Title: La Serena Vacation Rentals from $69: Search Short-Term Rentals | Expedia.com

[La Serena Travel Guide](https://expedia.com/La-Serena.dx2139)[Hotels in La Serena](https://expedia.com/La-Serena-Hotels.d2139.Travel-Guide-Hotels)[Flights to La Serena](https://expedia.com/Cheap-Flights-To-La-Serena.d2139.Travel-Guide-Flights)[Things to do in La Serena](https://expedia.com/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities)[Car Rentals in La Serena](https://expedia.com/Car-Rentals-In-La-Serena.d2139.Car-Rental-Guide)[La Serena Vacation Packages](https://expedia.com/La-Serena.d2139.Destination-Travel-Guides)

![Lighthouse at La Serena, Chile](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for La Serena vacation rentals

![3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/578aa723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/dac6a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/f5bcd040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Cabin (Cabaña para 1 a 2 personas) | Premium bedding, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/3757d586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña Villa Los Plátanos

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

$69 nightly

$69 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

![Business center](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/e8460db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Ocean View, Beachside | In-room dining](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/33710e4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Terrace/patio](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/83e753f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Living room | 49-inch flat-screen TV with cable channels, Smart TV](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/82544b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Choza VIP Turquesa en La Serena

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

Coquimbo

7.6/10

Good

(11 reviews)

"The apartment was very good for my needs and close to the conference centre. Safe, clean, well appointed. Yanitza was a big help and responsive to WhatsApp messages."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Andrew

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

![32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/3cd1e7d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Double or Twin Room | Living area | 32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/26ad5929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/682833ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hot tub, massages](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/9a5df107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Domos Dream hotel cabañas

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

La Serena

8.6/10

Excellent

(4 reviews)

"It was far away."

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Sergio

$81 nightly

$81 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/84c860a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 06 | Private kitchen | Fridge, oven, electric kettle, toaster](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/3a66e21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/8d5a7f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 04 | Living area | 32-inch TV with cable channels](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/ca42be32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ELDEPTO LA SERENA

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

Coquimbo

8.0/10

Very Good

(2 reviews)

"Boa localização de fácil acesso, tranquilidade e bom atendimento"

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Ricardo Horacio

$45 nightly

$45 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/19dd421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/093fb92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/3e664569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment | View from room](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/b486105f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel y Cabañas Vegasur

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

La Serena

8.6/10

Excellent

(94 reviews)

"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."

![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg)

Martin

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/6a3317ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | 2 bedrooms, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/acf8d706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/19578f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/5b10fbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Yunkai

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

Vicuña

$77 nightly

$77 total

Mar 21 - Mar 22

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/7815e33b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/84f4d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/ac9139f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/a4a4c864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elqui Valley Avocado Farm, 2-bedroom cabin in fabulous Vicuña with WiFi

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

Vicuña

$150 nightly

$150 total

Mar 19 - Mar 20

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

![Beach massages](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/d9d1bf94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking, City View | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/b39f32f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/5fe11d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Egyptian cotton sheets, premium bedding, memory foam beds](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/08998581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cosmopolita

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

"Highly recommend! The apartment was great and comfortable with everything you need and in a great location, and the owner Yanitza is incredibly nice and helpful and can tell you many things to do and see and is a very friendly person who makes you feel welcome."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

brett

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/9a70966a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/187df6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/29fc2b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/21510064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2nd Floor WiFi La Serena Beach & Casino!

[](https://www.expedia.com/Coquimbo-Hotels-2nd-Floor-WiFi-La-Serena-Beach-Casino.h37622526.Hotel-Information)

Coquimbo

10/10

Exceptional

(1 review)

"Excelente departamento, ubicación y comodidad, muchas gracias Yanitza por todo!!! Esperamos volver pronto!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniela

$143 nightly

$143 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-2nd-Floor-WiFi-La-Serena-Beach-Casino.h37622526.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/c428ca47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/28f96dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Oven](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/c1e397f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/09bfc77e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfortable apartment In coquimbo with parking space

[](https://www.expedia.com/Coquimbo-Hotels-Comfortable-Apartment-In-Coquimbo-With-Parking-Space.h116472356.Hotel-Information)

Coquimbo

$72 nightly

$72 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-Comfortable-Apartment-In-Coquimbo-With-Parking-Space.h116472356.Hotel-Information)

![1 bedroom](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/bc839c97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/cda1ea8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/d0f2ada3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/06afea6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Loft, the Horseshoe 02 passengers

