--- title: "Top 10 Hotels in Mosopuquio (from $23) 2026 - Competitive Prices | Expedia" description: "Find 226 of the best hotels in Mosopuquio in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable." canonical: "https://www.expedia.com/Mosopuquio-Hotels.d553248635975855328.Travel-Guide-Hotels" language: en-US market: US currency: USD prices_as_of: 2026-11-13T09:42:29Z --- Plan your trip - [Mosopuquio Travel Guide](https://www.expedia.com/Mosopuquio.dx553248635975855328) - [Flights to Mosopuquio](https://www.expedia.com/Cheap-Flights-To-Mosopuquio.d553248635975855328.Travel-Guide-Flights) - [Car Rentals in Mosopuquio](https://www.expedia.com/Car-Rentals-In-Mosopuquio.d553248635975855328.Car-Rental-Guide) - [Mosopuquio Vacation Packages](https://www.expedia.com/Mosopuquio.d553248635975855328.Destination-Travel-Guides) - [Vacation Rentals in Mosopuquio](https://www.expedia.com/Mosopuquio-Vacation-Rentals.d553248635975855328.Travel-Guide-VacationRentals) # Find hotels in Mosopuquio from $23 ### Upfront pricing Our total price for your stay includes taxes and fees ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mosopuquio [Pet friendly](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=PETS) [Hot tub](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=HOT%5FTUB) [Pool](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=POOL) [Spa](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=SPA%5FON%5FSITE) [Apart­ment](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=APARTMENT) [Family friendly](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&travelerType=family%5Ffriendly) [Apart hotel](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=APART%5FHOTEL) [Waterpark](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&amenities=WATER%5FPARK) [Condo](https://www.expedia.com/Hotel-Search?destination=Mosopuquio,%20Characato,%20Arequipa%20Region,%20Peru®ionId=553248635975855328&latLong=-16.44919,-71.354903&adults=2&startDate=2026-11-20&d1=2026-11-20&endDate=2026-11-22&d2=2026-11-22&lodging=CONDO) ## Check prices for these dates [Check prices for these dates, December 13 – 14, 2026](https://www.expedia.com/Hotel-Search?regionId=553248635975855328&startDate=2026-12-13&endDate=2026-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) [View in a map](https://www.expedia.com/Hotel-Search?regionId=553248635975855328&stayLength=1&daysInFuture=30&pwaOverlay=map) ## Our top choices for Mosopuquio hotels ### [1\. Hotel El Lago by Luoxo](https://www.expedia.com/Arequipa-Hotels-BTH-Hotel-Arequipa-Lake.h1631543.Hotel-Information) ![A lakeside building with a reflection in the water, surrounded by trees.](https://images.trvl-media.com/lodging/2000000/1640000/1631600/1631543/03a47170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Sabandía - Guest rating: 8.4/10 (Very good, 191 reviews) - Price: $71 nightly, $71 total, Nov 14 - Nov 15 - Review: Beautiful property with a very helpful staff. The manager was very accomodating and friendly. Great food at the restaurant too., by Cory ### [2\. DM Hoteles Arequipa](https://www.expedia.com/Arequipa-Hotels-DM-Hoteles-Arequipa.h12319428.Hotel-Information) ![A hotel room with a large bed, wooden headboard, a bedside table with a lamp, a nightstand with a phone, and a window with curtains.](https://images.trvl-media.com/lodging/13000000/12320000/12319500/12319428/15016037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cerro Colorado District - Guest rating: 7.2/10 (Good, 5 reviews) - Price: $76 nightly, $76 total, Dec 12 - Dec 13 - Review: Para ser un Hotel de una cadena importante fue muy decepcionante que alguno de su personal no sea servicial y perdida en dar información de los servicios esto me toco vivir con la recepcionista. Los precios que se pagan no están de acuerdo a la calidad de servicio. , by lino ### [3\. Sonesta Hotel Arequipa](https://www.expedia.com/Arequipa-Hotels-Sonesta-Hotel-Arequipa.h34550097.Hotel-Information) ![A modern building with a prominent glass facade and a unique triangular