$243 Cheap Flights from Pittsburgh (PIT) to Florence (FLO)

View $243 flight on Wed, Apr 29, 2026Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Pittsburgh to Florence (PIT-FLO)

Prices were available within the past 7 days and start at $243 for one-way flights and $434 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, May 29 - Tue, Jun 2
PIT
Pittsburgh
FLO
Florence
$434 Roundtrip, found 5 days ago
$434
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, May 29 from Pittsburgh to Florence, returning Tue, Jun 2, priced at $434 found 5 days ago
American Airlines
Wed, Oct 14 - Wed, Oct 21
PIT
Pittsburgh
FLO
Florence
$473 Roundtrip, found 3 days ago
$473
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 14 from Pittsburgh to Florence, returning Wed, Oct 21, priced at $473 found 3 days ago
American Airlines
Wed, Apr 29 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$475 Roundtrip, found 4 days ago
$475
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 29 from Pittsburgh to Florence, returning Sat, May 2, priced at $475 found 4 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
PIT
Pittsburgh
FLO
Florence
$485 Roundtrip, found 3 days ago
$485
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Apr 30 from Pittsburgh to Florence, returning Sat, May 9, priced at $485 found 3 days ago
American Airlines
Wed, May 20 - Mon, May 25
PIT
Pittsburgh
FLO
Florence
$488 Roundtrip, found 3 days ago
$488
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, May 20 from Pittsburgh to Florence, returning Mon, May 25, priced at $488 found 3 days ago
American Airlines
Wed, Apr 29 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$492 Roundtrip, found 4 days ago
$492
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 29 from Pittsburgh to Florence, returning Sat, May 2, priced at $492 found 4 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
PIT
Pittsburgh
FLO
Florence
$503 Roundtrip, found 3 days ago
$503
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Apr 30 from Pittsburgh to Florence, returning Sat, May 9, priced at $503 found 3 days ago
American Airlines
Sat, