This seagoing vessel is often on the itineraries of travelers to St. Charles Historic District. But Lewis & Clark Boathouse and Nature Center isn't the only drawcard here. Ameristar Casino St. Charles, Hollywood Casino Amphitheatre, and Historic Main Street are some other recommended attractions nearby.
Lewis & Clark Boathouse and Nature Center Tours
Visit Lewis & Clark Boathouse and Nature Center
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Price found within the past 48 hours. Click for updated prices.
Comfort Inn Sullivan
Price was $769, price is now $638 per person
$638
per person
Dec 30 - Jan 5
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to St. Louis (STL)
8.6/10 Excellent! (785 reviews)
Room was nice. Hotel is renovating at the moment. Beds were a little high.
Reviewed on Nov 10, 2025
The West End
Central West End
Price was $559, price is now $469 per person
$469
per person
Dec 18 - Dec 21
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
8.4/10 Very Good! (349 reviews)
Price is high compare to size of room we got and no breakfast option only coffee. I think in this price can get better option.
Reviewed on Nov 8, 2025
Popular places to visit
Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.
Historic Main Street
You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this walkable area.
Ameristar Casino St. Charles
Why not try your luck with a visit to Ameristar Casino St. Charles during your time in St. Charles? Experience the great live music and acclaimed theater scene in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this walkable area.
First Missouri State Capitol Historic Site
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.
SSM Health St. Joseph Hospital
Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.
Best Lodging Options Near Lewis & Clark Boathouse and Nature Center
Check availability on hotels close to Lewis & Clark Boathouse and Nature Center
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1310 Bass Pro Drive, St. Charles, MO
Comfort Suites St Charles - St Louis
1400 S 5th St, St. Charles, MO
Best Western Plus The Charles Hotel
1425 South 5th Street, St. Charles, MO
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Hampton Inn & Suites St. Charles Old Town Area
1410 SOUTH 5TH STREET, St. Charles, MO
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive, St. Charles, MO
Historic headquarters of city founder! Gated parking!
Saint Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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