design.](https://images.trvl-media.com/lodging/35000000/34560000/34550100/34550097/2baefba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cerro Colorado District - Guest rating: 9.6/10 (Exceptional, 226 reviews) - Price: $116 nightly, $116 total, Nov 20 - Nov 21 - Review: Great location. Great breakfast bar and superb attention to detail. Customer service was good, very pleasant people. Will stay again upon my return to Arequipa., by denisse ### [4\. Hostal Lirium](https://www.expedia.com/Arequipa-Hotels-Hostal-Lirium.h78298613.Hotel-Information) ![A hotel room with a wooden headboard, a bed with white and blue bedding, a bedside table with a lamp, a chair, and a large window with curtains.](https://images.trvl-media.com/lodging/79000000/78300000/78298700/78298613/baa8edf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Sachaca - Guest rating: 10/10 (Exceptional, 2 reviews) - Price: $24 nightly, $24 total, Nov 22 - Nov 23 - Review: The room was pleasant and always clean for us after a long day. Breakfast was always on the table before we showed up to the table. Staff was very friendly and helpful. A 10 min walk away from the Plaza de Armas, quite place if you like to stay away from the noise. , by Alexander ### [5\. HOTEL ALTIVA](https://www.expedia.com/Arequipa-Hotels-HOTEL-ALTIVA.h121270456.Hotel-Information) ![A hotel lobby with a reception desk, a seating area with patterned chairs, a glass coffee table, and a chandelier.](https://images.trvl-media.com/lodging/122000000/121280000/121270500/121270456/6d14cfde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cayma - Price: $28 nightly, $28 total, Nov 18 - Nov 19 ### [6\. Hotel TerraMistica Monasterio](https://www.expedia.com/Arequipa-Hotels-Hotel-TerraMistica-Monasterio.h106419312.Hotel-Information) ![A hotel room with a large bed, a chair, a nightstand, a small table, and a window with curtains.](https://images.trvl-media.com/lodging/107000000/106420000/106419400/106419312/ecf5c426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: José Luis Bustamante y Rivero - Guest rating: 10/10 (Exceptional, 2 reviews) - Price: $45 nightly, $45 total, Nov 15 - Nov 16 - Review: Very nice location and friendly staff ； room is not big, but adequate; will stay again if I am back to Arequipa, by Sheauing ### [7\. Los Tambos - Boutique](https://www.expedia.com/Arequipa-Hotels-Los-Tambos.h3019439.Hotel-Information) ![A hotel room with a bed, bedside table, lamp, and a small table with a vase of sunflowers.](https://images.trvl-media.com/lodging/4000000/3020000/3019500/3019439/aeb0ea74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.6/10 (Exceptional, 562 reviews) - Price: $60 nightly, $60 total, Dec 2 - Dec 3 - Review: Loved this hotel ! The staff is super accommodating and helpful, the breakfast was really good and the view from the terrace was wonderful!, by sabine ### [8\. Qori Arequipa](https://www.expedia.com/Arequipa-Hotels-Qori-Arequipa.h133725457.Hotel-Information) ![A hotel room with a bed, a desk, a chair, a window with curtains, and a view of the outside.](https://images.trvl-media.com/lodging/134000000/133730000/133725500/133725457/81c533b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cerro Colorado District - Price: $45 nightly, $45 total, Nov 14 - Nov 15 ### [9\. Xima Arequipa Crismar](https://www.expedia.com/Arequipa-Hotels-Crismar-Experience-By-Xima-Hotels.h1525054.Hotel-Information) ![A hotel room with a large window offering a view of a cityscape and a prominent building at dusk.](https://images.trvl-media.com/lodging/2000000/1530000/1525100/1525054/9ed415be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 8.6/10 (Excellent, 23 reviews) - Price: $55 nightly, $55 total, Dec 12 - Dec 13 - Review: Great wonderful clean hotel with attentive staff. Best stay in Arequipa so far. Spacious renovated rooms and delicious breakfast. This is the hotel I will always be staying when visiting the city., by Lana ### [10\. HOTEL INKALMA SANTA MARTA](https://www.expedia.com/Arequipa-Hotels-INKALMA-CENTRO.h117059106.Hotel-Information) ![A modern living room with a flat-screen TV mounted on a wooden wall, a wooden bench, and a small