[](https://www.expedia.com/Coquimbo-Hotels-Loft.h36344347.Hotel-Information)

coquimbo

$59 nightly

$59 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-Loft.h36344347.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/630b114c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/56c8df19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Onsite parking](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/5655ceb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/cf6506a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Enjoy Coquimbo Apartment one block away

[](https://www.expedia.com/Coquimbo-Hotels-Enjoy-Coquimbo-Apartment-One-Block-Away.h77064270.Hotel-Information)

coquimbo

$159 nightly

$183 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-Enjoy-Coquimbo-Apartment-One-Block-Away.h77064270.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/11ff680b_edited_b162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/de5d34bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/w1308h993x0y1-e623b8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/w1308h994x0y0-ab517709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elegant apartment in a privileged location in the heart of Avenida del Mar.

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h120897204.Hotel-Information)

La Serena

8.0/10

Very Good

(1 review)

"The building is nice because it is conveniently located near the beach and lots of shops and restaurants. It was easy to locate the tower and room we rented. The rooms were clean, but the apartment and all bedding smelled of smoke. I am not a smoker so this was unexpected and disappointing. Also, the noise level is quit high because the walls are very thin."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elena

$152 nightly

$152 total

Mar 21 - Mar 22

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h120897204.Hotel-Information)

![Classic Apartment, Ocean View | Living area](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/a3662af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Private kitchen](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/1b824154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Living area](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/ee719a38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Private kitchen](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/d14df2f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Depto Serena Golf

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

La Serena

$297 nightly

$297 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/de2bdd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/4f881c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/1437bf75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/5f596ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "Nicoland" Playa, piscina, La Serena

[](https://www.expedia.com/La-Serena-Hotels-Nicoland-Playa.h79128717.Hotel-Information)

La Serena

10/10

Exceptional

(1 review)

"Hermoso departamento,muy bien amoblado, no le falta nada. Excelente ubicación. Queremos destacar la atención de la anfitriona Yanitza, quien siempre estuvo atenta a todas nuestras necesidades y consultas. De seguro volveremos!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniela

$140 nightly

$140 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Nicoland-Playa.h79128717.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/8ed7542e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/e4cc8ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/5c670165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/5d253778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Self-sustainable Cabin with beautiful views of the Elqui Valley,Pet Friend

[](https://www.expedia.com/La-Serena-Hotels-Cozy-Self-Sustainable-Cabin-With-Beautiful-Views-Of-The-Elqui-Valley.h102222748.Hotel-Information)

La Serena

$83 nightly

$83 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Cozy-Self-Sustainable-Cabin-With-Beautiful-Views-Of-The-Elqui-Valley.h102222748.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/9327bcce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/2d21f2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/b9d651f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/6338524d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful & unique beach apartament in the oldest bay and coastal city of Chile 

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

La Serena

$110 nightly

$110 total

Mar 19 - Mar 20

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/115000000/114150000/114144900/114144802/9be0d7a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114150000/114144900/114144802/5e52d9d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/115000000/114150000/114144900/114144802/d9b89373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/115000000/114150000/114144900/114144802/a6af2056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### FAMILY APARTMENT, 5 MIN. FROM THE BEACH AND ROUTE 5, OCEAN VIEW.

[](https://www.expedia.com/Coquimbo-Hotels-FAMILY-APARTMENT.h114144802.Hotel-Information)

Coquimbo

$21,882 nightly

$21,882 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-FAMILY-APARTMENT.h114144802.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/85a38ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/868e092f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/bcb262bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/14ea8a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hermoso Departamento, Ideal Para Escapadas, a 15 Minutos de la Playa

[](https://www.expedia.com/Coquimbo-Hotels-Hermoso-Departamento.h101430739.Hotel-Information)

Coquimbo

$70 nightly

$70 total

Mar 19 - Mar 20

[](https://www.expedia.com/Coquimbo-Hotels-Hermoso-Departamento.h101430739.Hotel-Information)

![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/d54d61b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/e0661065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/d474b0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/99a0d71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serene and Luxury Refuge in the Elqui Valley: Valle Hermoso House

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h99427287.Hotel-Information)

Coquimbo

$366 nightly

$366 total

Mar 20 - Mar 21

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h99427287.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-01&endDate=2026-04-02&regionId=2139&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=APARTMENT)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=VACATION_HOME)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=APART_HOTEL)

Condos

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CONDO)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=COTTAGE)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CABIN)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CHALET)

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## Top La Serena Hotel Reviews

![Primera Hacienda Hotel Boutique](https://images.trvl-media.com/lodging/14000000/13360000/13357200/13357169/46bfad8b_y.jpg)

### Primera Hacienda Hotel Boutique

10/10 Excellent

"The property was beautiful, the breakfast was delicious. We had a great time!"

