Title: Top 10 Hotels in Santa Cruz from $120 - Competitive Prices | Expedia.com [Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d553248635926569460.Travel-Guide-VacationRentals)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d553248635926569460.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d553248635926569460.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 17 - Feb 18](https://www.expedia.com/Hotel-Search?regionId=553248635926569460&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 18 - Feb 19](https://www.expedia.com/Hotel-Search?regionId=553248635926569460&startDate=2026-02-18&endDate=2026-02-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=553248635926569460&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635926569460&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Exterior](https://images.trvl-media.com/lodging/104000000/103950000/103947200/103947104/145ce675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103950000/103947200/103947104/7e111ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/104000000/103950000/103947200/103947104/81f5af2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103950000/103947200/103947104/3556a4b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de huéspedes Chañarmuyo [](https://www.expedia.com/Chanarmuyo-Hotels-Casa-De-Huespedes-Chanarmuyo.h103947104.Hotel-Information) Chañarmuyo 10/10 Exceptional (1 review) "Nice little guesthouse in an amazing location between vines and mountains. Really nice dinner and wine tasting to a fair price!" ![Switzerland](https://a.travel-assets.com/egds/marks/flags/ch.svg) Dominik $120 nightly $120 total Feb 18 - Feb 19 [](https://www.expedia.com/Chanarmuyo-Hotels-Casa-De-Huespedes-Chanarmuyo.h103947104.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-03&endDate=2026-03-04®ionId=553248635926569460&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635926569460) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635926569460.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635926569460.Travel-Guide-Hotels) ## Top Santa Cruz Hotel Reviews ## More cheap stays in Santa Cruz ![HOSTEL La Casa de Li En](https://images.trvl-media.com/lodging/101000000/100410000/100402400/100402365/a1d8a486_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOSTEL La Casa de Li En 514 Guillermo Iribarren Chilecito Chilecito la rioja [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=100402365&PinnedHotelID=100402365&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/Chilecito-Hotels-HOSTEL-La-Casa-De-Li-En.h100402365.Hotel-Information) ![RUKA Apart ](https://images.trvl-media.com/lodging/91000000/90910000/90904400/90904369/82b7825f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### RUKA Apart Vidaleras Ramona y Lidia Barrios Chilecito La Rioja [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=90904369&PinnedHotelID=90904369&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/Chilecito-Hotels-RUKA-Apart.h90904369.Hotel-Information) ![Howard Johnson Chilecito Hotel & Casino](https://images.trvl-media.com/lodging/7000000/6710000/6704900/6704827/70325fc6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson Chilecito Hotel & Casino 19 February and Roque Lanus St, Chilecito La Rioja (province) [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=6704827&PinnedHotelID=6704827&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/Chilecito-Hotels-Howard-Johnson-Chilecito-Hotel-Casino.h6704827.Hotel-Information) ![Hostal Sisabel](https://images.trvl-media.com/lodging/47000000/46330000/46323600/46323544/242acc97_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Sisabel CALLE 12 DE OCTUBRE Tinogasta CATAMARCA [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=46323544&PinnedHotelID=46323544&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/Tinogasta-Hotels-Hostal-Sisabel.h46323544.Hotel-Information) ![Prisma Apart Hotel](https://images.trvl-media.com/lodging/21000000/20020000/20010900/20010876/ed7dc066_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Prisma Apart Hotel Buenos Aires 104 La Rioja [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=20010876&PinnedHotelID=20010876&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/La-Rioja-Hotels-Prisma-Apart-Hotel.h20010876.Hotel-Information) ![Eco Hostel Valle Fertil - Adults Only](https://images.trvl-media.com/lodging/19000000/18560000/18552200/18552199/dd2329b6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Eco Hostel Valle Fertil - Adults Only Mendoza 971 San Agustin de Valle Fertil San Juan [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=18552199&PinnedHotelID=18552199&HadPinnedHotel=true®ionId=553248635926569460) [](https://expedia.com/San-Agustin-De-Valle-Fertil-Hotels-Eco-Hostel-Valle-Fertil-Adults-Only.h18552199.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund? ### Where can I learn more about changing or cancelling my trip to Santa Cruz? ### What's the seasonal weather like in Santa Cruz? ## Explore a world of travel with Expedia - Lodging - Packages - More ways to book - [Chañarmuyo Hotels ](https://www.expedia.com/Chanarmuyo-Hotels.d553248635926569394.Travel-Guide-Hotels) - [Visit Chañarmuyo ](https://www.expedia.com/Chanarmuyo.dx553248635926569394) - [Book Hotels in Santa Cruz on Expedia.com.ar ](https://www.expedia.com.ar/Santa-Cruz-Hoteles.d553248635926569460.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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