Seneca Vacation Rentals

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Vacation Rentals in Seneca

Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Cabin in Seneca

2.0 star property
9.8 out of 10, Exceptional, (46)
"The place was absolutely magnificent."
United States
David
$129 nightly
The price is $142
Dec 1 - Dec 2
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Smart TV, fireplace
Enjoy one of our RV units son less of a headache for you this vacation!

Mobile Home in Seneca

7.0 out of 10, Good, (2)
"Very nice camper in a good location close to Clemson. Perfect for attending games. Took us 10-15 minites to get to stadium. All on back roads.Host was responsive to messages and requests. Only thing I would recommend to host is to reach out a couple days before just to give you check in details. Check in was very simple, but i had to reach to them to get the details. Would definitely stay here again!!"
United States
Hunter P.
$139 nightly
The price is $153
Nov 30 - Dec 1
Total with taxes and fees
Enjoy one of our RV units son less of a headache for you this vacation!
Property grounds
Cozy Clemson TIny House Cabin

Cabin in Seneca

2.0 star property
$172 nightly
The price is $189
Nov 23 - Nov 24
Total with taxes and fees
Cozy Clemson TIny House Cabin
Fridge, microwave, oven, stovetop
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Camping in Seneca

10.0 out of 10, Exceptional, (12)
"Very nice, great surroundings. Everyone was nice and pleasant to meet while there. Great place to stay for Clemson games!!! "
United States
Glenda
$183 nightly
The price is $201
Nov 24 - Nov 25
Total with taxes and fees
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Private kitchen
The Clemson Cottage - 3.6 mi. to Memorial Stadium

Vacation Home in Seneca

10.0 out of 10, Exceptional, (12)
"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "
United States
Mandy H.
$359 nightly
The price is $395
Nov 23 - Nov 24
Total with taxes and fees
The Clemson Cottage - 3.6 mi. to Memorial Stadium
Property grounds
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

Vacation Home in Seneca

10.0 out of 10, Exceptional, (3)
"Great place with a lot close by"
United States
Aldor D.
$247 nightly
The price is $271
Dec 12 - Dec 13
Total with taxes and fees
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Fridge, microwave, oven, stovetop
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Vacation Home in Downtown

2.0 star property
10.0 out of 10, Exceptional, (16)
"The owner, John, is an exceptional host and made our stay even more enjoyable. The location is so convenient to Downtown Seneca restaurants and grocers. We would recommend this home as a fair value. "
United States
Joann H.
$300 nightly
The price is $325
Nov 23 - Nov 24
Total with taxes and fees
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Terrace/patio
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Vacation Home in Seneca

6.0 out of 10, (1)
"The tiny house was clean, well-appointed, and sits on a nice setting. The host responded late on Sat, to a problem from the previous guests, so we appreciated that.Must mention that the loft bedroom is not practical for an adult since you cannot stand/no storage. Yes, there is a water/lake view, but since the dock is 1/2 out of the water, it is more like a stream."
United States
Gary S.
$233 nightly
The price is $256
Nov 24 - Nov 25
Total with taxes and fees
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Fridge, microwave, oven, stovetop
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Vacation Home in Serenity Bay

9.8 out of 10, Exceptional, (129)
"A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!"
United States
stacy s.
$562 nightly
The price is $618
Dec 1 - Dec 2
Total with taxes and fees
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Microwave, oven, stovetop, dishwasher
The Big Golf House- 10 miles to Clemson

Vacation Home in Seneca

$513 nightly
The price is $557
Nov 24 - Nov 25
Total with taxes and fees
The Big Golf House- 10 miles to Clemson
Fridge, microwave, oven, stovetop
Johnsons Cove - Lakefront Retreat With EV Charger

Vacation Home in Seneca

10.0 out of 10, Exceptional, (1)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
$663 nightly
The price is $708
Nov 23 - Nov 24
Total with taxes and fees
Johnsons Cove - Lakefront Retreat With EV Charger
Smart TV, video games
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Vacation Home in Seneca

