The Best Hotels Closest to Biomuseo in Panama City for 2026

A modern building with colorful geometric shapes and a clear blue sky.

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Our top choices for Biomuseo hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A room with a large window, a television mounted on the wall, and two chairs.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

1. La Isabela Suites

San Felipe, 1.5 mi from Biomuseo

David

$135 nightly

$151 total

Oct 5 - Oct 6

Total with taxes and fees

A restaurant with multiple dining tables, chairs, and a central water feature.

A historic building with ornate stonework and a balcony with plants.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A bar area with multiple seating options, a bar counter, and a fireplace.

2. Hotel La Compañía Casco Antiguo

San Felipe, 1.5 mi from Biomuseo

Reid

$280 nightly

$308 total

Sep 29 - Sep 30

Total with taxes and fees

A multi-story building with ornate balconies, large windows, and decorative moldings.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

3. Hotel Plaza Herrera

San Felipe, 1.5 mi from Biomuseo

Christina

$178 nightly

$198 total

Oct 18 - Oct 19

Total with taxes and fees

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

A hotel with a rooftop pool, lounge chairs, and a view of the sea.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

4. Sofitel Legend Casco Viejo, Panama City

San Felipe, 1.6 mi from Biomuseo

Jose

$396 nightly

$436 total

Oct 6 - Oct 7

Total with taxes and fees

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

A glass of white wine on a balcony railing overlooking a city street with buildings and cars.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

5. La Concordia Boutique Hotel

San Felipe, 1.5 mi from Biomuseo

Jadah

$202 nightly

$222 total

Oct 8 - Oct 9

Total with taxes and fees

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

6. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 1.6 mi from Biomuseo

Shanae

$236 nightly

$260 total

Sep 30 - Oct 1

Total with taxes and fees

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

7. Hotel San Felipe

San Felipe, 1.5 mi from Biomuseo

Rebecca

$141 nightly

$155 total

Oct 1 - Oct 2

Total with taxes and fees

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A spacious lobby with a tiled floor, large windows, and potted plants.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

A white building with multiple balconies, large windows, and decorative railings.

8. American Trade Hotel

San Felipe, 1.5 mi from Biomuseo

Caroline

$163 nightly

$181 total

Oct 13 - Oct 14

Total with taxes and fees

A multi-story building with balconies, large windows, and a clear blue sky.

An outdoor patio with a white umbrella, lounge chairs, and a tiled floor.

A hotel room with a brick wall, a large window with curtains, a bed with pillows, a nightstand, and a chair.

A hallway with a brick wall, a blue door, and a chair with a cushion.

9. Las Clementinas

San Felipe, 1.6 mi from Biomuseo

James

$170 nightly

$187 total

Oct 13 - Oct 14

Total with taxes and fees

A multi-story building with balconies, arched windows, and decorative railings.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A building with a balcony and a street view.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

10. Central Hotel Panama Casco Viejo

San Felipe, 1.5 mi from Biomuseo

Olga

$190 nightly

$209 total

Sep 29 - Sep 30

Total with taxes and fees

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

11. Hotel Magnolia Boutique

San Felipe, 1.5 mi from Biomuseo

Boris

$70 nightly

$77 total

Sep 30 - Oct 1

Total with taxes and fees

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

A modern kitchen with a large window, a dining area with chairs, and a view of the city.

12. Casco View Life Residences

Santa Ana, 1.5 mi from Biomuseo

Ruben

$105 nightly

$116 total

Oct 8 - Oct 9

Total with taxes and fees

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

13. Tantalo Hotel

San Felipe, 1.6 mi from Biomuseo

Cassondra

$68 nightly

$76 total

Oct 4 - Oct 5

Total with taxes and fees

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A living room with a patterned sofa, a matching ottoman, a large mirror, and a staircase leading to an outdoor area.

