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Find Southeast Missouri motels from $55

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Motels in Southeast Missouri

Lobby
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1009)
"Check in was smooth and facilities are excellent "
United States
Hector
$76 nightly
The price is $80
Dec 7 - Dec 8
Total with taxes and fees
Motel 6 Poplar Bluff, MO
Exterior
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2.0 star property
Farmington
8.0 out of 10, Very Good, (610)
"Clean, friendly staff, quiet"
United States
Stacy
$55 nightly
The price is $63
Dec 3 - Dec 4
Total with taxes and fees
Super 8 by Wyndham Farmington
BBQ/picnic area
Current River Inn

Current River Inn

3.0 star property
Van Buren
8.2 out of 10, Very Good, (164)
"The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!"
United States
Thad
$98 nightly
The price is $107
Dec 5 - Dec 6
Total with taxes and fees
Current River Inn
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 star property
Portageville
8.0 out of 10, Very Good, (723)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
$59 nightly
The price is $64
Dec 7 - Dec 8
Total with taxes and fees
New Orleans Inn Portageville
Property entrance
Madison Inn Lodge

Madison Inn Lodge

2.5 star property
Fredericktown
7.6 out of 10, Good, (296)
"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
$78 nightly
The price is $85
Dec 3 - Dec 4
Total with taxes and fees
Madison Inn Lodge
Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets
Town House Inn

Town House Inn

2.5 star property
Jackson
7.6 out of 10, Good, (422)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
$63 nightly
The price is $69
Jan 1 - Jan 2, 2026
Total with taxes and fees
Town House Inn
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (117)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
$56 nightly
The price is $64
Dec 3 - Dec 4
Total with taxes and fees
Country Yard Inn and Suite
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

2.0 star property
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
United States
David
$60 nightly
The price is $67
Dec 3 - Dec 4
Total with taxes and fees
Eagle Inn Charleston
Signature Room | Terrace/patio
Black River Motel and Restaurant

Black River Motel and Restaurant

2.0 star property
Lesterville
8.4 out of 10, Very Good, (34)
"This has been a great place to stay when we are traveling through Reynolds County MO."
United States
Michael
$99 nightly
The price is $105
Dec 29 - Dec 30
Total with taxes and fees
Black River Motel and Restaurant
Desk, laptop workspace, free WiFi, bed sheets
Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO

2.0 star property
Bonne Terre
6.8 out of 10, (25)
"Quick check-in; plenty of parking and the room was easy to find. Convenient, clean, casual, can’t complain. "
United States
Tim
$53 nightly
The price is $58
Dec 8 - Dec 9
Total with taxes and fees
Motel 6 Bonne Terre, MO
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter

Econo Lodge Dexter

2.0 star property
Dexter
6.8 out of 10, (250)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
$59 nightly
The price is $67
Jan 1 - Jan 2, 2026
Total with taxes and fees
Econo Lodge Dexter
Exterior
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2.0 star property
Perryville
8.4 out of 10, Very Good, (935)
"The room was spotless, and the staff was extremely patient. Each one was very helpful. It was easy to get a good night's sleep - the building was very quiet."
United States
Cynthia
$63 nightly
The price is $72
Dec 25 - Dec 26
Total with taxes and fees
Super 8 by Wyndham Perryville
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
$73 nightly
The price is $82
Dec 7 - Dec 8
Total with taxes and fees
Town House Inn Cape Giradreau
Exterior
OYO Hickory House Inn

OYO Hickory House Inn

2.5 star property
Dexter
5.4 out of 10, (128)
"Courteous staff"
United States
GEORGE
$50 nightly
The price is $55
Dec 31 - Jan 1, 2026
Total with taxes and fees
OYO Hickory House Inn
Property entrance
Rosener's Inn and banquet center

Rosener's Inn and banquet center

2.0 star property
Park Hills
5.0 out of 10, (48)
"Not the cleanest place I've ever stayed, but you get what you pay for. If you expect pristine rooms, comfortable beds, clean towels, blankets and sheets, coffee makers, refrigerators and microwaves for $50 a night, you will be terribly disappointed. There is a reason the rooms aren't $150 per night. "
United States
Brock
$87 nightly
The price is $96
Jan 2 - Jan 3, 2026
Total with taxes and fees
Rosener's Inn and banquet center
Lobby
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre

2.0 star property
Bonne Terre
7.0 out of 10, Good, (534)
"Fresh an always ready first thing in mornings"
United States
Dj
$50 nightly
The price is $55
Dec 9 - Dec 10
Total with taxes and fees
Super 8 by Wyndham Bonne Terre
Standard Room, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board
Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi

2.0 star property
Potosi
7.0 out of 10, Good, (378)
"The room was very good for the price."
United States
Benjamin
$55 nightly
The price is $60
Dec 3 - Dec 4
Total with taxes and fees
Super 8 by Wyndham Potosi
In-room safe, desk, free WiFi, bed sheets
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2.0 star property
Poplar Bluff
6.6 out of 10, (621)
"The lady at the front was very nice. "
United States
Travis
$54 nightly
The price is $60
Dec 14 - Dec 15
Total with taxes and fees
Super 8 by Wyndham Poplar Bluff Missouri
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
United States
Lana
$59 nightly
The price is $65
Dec 3 - Dec 4
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
In-room safe, desk, iron/ironing board, free cribs/infant beds
Super 8 by Wyndham West Plains

Super 8 by Wyndham West Plains

2.0 star property
West Plains
7.4 out of 10, Good, (458)
"Great place to stay."
United States
Andrew
$64 nightly
The price is $72
Jan 1 - Jan 2, 2026
Total with taxes and fees
Super 8 by Wyndham West Plains
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"I liked how comfortable the beds and pillows were."
Christine 4-night trip
Posted 2 days ago
Pear Tree Inn Cape Girardeau Near the Medical Center

Find out more about Southeast Missouri

Southeast Missouri Motels information

Number of reviews
7,582
Accommodation
26 Motels
Lowest Price
$55
Highest Price
$107

Frequently asked questions

What is the nightly rate for a motel in Southeast Missouri?
You can find a great deal from $55 on Southeast Missouri motels with Expedia. Typically, prices are higher during popular times – like weekends and holidays – while staying midweek is often cheaper. To find the best nightly rates on Southeast Missouri motels, try to be flexible with travel dates, and sort search results by price from low to high.
Is it better to stay in a Southeast Missouri motel or hotel?
Motels and Hotels have different perks. When you stay at a motel, you're likely to find free parking and an outdoor pool. Staying overnight at a motel, can be handy when requiring easy road access. You'll often have access to your room from outside, and directly from the parking lot. Hotels generally have room access from inside the building. Motels are also often less expensive than hotels. The word "motel" was coined in 1925 by the owner of the Milestone Mo-Tel in San Luis Obispo, California.

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