9.6 out of 10, Exceptional, (8)
"Owner was on point with contact prior to arrival and during stay. Check in was super easy and property was clean and decorated nicely. Everything that we needed was already at the house. There is a marina close by with restaurant also."
United States
Benjamin J.
$723 nightly
The price is $766
Nov 23 - Nov 24
Total with taxes and fees
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
TV, stereo
Timber Trail Estate: Stunning Views + Waterfront

Vacation Home in Seneca

2.0 star property
6.4 out of 10, (5)
"Main floor was clean but basement and loft, cleaners missed a lot. It was very dusty with lots of cobwebs. Cleaners have missed a lot of places over and over again. The downstairs deck was full of pollen and so dirty we couldn’t sit out there. Wish there was an umbrella on top deck- no shade or cover when rains. Wish there was somewhere to put suitcases but w no closet space and no dresser tops, suitcases were all over floors. Was just hoping for a cleaner space for what we paid. Overall it was...
United States
Kristen F.
$438 nightly
The price is $497
Nov 24 - Nov 25
Total with taxes and fees
Timber Trail Estate: Stunning Views + Waterfront
Smart TV
The Pendle-Tin

Mobile Home in Pendleton

9.8 out of 10, Exceptional, (9)
"Loved that it was 10 minutes from Clemson; yet felt so remote in a great way. Wanted a break from the college bustle."
United States
Lynette
$185 nightly
The price is $205
Nov 27 - Nov 28
Total with taxes and fees
The Pendle-Tin
Exterior
Charming 3-bedroom mobile home with WiFi and AC close to Lake Hartwell

Mobile Home in Anderson

2.0 star property
9.2 out of 10, Wonderful, (5)
"Great place to stay!"
United States
Shasta N.
$275 nightly
The price is $305
Nov 23 - Nov 24
Total with taxes and fees
Charming 3-bedroom mobile home with WiFi and AC close to Lake Hartwell
Pool
Glamping with a partial lake view, 30 minutes to Clemson University

Mobile Home in Westminster

9.4 out of 10, Exceptional, (14)
"The camper was very clean and the set up was very nice. Didn’t have a view of the lake, but all in all had a very nice stay. "
United States
Scott S.
$193 nightly
The price is $212
Nov 24 - Nov 25
Total with taxes and fees
Glamping with a partial lake view, 30 minutes to Clemson University
Standard Cabin, Courtyard View | Premium bedding, in-room safe, laptop workspace, free WiFi
Carolina Camp Cedar

Cabin in Pickens

3.5 star property
$179 nightly
The price is $199
Nov 23 - Nov 24
Total with taxes and fees
Carolina Camp Cedar
Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix
Clemson Memorabilia House

Cottage in Clemson

3.0 star property
9.8 out of 10, Exceptional, (8)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
$208 nightly
The price is $231
Nov 23 - Nov 24
Total with taxes and fees
Clemson Memorabilia House
Property grounds
Tiny House - Slice of Heaven Walhalla

Cottage in Walhalla

9.4 out of 10, Exceptional, (30)
"Nice serene location"
United States
GAIL
$188 nightly
The price is $206
Nov 23 - Nov 24
Total with taxes and fees
Tiny House - Slice of Heaven Walhalla
Outdoor dining
Broyles Landing Cottage at Lake Hartwell SC

Cottage in Townville

10.0 out of 10, Exceptional, (15)
"Easy check in, the place was stocked with awesome snacks we werent expecting. The cots were very comfortable. "
United States
Damian D.
$209 nightly
The price is $232
Nov 23 - Nov 24
Total with taxes and fees
Broyles Landing Cottage at Lake Hartwell SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

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Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

10/10 Excellent
"Room seems very clean but smells like it was smoked in and the smell covered up. All else is very good."
Mike 1-night trip
Posted 2 days ago
Days Inn by Wyndham Seneca / Clemson Area

Find out more about Seneca

Everything you need to know about Seneca vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Seneca vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Seneca vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Seneca vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Seneca. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Seneca in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $142 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Seneca rentals

At Expedia, we put the best Seneca vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Seneca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Seneca vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Seneca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals close to popular attractions in Seneca, or you can select a secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.: This highly rated vacation home rental in Seneca is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Seneca include 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub! and Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson..

How many vacation rentals are there in Seneca?

Choose from 199 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Lake Keowee and Lake Hartwell are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Seneca Historic District are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.