---
title: "Top 10 Hotels in Centerville, SC (from $53) 2026 - Competitive Prices | Expedia"
description: "Find 570 of the best hotels in Centerville, SC in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable."
canonical: "https://www.expedia.com/Centerville-Hotels.d553248634999313202.Travel-Guide-Hotels"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-14T07:45:33Z
---

Plan your trip

- [Centerville Travel Guide](https://www.expedia.com/Centerville.dx553248634999313202)
- [Flights to Centerville](https://www.expedia.com/Cheap-Flights-To-Centerville.d553248634999313202.Travel-Guide-Flights)
- [Car Rentals in Centerville](https://www.expedia.com/Car-Rentals-In-Centerville.d553248634999313202.Car-Rental-Guide)
- [Centerville Vacation Packages](https://www.expedia.com/Centerville.d553248634999313202.Destination-Travel-Guides)
- [Vacation Rentals in Centerville](https://www.expedia.com/Centerville-Vacation-Rentals.d553248634999313202.Travel-Guide-VacationRentals)

# Find hotels in Centerville, SC from $53

### Upfront pricing
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## Go beyond your typical stay in Centerville

[Pet friendly](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=PETS)

[Hot tub](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=HOT%5FTUB)

[Pool](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=POOL)

[Cabin](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=CABIN)

[Family friendly](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&travelerType=family%5Ffriendly)

[Apart hotel](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=APART%5FHOTEL)

[Apart­ment](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=APARTMENT)

[Campsite](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=CARAVAN%5FPARK)

[Condo](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=CONDO)

[Cottage](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=COTTAGE)

[Villa](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=VILLA)

[Waterpark](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&amenities=WATER%5FPARK)

[Farm](https://www.expedia.com/Hotel-Search?destination=Centerville,%20South%20Carolina,%20United%20States%20of%20America&regionId=553248634999313202&latLong=34.532051,-82.704025&adults=2&startDate=2026-11-21&d1=2026-11-21&endDate=2026-11-23&d2=2026-11-23&lodging=AGRITOURISM)

## Check prices for these dates

[Check prices for these dates, December 14 – 15, 2026](https://www.expedia.com/Hotel-Search?regionId=553248634999313202&startDate=2026-12-14&endDate=2026-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

[View in a map](https://www.expedia.com/Hotel-Search?regionId=553248634999313202&stayLength=1&daysInFuture=30&pwaOverlay=map)

## Our top choices for Centerville hotels

### [1\. Embassy Suites Greenville Golf Resort & Conference Center](https://www.expedia.com/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![A multi-level hotel lobby with a central atrium, multiple dining areas, and a reception desk.](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/cf0193a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: Greenville
- Guest rating: 9/10 (Wonderful, 1481 reviews)
- Price: $108 nightly, $120 total, Nov 23 - Nov 24, Total with taxes and fees
- Review: The afternoon reception was great. The breakfast was the best ever., by JUDY, 2 days ago

### [2\. Hilton Greenville](https://www.expedia.com/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information)

![A spacious lobby with modern furniture, a chandelier, and potted plants.](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville
- Guest rating: 8.4/10 (Very good, 1041 reviews)
- Price: $100 nightly, $110 total, Dec 12 - Dec 13, Total with taxes and fees
- Review: Positive is the staff is very good and the restaurant is excellent., by gloria, 5 days ago

### [3\. Days Inn by Wyndham Anderson](https://www.expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information)

![A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a large window with a view of trees.](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/2c664569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 8/10 (Very good, 1031 reviews)
- Price: $59 nightly, $65 total, Nov 24 - Nov 25, Total with taxes and fees
- Review: Good for family s had a pull out couch and 2 queens., by nzinga, 12 days ago

### [4\. Grand Bohemian Lodge Greenville, Autograph Collection](https://www.expedia.com/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information)

