
Sep 1 - Sep 2
Total with taxes and fees
Dexter Inn
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A restaurant with a brick wall, a flat-screen TV, and a bar area.

6. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Jamie
$83 nightly
$88 total
Sep 21 - Sep 22
Total with taxes and fees
Drury Inn & Suites Jackson MO
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

7. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
$98 nightly
$110 total
Sep 7 - Sep 8
Total with taxes and fees
Hampton Inn By Hilton Dexter
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
Canada
Chevonne
$101 nightly
$114 total
Sep 6 - Sep 7
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.
A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.
A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.
A bathroom with a bathtub, toilet, and a shower curtain.

9. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
Tammy
$61 nightly
$67 total
Sep 1 - Sep 2
Total with taxes and fees
OYO Hickory House Inn
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A multi-story hotel with a mix of brick and red facade, featuring a Holiday Inn Express sign.

10. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
$105 nightly
$118 total
Sep 6 - Sep 7
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern retail area with a display of local items and snacks.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

11. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Darlene
$89 nightly
$102 total
Sep 7 - Sep 8
Total with taxes and fees
Tru By Hilton Cape Girardeau
A diner with booth seating, a checkered floor, and a counter with a cash register.
A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.
A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.
A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

12. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
$92 nightly
$103 total
Sep 10 - Sep 11
Total with taxes and fees
Travelodge by Wyndham Dexter
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

13. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
$106 nightly
$119 total
Sep 7 - Sep 8
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East
A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.
A hotel reception area with a reception desk, framed certificates, and a painting on the wall.
A hotel with a brick facade, multiple windows, and a covered entrance area.
A living room with a sofa, a coffee table, a clock, and a painting on the wall.

14. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
$49 nightly
$55 total
Sep 30 - Oct 1
Total with taxes and fees
Econo Lodge Dexter
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

15. Town House Inn

Town House Inn
Jackson
United States
Taylor
$78 nightly
$84 total
Sep 1 - Sep 2
Total with taxes and fees
Town House Inn
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

16. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Cheryl
$90 nightly
$102 total
Sep 6 - Sep 7
Total with taxes and fees
Drury Inn & Suites Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

17. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
$62 nightly
$70 total
Sep 7 - Sep 8
Total with taxes and fees
Quality Inn Cape Girardeau North
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

18. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
$101 nightly
$114 total
Sep 13 - Sep 14
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.

19. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
$80 nightly
$86 total
Sep 21 - Sep 22
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

20. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
$105 nightly
$119 total
Sep 20 - Sep 21
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
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Top Advance Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"Will definitely stay again. Very comfortable beds"
Carla Jo 2-night trip
Posted less than an hour ago
Candlewood Suites Cape Girardeau by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"Nice customer service. I liked the access to washer and dryer, as well as cookies being served in the evening. I like the indoor pool and the gym. Is closed to many restaurants and showing mall."
Elvira 3-night trip
Posted 12 hours ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent
"The room was beautiful and had everything needed!! So clean!"
Tammy 1-night trip
Posted 14 hours ago
Fairfield Inn & Suites by Marriott Cape Girardeau
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Very clean and very nice"
Eric 1-night trip
Posted 15 hours ago
Hampton Inn Sikeston
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

8/10 Good
"Staff was friendly and welcoming."
Darlene 1-night trip
Posted 5 days ago
Tru By Hilton Cape Girardeau
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"Best Hampton Inn that I have ever stayed in. Excellent service and Wonderful staff. Extremely helpful with disabled husband."
Stephen 2-night trip
Posted 11 days ago
Hampton Inn By Hilton Dexter
Charming 3-bedroom house in delightful Advance with AC, WiFi

Charming 3-bedroom house in delightful Advance with AC, WiFi

10/10 Excellent
"Our host was an excellent communicator who took great care of us. The place was immaculate and well cared for. We came back after having been here earlier in the year. 10/10 would recommend!"
Jeremy S. 3-night trip
Posted 1 month ago
Charming 3-bedroom house in delightful Advance with AC, WiFi

More cheap stays in Advance

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
$72 nightly
$81 total
Sep 6 - Sep 7
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO
$89 nightly
$102 total
Sep 7 - Sep 8
Total with taxes and fees
9.6/10 Exceptional! (173 reviews)
Tru By Hilton Cape Girardeau
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO
$89 nightly
$106 total
Sep 13 - Sep 14
Total with taxes and fees
8/10 Very Good! (999 reviews)
Candlewood Suites Cape Girardeau by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
$102 nightly
$115 total
Sep 13 - Sep 14
Total with taxes and fees
9/10 Wonderful! (618 reviews)
Hampton Inn Sikeston
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
$105 nightly
$118 total
Sep 6 - Sep 7
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO
$105 nightly
$119 total
Sep 20 - Sep 21
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Hotels in Advance with star-rating

Frequently asked questions

What is the best area to stay in Advance?
Given the size and nature of Advance, Missouri, the best area to stay is generally within the town limits, focusing on accommodations that offer convenient access to local amenities and the main thoroughfares.Advance is a small, rural town, and visitors typically prioritize convenience and practicality. Staying near Highway 25 or Highway 91 puts you close to the few local businesses, including gas stations and small eateries. This central area allows for easy navigation whether you're visiting for local events, family, or as a stopover.Travelers looking for a quiet, straightforward stay will find the general area of Advance suitable. Accommodations here are usually no-frills, providing a comfortable place to rest.
When is the best time to go to Advance?
The best times to visit Advance, Missouri, are during the spring (April to May) and fall (September to October) when the weather is most pleasant.During these months, you'll experience mild temperatures, making it comfortable for outdoor activities like exploring local parks or attending community events. Spring brings blooming dogwoods and redbuds, while fall offers scenic foliage as the leaves change color.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Advance.
How much is the nightly rate at a Advance hotel?
Prices for hotels in Advance often vary, but you can find a great deal from $65 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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