table.](https://images.trvl-media.com/lodging/118000000/117060000/117059200/117059106/ddbeba91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9/10 (Wonderful, 17 reviews) - Price: $34 nightly, $34 total, Dec 2 - Dec 3 - Review: Nice place, location, by John ### [11\. Palla Boutique Hotel](https://www.expedia.com/Arequipa-Hotels-Palla-Boutique-Hotel.h14852197.Hotel-Information) ![A rooftop terrace with outdoor seating, a large umbrella, and a view of the cityscape.](https://images.trvl-media.com/lodging/15000000/14860000/14852200/14852197/115333ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.6/10 (Exceptional, 132 reviews) - Price: $78 nightly, $78 total, Dec 13 - Dec 14 - Review: Staff were very helpful and everything was perfect, by Raymond ### [12\. Hotel Piru Wasi Arequipa](https://www.expedia.com/Arequipa-Hotels-Hotel-Piru-Wasi-Arequipa.h23393398.Hotel-Information) ![A reception area with a counter, a painting, and a seating area with a chair and a table.](https://images.trvl-media.com/lodging/24000000/23400000/23393400/23393398/4ffade47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Yanahuara - Guest rating: 9.4/10 (Exceptional, 3 reviews) - Price: $31 nightly, $31 total, Nov 14 - Nov 15 - Review: Maribele was great, she let us check in early, and held our bags until the afternoon the day we were leaving. She was very helpful. Breakfast was great as well as the price. Close to the plasa del armas and not to far from the mall. She also spoke alot of English which really helps. , by Vanessa ### [13\. Hotel La Cuesta de Cayma](https://www.expedia.com/Arequipa-Hotels-Hotel-La-Cuesta-De-Cayma.h6233901.Hotel-Information) ![A bathtub with rose petals and champagne glasses.](https://images.trvl-media.com/lodging/7000000/6240000/6234000/6233901/518d1229.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cayma - Guest rating: 8.6/10 (Excellent, 34 reviews) - Price: $70 nightly, $70 total, Dec 1 - Dec 2 - Review: Good hotel. Staff were very helpful, by Max ### [14\. Santa Marta Hotel Arequipa](https://www.expedia.com/Arequipa-Hotels-Santa-Marta-Boutique-Hotel.h14632207.Hotel-Information) ![A courtyard with stone flooring, potted plants, and outdoor seating.](https://images.trvl-media.com/lodging/15000000/14640000/14632300/14632207/be5a214e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.6/10 (Exceptional, 25 reviews) - Price: $65 nightly, $65 total, Nov 14 - Nov 15 - Review: good location and friendly staff, by Sebastien ### [15\. Casa Arequipa](https://www.expedia.com/Arequipa-Hotels-Casa-Arequipa.h1785043.Hotel-Information) ![A breakfast table with a variety of dishes, a vase with flowers, and a potted plant by a window with columns.](https://images.trvl-media.com/lodging/2000000/1790000/1785100/1785043/e8b9a5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.4/10 (Exceptional, 80 reviews) - Price: $62 nightly, $62 total, Nov 14 - Nov 15 - Review: Very helpful staff., by John ### [16\. Hotel Santa Rosa](https://www.expedia.com/Arequipa-Hotels-Hotel-Santa-Rosa.h33638565.Hotel-Information) ![A bathroom with a shower, toilet, and a trash bin.](https://images.trvl-media.com/lodging/34000000/33640000/33638600/33638565/13251f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.2/10 (Wonderful, 27 reviews) - Price: $49 nightly, $49 total, Nov 16 - Nov 17 - Review: Love it! Cute hotel right in the middle of the historic center and one of the busiest streets, plenty of restaurants and bars to walk to right on the same street. Would definitely stay here again!, by Christian ### [17\. Palacio Guaqui](https://www.expedia.com/Arequipa-Hotels-Palacio-Guaqui.h103911987.Hotel-Information) ![A bedroom with a large bed, a wooden nightstand, a vintage-style sink, and a clawfoot bathtub.](https://images.trvl-media.com/lodging/104000000/103920000/103912000/103911987/bd99ca42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.8/10 (Exceptional, 17 reviews) - Price: $279 nightly, $279 total, Dec 1 - Dec 2 - Review: Amazing hotel with incredible staff , by Yasmine ### [18\. Maison du