14. Hotel Bardot Boutique

San Felipe, 1.6 mi from Biomuseo

Gary

$80 nightly

$88 total

Oct 4 - Oct 5

Total with taxes and fees

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A garden with a concrete pathway, various plants, and a birdcage.

A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.

A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

15. The Balboa Inn

Balboa, 1.7 mi from Biomuseo

Rhonda

$63 nightly

$70 total

Oct 4 - Oct 5

Total with taxes and fees

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

A formal dining area with round tables, white tablecloths, and blue lace borders.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

16. Radisson Hotel Panama Canal

Amador, 0.9 mi from Biomuseo

Samantha

$78 nightly

$86 total

Sep 30 - Oct 1

Total with taxes and fees

A poolside area with white sofas, a pool, and outdoor seating.

A modern bedroom with a large bed, bedside lamps, a flat-screen TV, and a wall-mounted air conditioner.

A modern living room with a flat-screen TV mounted on a wooden wall unit, a door leading to a kitchen area, and a dining table with bar stools.

17. La Palma Experience

Amador, 0.7 mi from Biomuseo

Juan Luis Perez

$75 nightly

$83 total

Sep 29 - Sep 30

Total with taxes and fees

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

A compact kitchen with a dining area, including a coffee maker, sink, and wooden chairs.

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

18. Corcho

San Felipe, 1.5 mi from Biomuseo

Ashley

$82 nightly

$90 total

Sep 29 - Sep 30

Total with taxes and fees

A modern kitchen with a dining area, large windows, and a view of the city.

A modern restaurant with a sushi bar, bar seating, and a mix of indoor and outdoor dining areas.

A modern kitchen with a built-in oven and microwave, a living area with a sofa and ottomans, and a stone wall with a television.

A modern kitchen with a built-in island, stainless steel appliances, and black bar stools.

19. La Cuadra by Wynwood House

El Chorrillo, 1.4 mi from Biomuseo

Lise Jane

$171 nightly

$185 total

Oct 4 - Oct 5

Total with taxes and fees

A modern living room with a dining area, a sofa, and a round mirror on the wall.

A modern kitchen with white cabinets, a black induction cooktop, and a coffee maker.

A spacious room with a dining table, chairs, a sofa, and a large window.

A modern living room with a large flat-screen TV, a blue sofa, and a dining area in the background.

20. Casa Love by Wynwood House

San Felipe, 1.4 mi from Biomuseo

Margarita Gricelda Hurtado

$88 nightly

$97 total

Oct 1 - Oct 2

Total with taxes and fees

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Compare popular hotels close to Biomuseo

Property	Star rating	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 354 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 49 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 751 reviews	View
La Concordia Boutique Hotel	9.6 Exceptional 237 reviews	View

Top Biomuseo Hotel Reviews

Hotel La Compañía Casco Antiguo

10/10 Excellent

"It was a romantic outing for me and my loved one, we had a nice Spa treatment then a wonderful dinner experience at the hotels special restaurant Villa Ana and its rooftop bar Atico. Breakfast was very nice! Wonderful stay!"

Hotel Magnolia Boutique

8/10 Good

"The room was clean bed comfy the front staff wad exceptional very friendly an very helpful cant say enough about the front desk staff they made the stay great I would definitely stay here again my one suggestion would be a small refrigator in the room an a lock box my friend room had lock box mine didn't had to share his other than that great spot right in the middle of everything"

American Trade Hotel

8/10 Good

"Nice hotel and beautiful room with terrace facing the square. Difficulty entering the room halfway through my one night stay which involved several trips to the reception after being told the batteries in the door needed changing. Should really have been sorted at maintenance. Communication between staff not great as despite being allowed a late checkout, cleaning staff came repeatedly banging on the door in that last hour."