![A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 9.6/10 (Exceptional, 570 reviews)
- Price: $277 nightly, $305 total, Nov 29 - Nov 30, Total with taxes and fees
- Review: Staff was helpful. The room was very clean., by ALICE, September 30th, 2026

### [5\. Hyatt Regency Greenville](https://www.expedia.com/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information)

![A spacious lobby with a central bar area, multiple seating options, and a distinctive ceiling structure.](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/2e6ff142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 8.6/10 (Excellent, 1002 reviews)
- Price: $141 nightly, $155 total, Nov 23 - Nov 24, Total with taxes and fees
- Review: Loved the location. Got to room had 3 towels., by Deborah, 18 days ago

### [6\. Drury Inn & Suites Greenville](https://www.expedia.com/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information)

![A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/5e60bd70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville
- Guest rating: 9.4/10 (Exceptional, 1096 reviews)
- Price: $115 nightly, $126 total, Nov 23 - Nov 24, Total with taxes and fees
- Review: Excellent stay as usual. Staff was friendly as always. Breakfast buffet were great., by Ashley, 11 days ago

### [7\. Holiday Inn Anderson by IHG](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Anderson.h5385.Hotel-Information)

![A spacious living area with a sofa, two armchairs, a coffee table, and a chandelier. Large windows provide a view of the outdoors.](https://images.trvl-media.com/lodging/1000000/10000/5400/5385/dec5857a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 8.8/10 (Excellent, 779 reviews)
- Price: $106 nightly, $118 total, Dec 13 - Dec 14, Total with taxes and fees
- Review: It was a very nice stay., by Melissa, 7 days ago

### [8\. Hilton Garden Inn Anderson](https://www.expedia.com/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information)

![A hotel lobby with a reception desk, potted plants, and a tiled floor.](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9/10 (Wonderful, 795 reviews)
- Price: $95 nightly, $106 total, Dec 4 - Dec 5, Total with taxes and fees
- Review: The staff were very helpful and friendly., by Valerie, October 13th, 2026

### [9\. Homewood Suites by Hilton Greenville Downtown](https://www.expedia.com/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information)

![A covered outdoor area with a grill and seating, surrounded by brick walls and windows.](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/5ad65bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 9.6/10 (Exceptional, 1002 reviews)
- Price: $138 nightly, $151 total, Nov 24 - Nov 25, Total with taxes and fees
- Review: The staff here are top notch., by Jessica, 4 days ago

### [10\. Best Western Plus Greenville I-385 Inn & Suites](https://www.expedia.com/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![A modern kitchen with a stone backsplash, a built-in coffee station, and a dining area with a round wooden table and chairs.](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville
- Guest rating: 9.2/10 (Wonderful, 1613 reviews)
- Price: $75 nightly, $83 total, Dec 6 - Dec 7, Total with taxes and fees
- Review: Staff was very efficient. Breakfast was great. Having parking was easy., by robert, 6 days ago

### [11\. Home2 Suites by Hilton Anderson Downtown](https://www.expedia.com/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information)

![A modern kitchen with a central island, bar stools, and a dining area with a sofa and chairs.](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/284160fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9.4/10 (Exceptional, 273 reviews)
- Price: $140 nightly, $155 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Breakfast options included healthy food choices. We really enjoyed our stay., by John, October 8th, 2026

### [12\. Hyatt Place Greenville Downtown](https://www.expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information)

![A modern hotel building with a flat roof and a sign reading "HYATT PLACE".](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/585ae4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 9.2/10 (Wonderful, 1004 reviews)
- Price: $131 nightly, $144 total, Nov 29 - Nov 30, Total with taxes and fees
- Review: Clean and spacious rooms. Welcoming staff. Great location., by Leah, 14 days ago

### [13\. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://www.expedia.com/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information)

![A spacious hotel lobby with a reception desk, seating area, and a large plant.](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/dc36b448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville
- Guest rating: 8.6/10 (Excellent, 1004 reviews)
- Price: $97 nightly, $107 total, Nov 23 - Nov 24, Total with taxes and fees
- Review: Conveniently located near downtown Greenville. The hotel was clean. A great place to stay., by Hassan, 14 days ago