Soleil](https://www.expedia.com/Arequipa-Hotels-Maison-Du-Soleil.h100892101.Hotel-Information) ![A multi-level interior with a staircase, potted plants, and a statue.](https://images.trvl-media.com/lodging/101000000/100900000/100892200/100892101/a771515d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 8.8/10 (Excellent, 29 reviews) - Price: $38 nightly, $38 total, Nov 19 - Nov 20 - Review: There was a misunderstanding on booking on my part as I was not sure what days I would stay in Arequipa, The staff bent over backwards to a accommodate me and help me out. The place is really nice and close to points of interest., by Angel D ### [19\. Katari Hotel At Plaza de Armas](https://www.expedia.com/Arequipa-Hotels-Katari-Hotel-At-Plaza-De-Armas.h11828834.Hotel-Information) ![An outdoor dining area with tables and chairs, lanterns, and a view of a historic building with two towers and a mountain in the background.](https://images.trvl-media.com/lodging/12000000/11830000/11828900/11828834/2281f362.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 9.4/10 (Exceptional, 328 reviews) - Price: $104 nightly, $104 total, Dec 14 - Dec 15 - Review: The beds were very large and comfortable. Breakfast was excellent as well as the location., by James ### [20\. Vita Hoteles Arequipa](https://www.expedia.com/Arequipa-Hotels-Vita-Hoteles-Arequipa.h49257602.Hotel-Information) ![A rooftop terrace with a glass balustrade, outdoor seating, and a view of the sunset over a cityscape.](https://images.trvl-media.com/lodging/50000000/49260000/49257700/49257602/7b5947f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Guest rating: 8.8/10 (Excellent, 40 reviews) - Price: $74 nightly, $74 total, Nov 14 - Nov 15 - Review: Nice little hotel in a great location. Easy walk to the Plaza de Armas, by Amey Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://www.expedia.com/Hotel-Search?startDate=2026-11-27&endDate=2026-11-28®ionId=553248635975855328&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Mosopuquio Hotel Reviews ### [Sonesta Hotel Arequipa](https://www.expedia.com/Arequipa-Hotels-Sonesta-Hotel-Arequipa.h34550097.Hotel-Information) ![A modern building with a prominent glass facade and a unique triangular design.](https://images.trvl-media.com/lodging/35000000/34560000/34550100/34550097/2baefba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: City Towers, North Tower – Cerro Colorado, Arequipa, Arequipa, 4014, PE - Location: Cerro Colorado District - Star rating: 4/5 - Guest rating: 9.6/10 (226 reviews) - Review: Great location. Great breakfast bar and superb attention to detail. Customer service was good, very pleasant people. Will stay again upon my return to Arequipa., by denisse, November 5, 2026, rated 10/10 Excellent ### [Hotel El Lago by Luoxo](https://www.expedia.com/Arequipa-Hotels-BTH-Hotel-Arequipa-Lake.h1631543.Hotel-Information) ![A lakeside building with a reflection in the water, surrounded by trees.](https://images.trvl-media.com/lodging/2000000/1640000/1631600/1631543/03a47170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Pje Camino Al Molino S/n, Arequipa, Arequipa, 4012, PE - Location: Sabandía - Star rating: 3.5/5 - Guest rating: 8.4/10 (191 reviews) - Review: Beautiful property with a very helpful staff. The manager was very accomodating and friendly. Great food at the restaurant too., by Cory, August 19, 2026, rated 10/10 Excellent ### [Los Tambos - Boutique](https://www.expedia.com/Arequipa-Hotels-Los-Tambos.h3019439.Hotel-Information) ![A hotel room with a bed, bedside table, lamp, and a small table with a vase of sunflowers.](https://images.trvl-media.com/lodging/4000000/3020000/3019500/3019439/aeb0ea74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Puente Bolognesi 129, Arequipa, Arequipa, 4001, PE - Location: Historical Center - Star rating: 3.5/5 - Guest rating: 9.6/10 (562 reviews) - Review: My experience with Los Tambos started from the moment we booked via Expedia. Immediately, Vanessa followed up with a welcome note. When I inquired about tours to Colca Canyon, which we had trouble booking online without a Western Union transfer, she