Hotel Caracas - Casco Viejo

10/10 Excellent

"We stayed one night there. Very comfortable location. The room was clean, nice shower, helpful and friendly staff, and they have good coffee in the lobby :)"

Hotel San Felipe

10/10 Excellent

"This property is set in a great location and is very cute and clean. The bed was great. The staff was very nice and efficient without being overwhelming. We didn't eat at the restaurant because we did a lot of exploring but would definitely stay again. The only thing I would say needs some improvement is the wifi strength it wasn't always reliable."

La Palma Experience

10/10 Excellent

"I would recommend this hotel. It has a great location and offers a very pleasant experience."

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

"Sofitel Legend is a wonderful place to stay. The staff are amazing."

Hotel Casa Panamá

8/10 Good

"Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance."

La Concordia Boutique Hotel

10/10 Excellent

"Location was excellent, in the thick of things in Casco Viejo and walking distance to a wide variety of shops and restaurants. The rooftop restaurant was very nice though we didn’t eat there. Our room was large, with a huge bathroom, huge shower, and double sinks. Decor was wonderful. Highly recommended."

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

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Amador Convention Center

9.2/10 (23 reviews)

Learn about the events happening at Amador Convention Center during your trip to Ancon. While in this walkable area, you can savor the top-notch restaurants.

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Punta Culebra Nature Center

9.0/10 (14 reviews)

Enjoy an outing to Punta Culebra Nature Center during your stay in Ancon. Stroll along the seaside in this vibrant area, or check out its top-notch restaurants.

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Maracana Stadium

8.0/10 (32 reviews)

Catch an event at Maracana Stadium during your trip to Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Smithsonian Tropical Research Institute Punta Culebra

9.2/10 (19 reviews)

You can spend time browsing the exhibits at Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

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Danilo Perez Foundation

Explore the campus of Danilo Perez Foundation as part of your travels around Panama City. Check out the shops and top-notch restaurants in this vibrant area.

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Plaza de Francia

10.0/10 (1 review)

You can learn about the history of Panama City when you stop by Plaza de Francia. Check out the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time browsing the exhibits at Mola Museum during your trip to Panama City. You can enjoy the bars while in the area.

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Frequently asked questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1261 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels will I be able to find near Biomuseo?

Expedia has 1261 hotels and other accommodations a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near Biomuseo.

Where can I learn more about changing or cancelling my trip in the area near Biomuseo?

For more information about updating your stay near Biomuseo or cancelling it, click here.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum, and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen, and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at National Theater, Anita Villalaz Theater, and Amador Theater.

Find hotels near Biomuseo, Panama City from $70

Upfront pricing

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Biomuseo hotels

1. La Isabela Suites

2. Hotel La Compañía Casco Antiguo

3. Hotel Plaza Herrera

4. Sofitel Legend Casco Viejo, Panama City

5. La Concordia Boutique Hotel

6. Amarla Boutique Hotel Casco Viejo Adults Only

7. Hotel San Felipe

8. American Trade Hotel

9. Las Clementinas

10. Central Hotel Panama Casco Viejo

11. Hotel Magnolia Boutique

12. Casco View Life Residences

13. Tantalo Hotel

14. Hotel Bardot Boutique

15. The Balboa Inn

16. Radisson Hotel Panama Canal

17. La Palma Experience

18. Corcho

19. La Cuadra by Wynwood House

20. Casa Love by Wynwood House

Compare popular hotels close to Biomuseo

Top Biomuseo Hotel Reviews

Hotel La Compañía Casco Antiguo

Hotel Magnolia Boutique

American Trade Hotel

Hotel Caracas - Casco Viejo

Hotel San Felipe

La Palma Experience

Sofitel Legend Casco Viejo, Panama City

Hotel Casa Panamá

La Concordia Boutique Hotel

Other attractions near Biomuseo

Amador Causeway

Amador Convention Center

Punta Culebra Nature Center

Maracana Stadium

Smithsonian Tropical Research Institute Punta Culebra

Danilo Perez Foundation

Plaza de Francia

Mola Museum

Frequently asked questions