### [14\. The Bleckley Inn](https://www.expedia.com/Anderson-Hotels-The-Bleckley-Inn.h4100280.Hotel-Information)

![The Blackley Inn, a brick building with a sign above the entrance.](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100280/554421e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9.8/10 (Exceptional, 431 reviews)
- Price: $195 nightly, $216 total, Dec 14 - Dec 15, Total with taxes and fees
- Review: Great location, nicely maintained property, beautiful rooms and delicious hot breakdast., by Meredith, 13 days ago

### [15\. Microtel Inn & Suites by Wyndham Anderson/Clemson](https://www.expedia.com/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information)

![A multi-story hotel with a central entrance, parking lot, and a flag.](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2e1b44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 8.4/10 (Very good, 1001 reviews)
- Price: $84 nightly, $93 total, Nov 18 - Nov 19, Total with taxes and fees
- Review: Staff was helpful. Location is right off the highway and very easy access., by Julie, 14 days ago

### [16\. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

![A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4a631ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9.2/10 (Wonderful, 681 reviews)
- Price: $103 nightly, $114 total, Dec 13 - Dec 14, Total with taxes and fees
- Review: Very clean lobby area. Beds were comfortable., by Richard, 19 days ago

### [17\. Residence Inn by Marriott Anderson Clemson](https://www.expedia.com/Anderson-Hotels-Residence-Inn-By-Marriott-Anderson-Clemson.h60352079.Hotel-Information)

![A patio area with a round table and chairs, a fire pit, and a building with a stone facade and blue accents.](https://images.trvl-media.com/lodging/61000000/60360000/60352100/60352079/d6eb90c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9.6/10 (Exceptional, 110 reviews)
- Price: $143 nightly, $159 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: It was a great place to stay. The staff was great., by Tina, 18 days ago

### [18\. Aloft by Marriott Greenville Downtown](https://www.expedia.com/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information)

![A modern lounge area with a fireplace, seating, and a neon sign.](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/w3997h2667x0y0-e203724b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 9.2/10 (Wonderful, 1003 reviews)
- Price: $142 nightly, $157 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Had a great bar. What a perfect area for this hotel., by Jacquelin, 8 days ago

### [19\. Embassy Suites by Hilton Greenville Downtown Riverplace](https://www.expedia.com/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information)

![A modern multi-story hotel with a river in front, featuring a glass facade and outdoor seating areas.](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/w5760h3837x0y3-ea7c15e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Greenville Downtown
- Guest rating: 9.2/10 (Wonderful, 1001 reviews)
- Price: $159 nightly, $176 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Breakfast was good. I wore sandals in the shower., by Leanne, 8 days ago

### [20\. Fairfield Inn & Suites by Marriott Anderson Clemson](https://www.expedia.com/Anderson-Hotels-Fairfield-Inn-Suites-By-Marriott-Anderson-Clemson.h794424.Hotel-Information)

![A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/1d8e7ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Guest rating: 9/10 (Wonderful, 604 reviews)
- Price: $98 nightly, $109 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: The staff was very friendly, room was very clean, breakfast outstanding., by jennifer, October 4th, 2026

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://www.expedia.com/Hotel-Search?startDate=2026-11-28&endDate=2026-11-29&regionId=553248634999313202&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Stay near popular Centerville attractions

Discover the charm of Centerville, where outdoor adventures and romantic scenery await. With beautiful parks and serene lakes, this destination is perfect for families and city explorers alike. Experience the best of nature and relaxation in a truly enchanting setting.