[](https://expedia.com/La-Serena-Hotels-Primera-Hacienda-Hotel-Boutique.h13357169.Hotel-Information)

![Hostal La Serena](https://images.trvl-media.com/lodging/42000000/41510000/41509600/41509532/ba4c6d63_y.jpg)

### Hostal La Serena

10/10 Excellent

"El desayuno es muy completo y rico, muy amable el trato de Katy y de don Marcelo. "

[](https://expedia.com/La-Serena-Hotels-Hostal-La-Serena.h41509532.Hotel-Information)

![Hotel Club La Serena](https://images.trvl-media.com/lodging/1000000/430000/428300/428299/55b3bab7_y.jpg)

### Hotel Club La Serena

10/10 Excellent

"Excellent location!"

[](https://expedia.com/La-Serena-Hotels-Hotel-Club-La-Serena.h428299.Hotel-Information)

![Hotel Costa Real](https://images.trvl-media.com/lodging/28000000/27180000/27173400/27173320/88de3f01_y.jpg)

### Hotel Costa Real

10/10 Excellent

"Clean and the staff was excellent Will definitely come back "

[](https://expedia.com/La-Serena-Hotels-Hotel-Costa-Real.h27173320.Hotel-Information)

![Hotel Canto del Mar](https://images.trvl-media.com/lodging/113000000/112970000/112966800/112966711/047ed19f_y.jpg)

### Hotel Canto del Mar

4/10 Poor

"no wheelchair access, no elevator. no a/c "

[](https://expedia.com/La-Serena-Hotels-Hotel-Canto-Del-Mar.h112966711.Hotel-Information)

![Aji Verde Hostel](https://images.trvl-media.com/lodging/22000000/22000000/21992300/21992256/5813347a_y.jpg)

### Aji Verde Hostel

4/10 Poor

"The hostel is located near the market, which makes the area feel unsafe at night. The staff and volunteers were inattentive. The rooms are very dark and overcrowded with too many beds, leaving little space to move around or store luggage. There is only a small window, which doesn’t provide enough natural light or ventilation. Although there are a few seating areas, they feel cramped and are furnished with unattractive furniture. I do not recommend this hostel."

[](https://expedia.com/La-Serena-Hotels-Aji-Verde-Hostel.h21992256.Hotel-Information)

![Hotel Chagual](https://images.trvl-media.com/lodging/25000000/24220000/24214200/24214154/f5815869_y.jpg)

### Hotel Chagual

4/10 Poor

"More a Hostel, that an boutique hotel "

[](https://expedia.com/La-Serena-Hotels-Hotel-Chagual.h24214154.Hotel-Information)

![Hotel Diego de Almagro La Serena](https://images.trvl-media.com/lodging/16000000/15580000/15570400/15570373/332a6c16_y.jpg)

### Hotel Diego de Almagro La Serena

10/10 Excellent

"Efficient front-desk staff, a comfortable quiet room on the 3rd floor,and an excellent breakfast "

[](https://expedia.com/La-Serena-Hotels-Hotel-Diego-De-Almagro-La-Serena.h15570373.Hotel-Information)

![Hotel Diego de Almagro La Serena Express](https://images.trvl-media.com/lodging/111000000/110440000/110439900/110439848/5ac899a7_y.jpg)

### Hotel Diego de Almagro La Serena Express

8/10 Good

"Room quality was very good and the room was very clean every day,"

[](https://expedia.com/La-Serena-Hotels-Hotel-Diego-De-Almagro-La-Serena-Express.h110439848.Hotel-Information)

## Find out more about La Serena

**Everything you need to know about La Serena vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Serena vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Serena vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**La Serena vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in La Serena. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Serena in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on La Serena rentals**

At Expedia, we put the best La Serena vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Serena rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Serena vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Serena. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in La Serena

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- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
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- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Apartments in La Serena ](https://expedia.com/La-Serena-Apartments.d2139-aaApartments.Travel-Guide-Accommodation)
- [Cottages in La Serena ](https://expedia.com/La-Serena-Cottages.d2139-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in La Serena ](https://expedia.com/La-Serena-Cabins.d2139-aaCabins.Travel-Guide-Accommodation)
- [Hostels in La Serena ](https://expedia.com/La-Serena-Hostels.d2139-aaHostels.Travel-Guide-Accommodation)
- [Aparthotels in La Serena ](https://expedia.com/La-Serena-Apart-Hotels.d2139-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in La Serena ](https://expedia.com/La-Serena-Bed-And-Breakfast.d2139-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Villas in La Serena ](https://expedia.com/La-Serena-Villas.d2139-aaVillas.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in La Serena?