connected us with a guide and recommended a hotel in the canyon. Our experience on that excursion was incredible. Our experience at Los Tambos itself was also remarkable. Very competent, truly charming staff! When we checked-in, Diego welcomed..., by Danielle, December 22, 2015, rated 10/10 Excellent ### [Palla Boutique Hotel](https://www.expedia.com/Arequipa-Hotels-Palla-Boutique-Hotel.h14852197.Hotel-Information) ![A rooftop terrace with outdoor seating, a large umbrella, and a view of the cityscape.](https://images.trvl-media.com/lodging/15000000/14860000/14852200/14852197/115333ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Calle Puente Bolognesi 350, Arequipa, Arequipa, 04000, PE - Location: Historical Center - Star rating: 3.5/5 - Guest rating: 9.6/10 (132 reviews) - Review: The hotel is stunning, clean and comfortable with amazing views of the city and a great breakfast. I highly recommend it., by Silvia, October 24, 2026, rated 10/10 Excellent ### [Santa Marta Hotel Arequipa](https://www.expedia.com/Arequipa-Hotels-Santa-Marta-Boutique-Hotel.h14632207.Hotel-Information) ![A courtyard with stone flooring, potted plants, and outdoor seating.](https://images.trvl-media.com/lodging/15000000/14640000/14632300/14632207/be5a214e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Calle Santa Marta 207, Cercado, Arequipa, Arequipa, 04000, PE - Location: Historical Center - Star rating: 3/5 - Guest rating: 9.6/10 (25 reviews) - Review: Extremely beautiful common spaces. Rooms are more traditional, but overall a nice, clean environment. Kind and helpful staff., by Sara, July 22, 2026, rated 10/10 Excellent ### [Hampton by Hilton Arequipa](https://www.expedia.com/Arequipa-Hotels-Hampton-Inn-Arequipa.h63650278.Hotel-Information) ![A spacious dining area with stone walls, wooden furniture, and a variety of food and drink stations.](https://images.trvl-media.com/lodging/64000000/63660000/63650300/63650278/68280624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: A hotel , looks and smell like a brand new car , perfect location, , and excellent service .we highly recommend this place, not a 5 star hotel but really close to me, by Marcel, November 27, 2023, rated 10/10 Excellent ### [Hotel Boutique Villa Elisa](https://www.expedia.com/Arequipa-Hotels-Hotel-Boutique-Villa-Elisa.h10517032.Hotel-Information) ![A swimming pool with a view of a building complex and surrounding greenery.](https://images.trvl-media.com/lodging/11000000/10520000/10517100/10517032/ba5ca168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: It is the second time I stayed here. Simple, good service, nice people, by Luis Agustin, July 14, 2023, rated 10/10 Excellent ### [Los Tambos - Colonial](https://www.expedia.com/Arequipa-Hotels-LOS-TAMBOS-COLONIAL.h78462197.Hotel-Information) ![A spacious courtyard with wicker furniture and potted plants, featuring a stone floor and a high ceiling.](https://images.trvl-media.com/lodging/79000000/78470000/78462200/78462197/8b5ce5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: Very friendly staff, good facilities, great value, very convenient location, by Ivan, November 27, 2023, rated 10/10 Excellent ### [Casa Arequipa](https://www.expedia.com/Arequipa-Hotels-Casa-Arequipa.h1785043.Hotel-Information) ![A breakfast table with a variety of dishes, a vase with flowers, and a potted plant by a window with columns.](https://images.trvl-media.com/lodging/2000000/1790000/1785100/1785043/e8b9a5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Avendia Lima 409, Arequipa, Arequipa Region, PE - Location: Historical Center - Star rating: 3/5 - Guest rating: 9.4/10 (80 reviews) - Review: Very helpful staff., by John, November 6, 2026, rated 10/10 Excellent ### [Katari Hotel At Plaza de Armas](https://www.expedia.com/Arequipa-Hotels-Katari-Hotel-At-Plaza-De-Armas.h11828834.Hotel-Information) ![An outdoor dining area with tables and chairs, lanterns, and a view of a historic building with two towers and a mountain in the background.](https://images.trvl-media.com/lodging/12000000/11830000/11828900/11828834/2281f362.