![A kayak on calm water with a sunset in the background.](https://images.trvl-media.com/place/553248635056396940/05df6589-b9be-4432-8fc1-03453cec9796.jpg?impolicy=fcrop&w=960&h=640&p=1&q=medium)

Photo by Victoria S

### Lake Hartwell

Rating: 9.2/10 (155 reviews)

Often cited as a favorite among nature lovers, Lake Hartwell offers stunning scenery and a romantic atmosphere perfect for a day of relaxation. Located about 11 miles from Centerville, this picturesque lake invites visitors to enjoy its beach vibes and outdoor activities, making it a great spot for a memorable getaway.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635056396940)

### South Carolina Botanical Gardens
![A white flower with a yellow center surrounded by green leaves.](https://images.trvl-media.com/place/6228711/82908945-4b73-4111-b8d1-eba80f0a0e2d.jpg?impolicy=fcrop&w=960&h=640&p=1&q=medium)

Rating: 9.2/10 (133 reviews)

Perfectly suited for families and those seeking a romantic getaway, the South Carolina Botanical Gardens offers a stunning array of plants and vibrant landscapes. Located about 12 miles from Centerville, this serene oasis provides an ideal backdrop for leisurely strolls and outdoor activities, making it a convenient stop during your visit.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6228711)

### Anderson University

Rating: 8.6/10 (271 reviews)

Set the stage for your exploration of Anderson University, a historic college that exudes cultural vibes. Located about 4 miles from Centerville, this university offers a unique blend of academic heritage and community engagement, making it an inviting stop for visitors. Staying nearby provides easy access to its vibrant atmosphere.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6308387)

### Anderson County Museum

Rating: 7.8/10 (51 reviews)

Ideal for travelers interested in history, the Anderson County Museum offers a rich exploration of local heritage and culture. Located about 3 miles by car from Centerville, this museum invites you to delve into the region's past, making it a convenient stop during your visit.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6308393)

### T. Ed Garrison Arena

Rating: 7.4/10 (3 reviews)

Considered a premier spot for families seeking entertainment, T. Ed Garrison Arena offers a vibrant atmosphere filled with events and activities. Located about 10 miles from Centerville, it provides easy access for visitors. Staying nearby allows you to enjoy a fun-filled experience without hassle.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6228722)

### Tri-County Technical College

Rating: 10.0/10 (2 reviews)

Discover the appeal of Tri-County Technical College, a vibrant hub for prospective students and visitors alike. This modern institution boasts a lively atmosphere, perfect for exploring educational opportunities. Located about 12 miles by car from Centerville, it offers a convenient stop for those looking to experience local college life.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6228737)

### NewSpring Church

Rating: 7.4/10 (47 reviews)

A captivating destination for spiritual seekers, NewSpring Church offers vibrant cultural vibes in a welcoming atmosphere. Located about 6 miles from Centerville, it provides a unique experience filled with community engagement and inspiring services, making it a convenient stop for visitors looking to enrich their journey.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532656690)

### Woodburn

A must-see for history buffs, Woodburn is a historic house that embodies the rich cultural heritage of South Carolina. Located about 11 miles away from Centerville by car, it offers a glimpse into the past while providing a serene atmosphere. Staying nearby allows for easy access to this charming site.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532656700)

## Top Centerville Hotel Reviews

### [Hilton Garden Inn Anderson](https://www.expedia.com/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information)

![A hotel lobby with a reception desk, potted plants, and a tiled floor.](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 115 Destination Blvd, Anderson, SC, 29621-2343, US
- Location: Anderson
- Star rating: 3/5
- Guest rating: 9/10 (795 reviews)
- Review: Wonderful hotel. Complimentary breakfast would put it over the top!, by THOMAS, July 4, 2022, rated 10/10 Excellent

### [Holiday Inn Anderson by IHG](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Anderson.h5385.Hotel-Information)

![A spacious living area with a sofa, two armchairs, a coffee table, and a chandelier. Large windows provide a view of the outdoors.](https://images.trvl-media.com/lodging/1000000/10000/5400/5385/dec5857a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 3509 Clemson Blvd, Anderson, SC, 29621-1312, US
- Location: Anderson
- Star rating: 3/5
- Guest rating: 8.8/10 (779 reviews)
- Review: My friend and I flew up (from FL) for a mini vacation to visit my brother and niece who live nearby, so the hotel location was perfect. Shopping & restaurants all around, many within walking distance. The hotel was beautiful, nice lobby, nice rooms and the staff all friendly and helpful. We had a wonderful stay and I would most definitely stay here again!, by Donna, October 29, 2016, rated 10/10 Excellent

