Title: Grimes Vacation Rentals from $166: Search Short-Term Rentals | Expedia.com [Grimes Travel Guide](https://expedia.com/Grimes.dx602089)[Hotels in Grimes](https://expedia.com/Grimes-Hotels.d602089.Travel-Guide-Hotels)[Flights to Grimes](https://expedia.com/Cheap-Flights-To-Grimes.d602089.Travel-Guide-Flights)[Car Rentals in Grimes](https://expedia.com/Car-Rentals-In-Grimes.d602089.Car-Rental-Guide)[Grimes Vacation Packages](https://expedia.com/Grimes.d602089.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates In two weeks [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=602089&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=602089&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=602089&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 31 - Aug 2](https://www.expedia.com/Hotel-Search?regionId=602089&startDate=2026-07-31&endDate=2026-08-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Grimes vacation rentals ![Interior](https://images.trvl-media.com/lodging/128000000/127170000/127164900/127164826/eae3a39e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127170000/127164900/127164826/aac6e834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127170000/127164900/127164826/a1ac9a32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127170000/127164900/127164826/ffba3f0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Endless Fun! Family Home w/ Spacious Yard in Clive [](https://www.expedia.com/Des-Moines-Hotels-Endless-Fun-Family-Home-W-Spacious-Yard-In-Clive.h127164826.Hotel-Information) Clive $421 nightly $472 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Endless-Fun-Family-Home-W-Spacious-Yard-In-Clive.h127164826.Hotel-Information) ![Game room](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/ed7a6bcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment, 1 Double Bed with Sofa bed, Non Smoking (Self Check-in with Virtual Front Desk) | In-room dining](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/2fd1c767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 1 King Bed with Sofa bed, Non Smoking (Self Check-in with Virtual Front Desk) | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/f797da5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/fba06a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Downtown Des Moines [](https://www.expedia.com/Des-Moines-Hotels-Kasa-Des-Moines-Downtown-Apartments.h53952761.Hotel-Information) Downtown Des Moines 9.0/10 Wonderful (116 reviews) "The property had the basics of what we needed and worked well for our family. Staff had great communication. Laundry was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jared $160 nightly $179 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Kasa-Des-Moines-Downtown-Apartments.h53952761.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/126000000/125620000/125612600/125612570/74aad456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125620000/125612600/125612570/98b6b793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125620000/125612600/125612570/6f4c70d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125620000/125612600/125612570/65689e5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'the Cove' Polk City Ranch Near Saylorville Lake [](https://www.expedia.com/Des-Moines-Hotels-The-Cove-Polk-City-Ranch-Near-Saylorville-Lake.h125612570.Hotel-Information) Polk City $578 nightly $647 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-The-Cove-Polk-City-Ranch-Near-Saylorville-Lake.h125612570.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23®ionId=602089&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Grimes%2C+Iowa%2C+United+States+of+America®ionId=602089&latLong=41.692285%2C-93.797367&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=VACATION_HOME) Apartments [](https://www.expedia.com/Hotel-Search?destination=Grimes%2C+Iowa%2C+United+States+of+America®ionId=602089&latLong=41.692285%2C-93.797367&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=APARTMENT) Condos [](https://www.expedia.com/Hotel-Search?destination=Grimes%2C+Iowa%2C+United+States+of+America®ionId=602089&latLong=41.692285%2C-93.797367&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=CONDO) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Grimes%2C+Iowa%2C+United+States+of+America®ionId=602089&latLong=41.692285%2C-93.797367&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=APART_HOTEL) Cottages [](https://www.expedia.com/Hotel-Search?destination=Grimes%2C+Iowa%2C+United+States+of+America®ionId=602089&latLong=41.692285%2C-93.797367&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=COTTAGE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGrimes-Vacation-Rentals.d602089.