An ancient stone corridor with arches, potted plants, and a dome structure in the background.

Mission Vacation Rentals

Check prices for these dates

In two weeks
Oct 23 - Oct 25
In two months
Dec 4 - Dec 6
In three months
Jan 1 - Jan 3
In four months
Jan 29 - Jan 31

Our top choices for Mission vacation rentals

A modern kitchen with a central island, stainless steel appliances, and wooden cabinetry.

1. The Cozy Red Barn

The Cozy Red Barn
Mission
10.0 out of 10, Exceptional, (2 reviews)
"The property was very, very clean, pleasant and more than met our expectations. We will definitely book again!"
United States
Selma P.
$174 nightly
The price is $194
Oct 13 - Oct 14
Total with taxes and fees
The Cozy Red Barn
A modern bedroom with a large bed, a patterned wall, and a mounted TV.

2. Red luxe home -king suite, jacuzzi. outdoor lounge

Red luxe home -king suite, jacuzzi. outdoor lounge
Mission
10.0 out of 10, Exceptional, (2 reviews)
"Overall great experience, spacious home and amazing backyard"
United States
Emmanuel M.
$186 nightly
The price is $195
Oct 11 - Oct 12
Total with taxes and fees
Red luxe home -king suite, jacuzzi. outdoor lounge
A bedroom with a bed, nightstands, a ceiling fan, a window with blinds, and a door leading to a bathroom.

3. Charming 2-bedroom house in nice gated community with AC , shared swiming pool

Charming 2-bedroom house in nice gated community with AC , shared swiming pool
Mission
9.4 out of 10, Exceptional, (6 reviews)
$95 nightly
The price is $100
Oct 19 - Oct 20
Total with taxes and fees
Charming 2-bedroom house in nice gated community with AC , shared swiming pool
A modern kitchen with green cabinets, a black and white patterned floor, and a large island.

4. New Listing ! Modern Lakefront Retreat

New Listing ! Modern Lakefront Retreat
Mission
10.0 out of 10, Exceptional, (5 reviews)
"Very luxurious place in the heart of Mission. Plenty of places to see and eat right around the corner. Awesome wildlife right in the backyard as the property is next to the water. Host was awesome with any questions as they replied within five minutes every time."
United States
Christopher B.
$315 nightly
The price is $332
Oct 11 - Oct 12
Total with taxes and fees
New Listing ! Modern Lakefront Retreat
A large, modern house with a spacious driveway and well-maintained landscaping.

5. Grand estate in upscale neighborhood w/ nice pool

Grand estate in upscale neighborhood w/ nice pool
Mission
9.4 out of 10, Exceptional, (34 reviews)
"This was a great place, beautiful kitchen. Our family really enjoyed the back patio. "
United States
Laura A.
$452 nightly
The price is $452
Oct 18 - Oct 19
Total with taxes and fees
Grand estate in upscale neighborhood w/ nice pool
A swimming pool with a sunset view, a covered patio with lounge chairs, and a wooden fence.

6. Cozy stay in Mission - With Pool & Patio

Cozy stay in Mission - With Pool & Patio
Mission
9.0 out of 10, Wonderful, (4 reviews)
"very cozy "
United States
Alessandra G.
$336 nightly
The price is $354
Oct 12 - Oct 13
Total with taxes and fees
Cozy stay in Mission - With Pool & Patio
An outdoor seating area with a view of a lake and trees.

7. Lake Home: Relax and Unwind in Mission Hidden Gem

Lake Home: Relax and Unwind in Mission Hidden Gem
Mission
9.4 out of 10, Exceptional, (13 reviews)
$577 nightly
The price is $608
Oct 12 - Oct 13
Total with taxes and fees
Lake Home: Relax and Unwind in Mission Hidden Gem
A living room with a fireplace, a television mounted on the wall, and a patterned armchair.

8. Grandmas Old Place

Grandmas Old Place
Mission
$219 nightly
The price is $231
Oct 11 - Oct 12
Total with taxes and fees
Grandmas Old Place
A kitchen with wooden cabinets, a built-in oven, and a microwave.

9. 2 Full Beds | Non-Smoking, Micfridge

2 Full Beds | Non-Smoking, Micfridge
Mission
$70 nightly
The price is $79
Nov 1 - Nov 2
Total with taxes and fees
2 Full Beds | Non-Smoking, Micfridge
A wooden deck with a sofa and railing overlooking a lake at sunset.

10. Lakefront Oasis Casa Hoyo 12 Private Retreat

Lakefront Oasis Casa Hoyo 12 Private Retreat
Mission
10.0 out of 10, Exceptional, (1 review)
"Beautiful home great host"
United States
Lily C.
$581 nightly
The price is $612
Oct 18 - Oct 19
Total with taxes and fees
Lakefront Oasis Casa Hoyo 12 Private Retreat
A single-story house with a covered porch and a small front yard.

11. Charming 2bedroom house in Mission , a few minutes to Shary Rd and La Plaza Mall

Charming 2bedroom house in Mission , a few minutes to Shary Rd and La Plaza Mall
Mission
$96 nightly
The price is $100
Oct 14 - Oct 15
Total with taxes and fees
Charming 2bedroom house in Mission , a few minutes to Shary Rd and La Plaza Mall
A modern kitchen with white cabinets, a stainless steel refrigerator, a built-in oven, and a granite countertop.