### [Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

![A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4a631ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 107 Interstate Blvd, Anderson, SC, 29621-2319, US
- Location: Anderson
- Star rating: 2.5/5
- Guest rating: 9.2/10 (681 reviews)
- Review: Lovely hotel. Clean, comfy and everything is expect for the price. Plus free breakfast!, by Ruth, October 27, 2024, rated 10/10 Excellent

### [Days Inn by Wyndham Anderson](https://www.expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information)

![A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a large window with a view of trees.](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/2c664569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 1007 George Smith Mill Rd, Anderson, SC, 29625-5921, US
- Location: Anderson
- Star rating: 2/5
- Guest rating: 8/10 (1031 reviews)
- Review: I like how clean the room and how friendly the staff., by Kianne Niña Keith, April 10, 2025, rated 10/10 Excellent

### [Residence Inn by Marriott Anderson Clemson](https://www.expedia.com/Anderson-Hotels-Residence-Inn-By-Marriott-Anderson-Clemson.h60352079.Hotel-Information)

![A patio area with a round table and chairs, a fire pit, and a building with a stone facade and blue accents.](https://images.trvl-media.com/lodging/61000000/60360000/60352100/60352079/d6eb90c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 109 INTERSTATE BLVD, Anderson, SC, 29621, US
- Location: Anderson
- Star rating: 3/5
- Guest rating: 9.6/10 (110 reviews)
- Review: It was a great place to stay when going to a Clemson football game. The staff was great and the rooms were clean., by Tina, October 26, 2026, rated 10/10 Excellent

### [Country Inn & Suites by Radisson, Anderson, SC](https://www.expedia.com/Anderson-Hotels-Country-Inn-Suites-By-Radisson.h787656.Hotel-Information)

![A kitchen area with blue cabinets, a countertop with various food items, and overhead lighting.](https://images.trvl-media.com/lodging/1000000/790000/787700/787656/5410999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: Everything was great, by Tonya, July 5, 2025, rated 10/10 Excellent

### [Fairfield Inn & Suites by Marriott Anderson Clemson](https://www.expedia.com/Anderson-Hotels-Fairfield-Inn-Suites-By-Marriott-Anderson-Clemson.h794424.Hotel-Information)

![A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/1d8e7ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 117 Interstate Blvd, Anderson, SC, 29621-2319, US
- Location: Anderson
- Star rating: 3/5
- Guest rating: 9/10 (604 reviews)
- Review: This hotel is way better than I thought. Rooms are clean and I can tell by looking at the carpet. Carpet looks brand new on the 2nd floor (that where my room was) No ghettoness around here. It’s located near bunch of restaurants so it’s nice if you are hungry. Room smelled funny when I first walked in but I sprayed some cologne so it’s all good. AC and heat works great. And it’s room is peaceful, nicely decorated Shower pressure is nice and showers tub is clean too!, by Im Rick James, January 21, 2018, rated 10/10 Excellent

### [Hampton Inn Anderson](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Anderson.h248.Hotel-Information)

![A snack display with various packaged snacks and a beverage vending machine in a hotel lobby.](https://images.trvl-media.com/lodging/1000000/10000/300/248/c14dfbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: The hotel is surrounded by good dining, shopping and entertainment options with very close proximity to all that Anderson has to offer., by Kristopher, October 26, 2016, rated 10/10 Excellent

### [Home2 Suites by Hilton Anderson Downtown](https://www.expedia.com/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information)