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Portal de la Municipalidad 126-128, Arequipa, 4001, PE - Location: Historical Center - Star rating: 3.5/5 - Guest rating: 9.4/10 (328 reviews) - Review: We loved our six night stay at Katari. The rooms were comfortable with traditional furniture and lovely linens. The location on the Plaza de Armas can’t be beat. The views from the rooftop restaurant and bar are spectacular at all times of the day, but especially at sunset, with the lights on the cathedral coming up and the sun turning the snow capped volcanoes pink. The only thing better are the staff, so kind, warm and responsive. Highly, highly recommend this place!, by Nancy, April 16, 2023, rated 10/10 Excellent ### [HOTEL AREQUIPA INN](https://www.expedia.com/Arequipa-Hotels-HOTEL-AREQUIPA-INN.h100496308.Hotel-Information) ![A hotel entrance with a glass door, a staircase leading to the upper floor, and potted plants along the pathway.](https://images.trvl-media.com/lodging/101000000/100500000/100496400/100496308/50469b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: Fantastic location to walk around the city., by Camilo, June 15, 2024, rated 10/10 Excellent ### [ARIQUEPAY HOTEL](https://www.expedia.com/Arequipa-Hotels-ARIQUEPAY-HOTEL.h98498516.Hotel-Information) ![A modern building with glass facades and a reflective pool.](https://images.trvl-media.com/lodging/99000000/98500000/98498600/98498516/efa8852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: This hotel is gorgeous, super clean, and perfectly located. The beds, pillows, and linens are luxurious, providing a true 5-star experience during our 5-night stay. We enjoyed drinks on the rooftop with stunning views of Plaza del Armas, and the pizza was delicious! Highly recommended! Tip: If you use the laundry service, be sure to separate your darks from whites, as they wash everything together., by Elisha, June 16, 2024, rated 10/10 Excellent ### [Hotel Santa Rosa](https://www.expedia.com/Arequipa-Hotels-Hotel-Santa-Rosa.h33638565.Hotel-Information) ![A bathroom with a shower, toilet, and a trash bin.](https://images.trvl-media.com/lodging/34000000/33640000/33638600/33638565/13251f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 206 Santa Catalina, Arequipa, Arequipa, 4001, PE - Location: Historical Center - Star rating: 3/5 - Guest rating: 9.2/10 (27 reviews) - Review: Excelente!!!!!!!, by Mirelis, October 22, 2026, rated 10/10 Excellent ### [HOTEL INKALMA SANTA MARTA](https://www.expedia.com/Arequipa-Hotels-INKALMA-CENTRO.h117059106.Hotel-Information) ![A modern living room with a flat-screen TV mounted on a wooden wall, a wooden bench, and a small table.](https://images.trvl-media.com/lodging/118000000/117060000/117059200/117059106/ddbeba91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Calle Santa Marta 208 B, Arequipa, Arequipa, 04001, PE - Location: Historical Center - Star rating: 2/5 - Guest rating: 9/10 (17 reviews) - Review: The staff was awesome! Super friendly and helpful. They allow you to leave your luggage there if you arrive early before check in. Only complaint was the water pressure in my room was pretty bad but overall I would stay again. They came in and cleaned everyday and brought fresh towels., by Sherry, July 17, 2026, rated 10/10 Excellent ### [Wyndham Costa del Sol Arequipa](https://www.expedia.com/Arequipa-Hotels-Wyndham-Costa-Del-Sol-Arequipa.h31717706.Hotel-Information) ![A hotel with a red facade, palm trees, and a pool.](https://images.trvl-media.com/lodging/32000000/31720000/31717800/31717706/f59baa17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: The Hotel is a little bit old. It is not well Lit at all. But the food is outstanding, the staff is amazing. With the exception of the older guy that works at night in the front desk, that guy didn’t seem like he wanted to be bothered at all. Besides that, everybody else went out of their way to help you in anyway they could. I have stayed in five star five diamond hotels, and this has been the best staff I have ever experienced. Well done. The staff is by far