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Our top choices for Panajachel luxury hotels

Hotel Casa Palopó - Relais & Chateaux

4.0 star property
Santa Catarina Palopo
9.2 out of 10, Wonderful, (227)
"Love , an amazing place perfect museum was beautiful . "
United States
Jimmy
$438 nightly
The price is $526
Dec 12 - Dec 13
Total with taxes and fees
Hotel Casa Palopó - Relais & Chateaux

Kula Maya Boutique Hotel & Spa

5.0 star property
San Marcos La Laguna
9.6 out of 10, Exceptional, (114)
"The staff were very friendly and polite, and the food was delicious! "
United States
Yessica
$225 nightly
The price is $274
Jan 8 - Jan 9, 2026
Total with taxes and fees
Kula Maya Boutique Hotel & Spa

Art & Coffee

4.0 star property
Santa Cruz La Laguna
8.4 out of 10, Very Good, (5)
"I just want to say this hotel was the best i've stayed at. It was a top tier experience. I lost my money and my phone dropped in the water and they went out their way to get in contact with a boat taxi to get me back to the airport to make it to my flight. I'm so grateful for the experience. "
United States
Brooke
$15 nightly
The price is $19
Dec 12 - Dec 13
Total with taxes and fees
Art & Coffee

Casa Prana Hotel In Atitlan

4.0 star property
Santa Cruz La Laguna
9.4 out of 10, Exceptional, (50)
"One of the best places I’ve ever stayed. Grounds were beautiful, staff was on point and food was delicious."
United States
Abhilasha
$156 nightly
The price is $190
Dec 15 - Dec 16
Total with taxes and fees
Casa Prana Hotel In Atitlan

Sarnai

4.0 star property
San Marcos La Laguna
9.2 out of 10, Wonderful, (30)
"Staff is very courteous and very helpful and proactive to check our needs and following up things."
Mexico
Muraleedhar
$107 nightly
The price is $131
Dec 13 - Dec 14
Total with taxes and fees
Sarnai
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panajachel

Panajacheland its attractions for luxury travelers

In the picturesque town of Panajachel, luxury travelers can indulge in a variety of exclusive experiences. Begin your adventure by taking a private boat tour on Lake Atitlán, where you can marvel at the breathtaking views of the surrounding volcanoes and vibrant villages, all from the comfort of a beautifully appointed vessel. For those who appreciate art, a visit to the nearby town of San Juan La Laguna will take you through charming galleries showcasing local textiles and traditional crafts, offering a unique opportunity to engage with artisans. The stunning Reserva Natural Atitlán provides a serene escape, featuring lush hiking trails and the chance to observe exotic wildlife, perfect for families looking to blend adventure with relaxation. For an unforgettable culinary experience, dine at one of the upscale lakeside restaurants that offer gourmet Guatemalan cuisine, paired with fine wines and unparalleled views. As for accommodations, the upscale hotels along the lakefront provide not just luxurious amenities, but also a chance to unwind with spa services that embrace local traditions, ensuring a rejuvenating stay. This combination of natural beauty, cultural richness, and high-end hospitality makes Panajachel a must-visit for travelers seeking both comfort and adventure.

Find the best luxury hotels and resorts in Panajachel

For travelers seeking a luxurious retreat in the beautiful surroundings of Panajachel, Sololá, Guatemala, these hotels offer exquisite amenities and exceptional service. Each hotel promises a memorable stay that caters to the discerning guest.

Regis Hotel & Spa

  • Why it's great for a luxury retreat: Regis Hotel & Spa is a top choice for luxury travelers, a remarkable review rating of 9.0. Guests can indulge in in-room massages and enjoy premium bedding, making their stay both comfortable and rejuvenating.
  • Other amenities: The hotel features an onsite spa with hot springs, treatment rooms for various spa services, and a nearby shopping districts that allow for leisurely exploration. Guests can enjoy a patio area, daily housekeeping, and a yard for outdoor relaxation, ensuring an extensive luxury experience during their stay.
  • Nearby attractions: Lake Atitlán - 0.27 miles, Azul Maya Archaeological Museum - 0.24 miles

Hotel Atitlán

  • Why it's great for a luxury retreat: With a review rating of 8.8, Hotel Atitlán embodies luxury with its breathtaking lake views and cozy fireplaces in select rooms. The hotel provides guests with premium bedding for a restful night's sleep and a concierge to assist with tailored experiences during their stay.
  • Other amenities: This hotel features an outdoor pool with sun loungers, hot tub facilities for relaxation, and a stunning garden that enhances the tranquil atmosphere. Guests can enjoy onsite activities such as kayaking and fishing, along with convenient airport shuttle services and off-street parking for added ease.
  • Nearby attractions: Lake Atitlán - 0.05 miles, Azul Maya Archaeological Museum - 0.21 miles

Posada de Don Rodrigo Panajachel

  • Why it's great for a luxury retreat: Posada de Don Rodrigo Panajachel is known for its luxurious suites and has earned an impressive review rating of 8.8. This hotel offers guests a serene environment with an onsite spa and various massage options, enhancing their relaxation experience.
  • Other amenities: The hotel features an outdoor pool, early check-in, and late check-out options for convenience. Guests can also enjoy a beautiful garden area, full-service spa amenities, and free self-parking for a straightforward stay.
  • Nearby attractions: Lake Atitlán - 0.0 miles, La Galeria - 0.38 miles

Porta Hotel del Lago

  • Why it's great for a luxury retreat: Porta Hotel del Lago stands out as an ideal destination for luxury travelers with its stunning lake and mountain views, complemented by a guest review rating of 8.6. Guests can indulge in premium bedding and unwind in suites that feature deep soaking bathtubs, perfect for relaxation after a day of exploring.
  • Other amenities: The hotel offers a variety of features including a poolside bar for refreshing cocktails, an outdoor pool with sun loungers, a spa for rejuvenating treatments, and concierge services for personalized assistance. Additional offerings include airport transportation, a garden area for leisurely strolls, and nearby boat tours for scenic adventures on the lake.
  • Nearby attractions: Lake Atitlán - 0.1 miles, La Galeria - 0.23 miles

Top Panajachel Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Panajachel?
Use Expedia to help you arrange a flight to Quetzaltenango (AAZ-Los Altos) airport or La Aurora Intl. Airport (GUA) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Panajachel offers. Known for its gardens and volcanoes, Panajachel also has some interesting things to see and do including Lake Atitlán, so you may want to take in the local sights during your visit.
When can I expect good weather in Panajachel?
Planning for the weather is a good way to make your trip to Panajachel relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April with an average temp of 61°F, while the coldest months are January and December with an average of 60°F. The rainiest months in Panajachel are June, September, May, and August, with each month seeing an average of 19 inches of rainfall.
What's there to see and do in Panajachel?
Experience Panajachel and visit Lake Atitlán, Casa Cakchiquel Arts Center, and Panajachel Municipal Market. If you have some spare time during your trip, you might want to check out Museo Raúl Vasquéz and La Galeria.

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