![A modern kitchen with a central island, bar stools, and a dining area with a sofa and chairs.](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/284160fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 315 S Main St, Anderson, SC, 29621, US
- Location: Anderson
- Star rating: 3/5
- Guest rating: 9.4/10 (273 reviews)
- Review: Very nice hotel and staff., by scott, June 1, 2024, rated 10/10 Excellent

### [Microtel Inn & Suites by Wyndham Anderson/Clemson](https://www.expedia.com/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information)

![A multi-story hotel with a central entrance, parking lot, and a flag.](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2e1b44bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 102 Electric City Blvd, Anderson, SC, 29621-2306, US
- Location: Anderson
- Star rating: 2/5
- Guest rating: 8.4/10 (1001 reviews)
- Review: Loved the size room we got for the price we paid! Easy check in and out. Room was very nice! We will choose this property again., by Judy, June 30, 2024, rated 10/10 Excellent

### [Comfort Suites Anderson-Clemson](https://www.expedia.com/Anderson-Hotels-Comfort-Suites-Anderson-Clemson.h159200.Hotel-Information)

![A reception desk with a marble top, wooden paneling, and pendant lighting.](https://images.trvl-media.com/lodging/1000000/160000/159200/159200/6bbed232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: This hotel is was excellent. It was one of the best hotels I have stayed at and at a reasonable rate. Would highly recommend this hotel., by Arleen, May 2, 2016, rated 10/10 Excellent

### [Rodeway Inn Anderson North - Clemson](https://www.expedia.com/Anderson-Hotels-Rodeway-Inn.h4584724.Hotel-Information)

![A room with a wooden floor, two patterned armchairs, a small table, and a vase with flowers.](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/ebee5c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: Good location., by Anonymous traveler, August 5, 2021, rated 10/10 Excellent

### [The Bleckley Inn](https://www.expedia.com/Anderson-Hotels-The-Bleckley-Inn.h4100280.Hotel-Information)

![The Blackley Inn, a brick building with a sign above the entrance.](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100280/554421e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 151 E Church St, Anderson, SC, 29624, US
- Location: Anderson
- Star rating: 3.5/5
- Guest rating: 9.8/10 (431 reviews)
- Review: Very nice property. Conveniently located in downtown., by Anonymous traveler, February 19, 2020, rated 10/10 Excellent

### [Woodspring Suites Anderson North I-85](https://www.expedia.com/Anderson-Hotels-Woodspring-Suites-Anderson-North-I-85.h114348655.Hotel-Information)

![A modern hotel with a flat roof, multiple floors, and a parking lot.](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/b906225e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: The room is clean, pest free and everything is in working condition. Every equipment in the gym works. The staff is friendly., by Katrina, November 1, 2026, rated 10/10 Excellent

### [The Inn at Patrick Square](https://www.expedia.com/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information)

![A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Clemson
- Review: This was an absolutely beautiful and VERY clean hotel. It is not too far from Clemson University. We will stay here for all of our visits to Clemson., by SHARRA, August 23, 2022, rated 10/10 Excellent

### [Baymont by Wyndham Anderson Clemson](https://www.expedia.com/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information)

![A spacious living room with a desk, computer, and comfortable seating. There are framed paintings on the wall, a large window, and a door leading outside.](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/813e9213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: Staff were exceptional. I will tell my friends that this is a great place to stay at., by Steve, October 3, 2019, rated 10/10 Excellent

### [Hampton Inn Anderson/ Alliance Business Park](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information)

![A spacious dining area with a large table surrounded by chairs, large windows with curtains, and hanging chandeliers.](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/7cf72ddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Anderson
- Review: was very nice polite and breakfast was AWESOME need a room there in august, by Rick, June 25, 2014, rated 10/10 Excellent

### [The Shepherd Hotel Downtown Clemson](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information)

![A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Clemson
- Review: We had an amazing stay. From the beautifully decorated, relaxing room, to the restaurant decor and excellent service and food, to the cute coffee stations on each floor, to the bar and deck, it was all fantastic!, by Amy, July 14, 2025, rated 10/10 Excellent

## Frequently Asked Questions

### What is the best area to stay in Centerville?

The best area to stay in Centerville is the Downtown Historic District, particularly around Main Street and Church Street.