the star of all of this., by William, February 25, 2025, rated 10/10 Excellent ### [Hotel La Casa de Irma Arequipa](https://www.expedia.com/Arequipa-Hotels-La-Casa-De-Irma.h45595191.Hotel-Information) ![An outdoor dining area with tables and chairs, potted plants, and hanging lights.](https://images.trvl-media.com/lodging/46000000/45600000/45595200/45595191/c5fbbd5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: Fantastic hotel. I had a medical emergency during my stay and needed to visit the hospital. The staff and owner were extremely helpful in assisting me with this and allowing me to use the room after I had to return a bit beyond checkout time. Excellent laundry service also., by Cameron, September 2, 2026, rated 10/10 Excellent ### [Acolpacha - Tambo Boutique](https://www.expedia.com/Arequipa-Hotels-Acolpacha-Tambo-Boutique.h35729779.Hotel-Information) ![A bedroom with two beds, stone walls, a wooden floor, and a window.](https://images.trvl-media.com/lodging/36000000/35730000/35729800/35729779/d7044355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Historical Center - Review: Everybody and everything was wonderful We will be back, by zulma, October 28, 2026, rated 10/10 Excellent ## Frequently Asked Questions ### What is the best area to stay in Mosopuquio? The best area to stay in Mosopuquio is the central district surrounding the Plaza de Armas, which is the heart of the town. This area is the main hub for visitors, characterized by its well-preserved historic architecture and a relaxed pace. The Plaza de Armas itself is a central green space, often bustling with local activity, and is surrounded by important buildings like the local church and municipal offices. It's an excellent base for exploring the town on foot. For couples, this central district offers a pleasant and romantic setting. You'll find a selection of guesthouses and small hotels within easy walking distance of local eateries and craft shops. The evening strolls around the plaza provide a nice opportunity to experience the town's quiet charm. Solo travelers will also find the area around the Plaza de Armas to be very convenient. ### When is the best time to go to Mosopuquio? The best time to visit Mosopuquio is during the dry season, which runs from April to November. During these months, you'll experience clear skies and plenty of sunshine, making it ideal for exploring the natural beauty of the Arequipa Region. The weather is generally mild during the day, with cooler evenings, so packing layers is advisable. This period is superb for outdoor activities like hiking and visiting local attractions without the interruption of rain. For travelers looking to explore the natural landscapes, especially those interested in hiking or photography, the dry season offers the most favorable conditions. ### Can I cancel my hotel reservation on Expedia? You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mosopuquio. ### How much is the nightly rate at a Mosopuquio hotel? Prices for hotels in Mosopuquio often vary, but you can find a great deal from $23 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - [Lodging](?equalTargetTab=tab-0) - [Flights](?equalTargetTab=tab-1) - [Packages](?equalTargetTab=tab-2) - [Cars](?equalTargetTab=tab-3) - [Vacation Rentals](?equalTargetTab=tab-4) - [Things to Do](?equalTargetTab=tab-5) - [Characato Hotels](https://www.expedia.com/Characato-Hotels.d553248635973465290.Travel-Guide-Hotels) - [Casino Hotels in Arequipa](https://www.expedia.com/Arequipa-Hotels-Casino-Hotel.0-0-d410-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Arequipa](https://www.expedia.com/Arequipa-Hotels-Boutique-Hotel.0-0-d410-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hotels near Molino de Sabandia](https://www.expedia.com/Molino-De-Sabandia-Hotels.0-l553248621532464975-0.Travel-Guide-Filter-Hotels) - [Hotels with an Outdoor Pool in Arequipa](https://www.expedia.com/Arequipa-Hotels-Hotels-With-Outdoor-Pool.0-0-d410-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels) - 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