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGrimes-Vacation-Rentals.d602089.Travel-Guide-VacationRentals) ## Top Grimes Hotel Reviews ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/018a0ab2_y.jpg) ### Hyatt Place West Des Moines Jordan Creek 10/10 Excellent "Clean, nice, friendly staff. No complaints" [](https://expedia.com/Des-Moines-Hotels-Hyatt-Place-West-Des-Moines-Jordan-Creek.h16112546.Hotel-Information) ![Ramada Tropics Resort & Conf Center by Wyndham Des Moines](https://images.trvl-media.com/lodging/1000000/10000/1600/1547/b8de3671_y.jpg) ### Ramada Tropics Resort & Conf Center by Wyndham Des Moines 4/10 Poor "Swimming pool water was dirty. Room had soiled walls, rusted light fixtures, missing towel hook, broken mirror on closet door, soiled areas on sofa, vents were rusted & old, tripping hazard out in hallway due to a drain cover that appeared to be homemade & sticking up a good 1/2” from the floor, lobby furniture was worn out." [](https://expedia.com/Des-Moines-Hotels-Ramada-Tropics-Resort-Conf-Center-By-Wyndham-Des-Moines.h1547.Hotel-Information) ![Stoney Creek Hotel Des Moines - Johnston](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/43001d37_y.jpg) ### Stoney Creek Hotel Des Moines - Johnston 10/10 Excellent "Very nice staff" [](https://expedia.com/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) ![Fairfield Inn and Suites by Marriott Des Moines West](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/01d93670_y.jpg) ### Fairfield Inn and Suites by Marriott Des Moines West 10/10 Excellent "Helpful staff. Clean and comfortable room. " [](https://expedia.com/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) ![Quality Inn & Suites Des Moines - Merle Hay Road](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/e0eedf1f_y.jpg) ### Quality Inn & Suites Des Moines - Merle Hay Road 10/10 Excellent "Good motel for the price. " [](https://expedia.com/Des-Moines-Hotels-Quality-Inn-Suites.h9664.Hotel-Information) ![Home2 Suites by Hilton Des Moines at Drake University](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e_y.jpg) ### Home2 Suites by Hilton Des Moines at Drake University 10/10 Excellent "Overall great stay , staff was very accommodating! " [](https://expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/a1ae2959_y.jpg) ### Drury Inn & Suites West Des Moines 10/10 Excellent "First time staying at a Drury. Fantastic experience. Included quality food and drinks in the evening, Great room, comfortable bed, GREAT staff and the breakfast was very good. We will definitely stay here again. Most bang for the buck we’ve seen. " [](https://expedia.com/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![Days Inn & Suites by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/fcd8bd89_y.jpg) ### Days Inn & Suites by Wyndham Des Moines Airport 10/10 Excellent "This hotel is the mid point on our trip. We've stayed here several times and it's always fine." [](https://expedia.com/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Wildwood Lodge](https://images.trvl-media.com/lodging/8000000/7600000/7599000/7598985/dde52107_y.jpg) ### Wildwood Lodge 10/10 Excellent "We had a great stay at Wildwood. The WiFi worked well, the rooms were clean, the pool was fun, the fire pit and fireplace were on and ready for guest, and the staff was helpful and kind. The breakfast had a lot of options (waffles, biscuits and gravy, eggs, cereal, apples, toast, bagels, yogurt, juice) and was what you’d expect for continental breakfast. We would definitely stay there again!" [](https://expedia.com/Des-Moines-Hotels-Wildwood-Lodge.h7598985.Hotel-Information) ## Find out more about Grimes **Everything you need to know about Grimes vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Grimes vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Grimes vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Grimes vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Grimes. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Grimes in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $166 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Grimes rentals** At Expedia, we put the best Grimes vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Grimes rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Grimes vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Grimes. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Grimes ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) - [Vacation Homes in Grimes ](https://expedia.com/Grimes-Private-Vacation-Homes.d602089-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Grimes ](https://expedia.com/Grimes-Apartments.d602089-aaApartments.Travel-Guide-Accommodation) - [Cottages in Grimes ](https://expedia.com/Grimes-Cottages.d602089-aaCottages.Travel-Guide-Accommodation) - [Condo Rentals in Grimes ](https://expedia.com/Grimes-Condos.d602089-aaCondos.Travel-Guide-Accommodation) - [Motels in Grimes ](https://expedia.com/Grimes-Motels.d602089-aaMotels.Travel-Guide-Accommodation) - [Farmstay in Grimes ](https://expedia.com/Grimes-Agritourism.d602089-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Grimes ](https://expedia.com/Grimes-Apart-Hotels.d602089-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Grimes ](https://expedia.com/Grimes-Bed-And-Breakfast.d602089-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there vacation rentals in Grimes? 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