This area is the heart of Centerville, characterized by its well-preserved 19th-century architecture and a collection of local businesses. Main Street is where you'll find most of the independent shops, art galleries, and restaurants, while Church Street is popular for its historic churches and proximity to the Centerville Town Square. It's a very walkable district, making it easy to explore on foot.

Couples often find the Downtown Historic District ideal for a relaxing getaway. The area offers a selection of charming bed and breakfasts, and the evenings provide opportunities for quiet dinners at local restaurants or a stroll through the illuminated Town Square. The Centerville Museum, located just off Main Street, offers insights into the town's past.

For travelers who appreciate convenience and a central location for exploring, the Downtown Historic District is an excellent choice.

### When is the best time to go to Centerville?

The best time to go to Centerville is during the spring (April to June) and fall (September to October) when the weather is mild and comfortable for outdoor activities.

During these seasons, temperatures are pleasant, typically ranging from the low 60s to high 70s Fahrenheit, making it ideal for exploring the town's parks and historical sites without the extreme heat and humidity of summer or the cooler temperatures of winter. Spring brings blooming dogwoods and azaleas, while fall offers colorful foliage, enhancing the natural beauty of the area.

### Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Centerville.

### How much is the nightly rate at a Centerville hotel?

Prices for hotels in Centerville often vary, but you can find a great deal from $53 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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- [Rental cars Anderson County Regional airport](https://www.expedia.com/Car-Rentals-In-Anderson-County-Regional.d6026161.Car-Rental-Guide)
- [Avis Rental Cars in Anderson](https://www.expedia.com/Avis-Car-Rentals-In-Anderson.d6058009-c41.Car-Rental-Guide-Suppliers)
- [Car rental Anderson](https://www.expedia.com/Car-Rentals-In-Anderson.d6058009.Car-Rental-Guide)
- [Enterprise Rental Cars in Anderson County Regional](https://www.expedia.com/Enterprise-Car-Rentals-In-Anderson-County-Regional.d6026161-c15.Car-Rental-Guide-Suppliers)
- [Thrifty Car Rental Rental Cars in Anderson County Regional](https://www.expedia.com/Thrifty-Car-Rental-Car-Rentals-In-Anderson-County-Regional.d6026161-c45.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Anderson County Regional](https://www.expedia.com/Hertz-Car-Rentals-In-Anderson-County-Regional.d6026161-c40.Car-Rental-Guide-Suppliers)
- [Car rental Greenville](https://www.expedia.com/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide)
- [Hertz Rental Cars in Anderson](https://www.expedia.com/Hertz-Car-Rentals-In-Anderson.d6058009-c40.Car-Rental-Guide-Suppliers)
- [Van Car Rentals in Anderson](https://www.expedia.com/Van-Car-Rentals-In-Anderson.d6058009-tVan.Car-Rental-Guide-Class)
- [Rental cars Greenville-Spartanburg Intl. airport](https://www.expedia.com/Car-Rentals-In-Greenville-Spartanburg-Intl.d5264199.Car-Rental-Guide)
- [Car rental Centerville](https://www.expedia.com/Car-Rentals-In-Centerville.d553248634999313202.Car-Rental-Guide)
- [Enterprise Rental Cars in Anderson](https://www.expedia.com/Enterprise-Car-Rentals-In-Anderson.d6058009-c15.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Anderson County Regional](https://www.expedia.com/Budget-Car-Rentals-In-Anderson-County-Regional.d6026161-c39.Car-Rental-Guide-Suppliers)
- [Anderson Vacation Rentals](https://www.expedia.com/Anderson-Vacation-Rentals.d6058009.Travel-Guide-VacationRentals)
- [Things to do in Anderson County](https://www.expedia.com/Things-To-Do-In-Anderson-County.d553248635996998401.Travel-Guide-Activities)

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