Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Best Resorts in Santee

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13
In one month
Sep 25 - Sep 27
In two months
Oct 23 - Oct 25
No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

Breakfast area

1. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (933 reviews)
"Quick stay, hotel was clean and safe. Staff was super helpful and friendly."
United States
Vicky L
$98 nightly
The price is $108
Sep 13 - Sep 14
Total with taxes and fees
Tru By Hilton Santee
Room, 2 Queen Beds, Non Smoking

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,484 reviews)
"Very quiet, dog friendly, clean, breakfast included."
United States
Yomerys
$75 nightly
The price is $83
Aug 31 - Sep 1
Total with taxes and fees
Baymont by Wyndham Santee
Breakfast area

3. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,002 reviews)
"The room was clean, bed was comfortable, and staff was kind! It was a great stopping point on our way to Florida."
United States
Cameron
$123 nightly
The price is $137
Sep 7 - Sep 8
Total with taxes and fees
Hampton Inn Santee-I-95
Exterior

4. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,003 reviews)
"Breakfast was good, staff very helpful."
United States
Bonnie
$111 nightly
The price is $123
Sep 6 - Sep 7
Total with taxes and fees
Best Western Plus Santee Inn
Property amenity

5. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,006 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
$130 nightly
The price is $144
Sep 15 - Sep 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
Children's activities

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,001 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
$105 nightly
The price is $117
Sep 6 - Sep 7
Total with taxes and fees
Holiday Inn Santee by IHG
Room

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,000 reviews)
"Was a good place to stay"
United States
santa
$101 nightly
The price is $112
Sep 20 - Sep 21
Total with taxes and fees
Comfort Inn & Suites Santee
Room

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (771 reviews)
"The staff was very helpful and respectful."
United States
Mark
$64 nightly
The price is $71
Aug 31 - Sep 1
Total with taxes and fees
Travelodge by Wyndham Santee
Lobby

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (473 reviews)
"An older fecility but certainly well maintained. Loved Mr. Patel!"
United States
William
$64 nightly
The price is $71
Sep 6 - Sep 7
Total with taxes and fees
Super 8 by Wyndham Santee/I-95
Breakfast area

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (584 reviews)
"It was very clean-might need a few updates to the bathroom tho."
United States
Clara
$59 nightly
The price is $66
Sep 20 - Sep 21
Total with taxes and fees
Quality Inn & Suites Santee I-95
Room

11. Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (316 reviews)
"The shops and restaurants are all within walking distance & it is only 4.2 miles to the Palmetto Resort where my sister & I met up with my nephew& his wife."
United States
Dorothy
$58 nightly
The price is $66
Sep 27 - Sep 28
Total with taxes and fees
Econo Lodge Santee
Living area

12. Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (46 reviews)
"This was our first long trip with our dog and she loved the place! Fenced in yard and home was cozy and dog friendly. Loved the farmhouse style and large bedrooms and baths. "
United States
Lori B.
$284 nightly
The price is $316
Sep 8 - Sep 9
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Property grounds

13. Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"This is an amazing place to stay! Wake up in a beautiful place with stunning views and huge kitchen! Multiple boat docks that you can see turtles, alligators, fish from! Highly recommend "
United States
Hope M.
$383 nightly
The price is $425
Sep 20 - Sep 21
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Terrace/patio

14. LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.8 out of 10, Excellent, (6 reviews)
"Great stay no complaints. "
United States
Quantrel P.
$413 nightly
The price is $458
Sep 19 - Sep 20
Total with taxes and fees
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Living area

15. Lake Marion Condo, Boat Slip Included, Pet Friendly

Lake Marion Condo, Boat Slip Included, Pet Friendly
Santee
$315 nightly
The price is $350
Aug 31 - Sep 1
Total with taxes and fees
Lake Marion Condo, Boat Slip Included, Pet Friendly
Lobby

16. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (590 reviews)
"The price rate was great"
United States
Stevenson
$67 nightly
The price is $75
Sep 27 - Sep 28
Total with taxes and fees
Ramada by Wyndham Santee I-95
Lobby lounge

17. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (820 reviews)
"Amazing hotel. Always my go to whenever I am staying in Orangeburg. Highly recommended!"
United States
Percy
$101 nightly
The price is $112
Aug 31 - Sep 1
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg
Panoramic Tent | Lake view

18. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (98 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
$72 nightly
The price is $80
Aug 31 - Sep 1
Total with taxes and fees
Bells Marina & Resort
Breakfast area

19. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
2.0 star property
Orangeburg
5.6 out of 10, (737 reviews)
"The only thing about the property is that there are still some renovations going on. But the room is self was very clean, the remodeling is very nice and there are no bugs. The staff is also very pleasant and friendly! I would definitely stay there again in the future."
United States
Amanda
$58 nightly
The price is $65
Sep 6 - Sep 7
Total with taxes and fees
Red Roof Inn Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Love the location very friendly and clean. I love they have high security on site"
fern 1-night trip
Posted 19 hours ago
Travelodge by Wyndham Santee

Find out more about Santee

Santee Resorts information

Number of reviews
5,048
Accommodation
1 Resorts
Lowest Price
$65
Highest Price
$458

Frequently asked questions

What can I expect from a resort vacation in Santee?
You deserve a vacation, and a resort is the perfect place to treat yourself to the services and amenities you need for a relaxing trip to Santee. One of the comfortable resorts in the surrounding area might be just what you're searching for, whether you want a luxurious suite, shopping possibilities, or nightly entertainment options.
What's a favorite resort in Santee?
Here's our top-rated Santee resort: Waterfront Condo on Lake Marion - Golf resort. Features a fitness center.
How many resorts will I find in Santee?
Choose among Expedia's 5 resort hotels in Santee where you'll find onsite spas, beautiful rooms, and more.
What can I do in Santee?
Travelers enjoy the golfing and other activities in Santee, and also have good things to say about the dining options here. If you brought your golf clubs, you can hit the links at Santee Cooper Country Club or Santee National Golf Club. Additional attractions in the area include Santee State Park and Lake Marion.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's the best way to get to and around Santee?
Fly into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the heart of the city. If you'd like to venture out around the area, you may want to rent a car for your trip.

Explore a world of travel with Expedia