12. 3 Bd/2 Ba open concept home with plenty of parking

3 Bd/2 Ba open concept home with plenty of parking
Mission
9.8 out of 10, Exceptional, (10 reviews)
"Everything was really good "
United States
America R.
$190 nightly
The price is $200
Oct 14 - Oct 15
Total with taxes and fees
3 Bd/2 Ba open concept home with plenty of parking
A modern kitchen with a central island, white cabinetry, and a dining area with a wooden table and chairs.

13. Modern Cozy Home Near Everything.

Modern Cozy Home Near Everything.
Alton
10.0 out of 10, Exceptional, (2 reviews)
"An amazing location. Host was available to answer any questions we had. Very spacious. Would love to stay again next time we are in town."
United States
jessica d.
$233 nightly
The price is $245
Oct 11 - Oct 12
Total with taxes and fees
Modern Cozy Home Near Everything.
A hotel room with a bed, a desk, and a chair.

14. 1 Queen Bed | Non-Smoking, Micfridge

1 Queen Bed | Non-Smoking, Micfridge
Mission
$65 nightly
The price is $74
Nov 1 - Nov 2
Total with taxes and fees
1 Queen Bed | Non-Smoking, Micfridge
A rectangular swimming pool with a no diving sign at the bottom, surrounded by a brick border.

15. 1 Queen Bed | Non-Smoking

1 Queen Bed | Non-Smoking
Mission
$61 nightly
The price is $68
Nov 1 - Nov 2
Total with taxes and fees
1 Queen Bed | Non-Smoking
A laundry room with a washing machine, dryer, and a window with blinds.

16. 1 Queen Bed | Mobility Accessible Tub Nsmk

1 Queen Bed | Mobility Accessible Tub Nsmk
Mission
$61 nightly
The price is $68
Nov 1 - Nov 2
Total with taxes and fees
1 Queen Bed | Mobility Accessible Tub Nsmk
A hotel room with a bed, a desk, a chair, a television, and a mirror.

17. 2 Full Beds | Non-Smoking

2 Full Beds | Non-Smoking
Mission
$61 nightly
The price is $68
Nov 1 - Nov 2
Total with taxes and fees
2 Full Beds | Non-Smoking
A modern living room with a ceiling fan, a TV, and a dining area with a kitchen in the background.

18. Modern Luxe Retreat - King Suite - Self Check-In

Modern Luxe Retreat - King Suite - Self Check-In
Alton
$169 nightly
The price is $178
Oct 10 - Oct 11
Total with taxes and fees
Modern Luxe Retreat - King Suite - Self Check-In
A two-story house with a brick facade, a large arched entrance, and a number '14600' sign.

19. Cozy 1-bedroom Casita in fantastic Tres Lagos with AC

Cozy 1-bedroom Casita in fantastic Tres Lagos with AC
McAllen
$81 nightly
The price is $85
Oct 11 - Oct 12
Total with taxes and fees
Cozy 1-bedroom Casita in fantastic Tres Lagos with AC
A modern kitchen with dark wood cabinets, stainless steel appliances, and a granite countertop.

20. Stylish Condo w/ Pool, Near Everything

Stylish Condo w/ Pool, Near Everything
McAllen
10.0 out of 10, Exceptional, (22 reviews)
"Nice and clean,"
United States
Carlos
$223 nightly
The price is $253
Oct 12 - Oct 13
Total with taxes and fees
Stylish Condo w/ Pool, Near Everything
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Hotel Reviews

SureStay Hotel By Best Western Mission

SureStay Hotel By Best Western Mission

10/10 Excellent
"Todo ok"
Gerardo 1-night trip
Posted 18 hours ago
SureStay Hotel By Best Western Mission

Find out more about Mission

Everything you need to know about Mission vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mission vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mission vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mission vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mission. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mission in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $100 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mission rentals

At Expedia, we put the best Mission vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mission rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mission vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mission. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Mission?

Yes, we give you a choice of vacation rentals near popular sights in Mission, or you can select a more remote option if you're looking for a relaxing stay. The shops and restaurants are several reasons why visitors like Mission. Make sure you have time to check out the entertainment choices and university setting during your trip.

What's the top vacation rental that Mission has to offer?

Grand estate in upscale neighborhood w/ nice pool: This highly rated vacation home rental in Mission offers a balcony, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a hot tub. Some other top choices in Mission are Cozy Home on RGV and Charming 2-bedroom house in nice gated community with AC , shared swiming pool.

How many vacation rentals are there in Mission?

Expedia has 57 vacation rentals for your stay in Mission.

What can I see and do in Mission?

Rio Grande and Anzalduas Park are a couple of lovely local spots to get outside and enjoy nature. Shary Municipal Golf Course and Bentsen-Rio Grande Valley State Park are other places to visit while you're in town.

What’s a vacation rental in Mission like?

Vacation rentals are private properties you can stay in for a few weeks or just a few days in Mission. Vacation rentals provide amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a sanitized environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.