Find hotels near Santa Fe River, from $60
Check prices for these dates
Compare 446 hotels close to Santa Fe River with room rates, reviews, and availability. Most hotels are fully refundable.

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
5.2 mi from Santa Fe River
10.0 out of 10, Exceptional, (146)
$139 nightly
The price is $153
Dec 8 - Dec 9
Total with taxes and fees

Vista Verde Farm Retreat
10.7 mi from Santa Fe River
9.6 out of 10, Exceptional, (12)
$155 nightly
The price is $174
Dec 8 - Dec 9
Total with taxes and fees

BlueGem Motel
6 mi from Santa Fe River
9.2 out of 10, Wonderful, (387)
$104 nightly
The price is $118
Dec 9 - Dec 10
Total with taxes and fees

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
10.9 mi from Santa Fe River
9.4 out of 10, Exceptional, (1003)
$113 nightly
The price is $127
Dec 21 - Dec 22
Total with taxes and fees

Hampton Inn & Suites Alachua I-75
11.2 mi from Santa Fe River
9.4 out of 10, Exceptional, (471)
$95 nightly
The price is $107
Jan 1 - Jan 2, 2026
Total with taxes and fees

High Springs Country Inn
5.8 mi from Santa Fe River
8.4 out of 10, Very Good, (16)
$64 nightly
The price is $73
Dec 10 - Dec 11
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Santa Fe River Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
10/10 Excellent
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