### What are some of the best vacation rentals in La Serena?

### How many vacation rentals will I find in La Serena?

### What can I see and do in La Serena?

### What are vacation rentals like in La Serena?

### Expedia's Latest Trends

Hotels

- [Hotel Rooms in Paiguano](https://expedia.com/Paiguano-Hotels.d6344315.Travel-Guide-Hotels)
- [Hotel Rooms in San Pedro de Atacama](https://expedia.com/San-Pedro-De-Atacama-Hotels.d500224.Travel-Guide-Hotels)
- [Hotel Rooms in La Higuera](https://expedia.com/La-Higuera-Hotels.d6203805.Travel-Guide-Hotels)
- [Hotel Rooms in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)
- [Hotel Rooms in Vina del Mar](https://expedia.com/Vina-Del-Mar-Hotels.d6053651.Travel-Guide-Hotels)
- [Hotel Rooms in Andacollo](https://expedia.com/Andacollo-Hotels.d6203778.Travel-Guide-Hotels)

Flights

- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Torres-Del-Paine.d6127101.Travel-Guide-Flights)
- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Punta-Arenas.d2904.Travel-Guide-Flights)
- [Flights to CJC](https://expedia.com/Cheap-Flights-To-San-Pedro-De-Atacama.d500224.Travel-Guide-Flights)
- [Flights to ANF](https://expedia.com/Cheap-Flights-To-Antofagasta.d382.Travel-Guide-Flights)
- [Flights to CCP](https://expedia.com/Cheap-Flights-To-Los-Angeles.d500226.Travel-Guide-Flights)
- [Flights to VAP](https://expedia.com/Cheap-Flights-To-Cartagena.d6236111.Travel-Guide-Flights)

Cars

- [Car rentals in San Pedro de Atacama](https://expedia.com/Car-Rentals-In-San-Pedro-De-Atacama.d500224.Car-Rental-Guide)
- [Car rentals in Los Angeles](https://expedia.com/Car-Rentals-In-Los-Angeles.d500226.Car-Rental-Guide)
- [Car rentals in Punta Arenas](https://expedia.com/Car-Rentals-In-Punta-Arenas.d2904.Car-Rental-Guide)
- [Get Your Car Car Rentals In Vicuna](https://expedia.com/Get-Your-Car-Car-Rentals-In-Vicuna.d6203808-c1120.Car-Rental-Guide-Suppliers)
- [Car rental La Serena Airport (LSC)](https://expedia.com/Car-Rentals-In-La-Florida.d6029785.Car-Rental-Guide)

Activities

- [Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d6336623.Travel-Guide-Activities)
- [Things to do in Valparaiso](https://expedia.com/Things-To-Do-In-Valparaiso.d602827.Travel-Guide-Activities)
- [Things to do in Coquimbo](https://expedia.com/Things-To-Do-In-Coquimbo.d6024027.Travel-Guide-Activities)
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Packages

- [Museo Arqueológico](https://expedia.com/Museo-Arqueologico-La-Serena.d553248621532374497.Vacation-Attraction)
- [Mall Plaza La Serena](https://expedia.com/Mall-Plaza-La-Serena-La-Serena.d6311978.Vacation-Attraction)
- [Observatorio Turístico Collowara](https://expedia.com/Observatorio-Turistico-Collowara-La-Serena.d553248621532374491.Vacation-Attraction)

General

- [Visit Concepción](https://expedia.com/Concepcion.dx790)
- [Visit Valparaiso](https://expedia.com/Valparaiso.dx602827)
- [Visit Vina del Mar](https://expedia.com/Vina-Del-Mar.dx6053651)
- [Visit Los Andes](https://expedia.com/Los-Andes.dx6272982)
- [Visit Hanga Roa](https://expedia.com/Hanga-Roa.dx6053647)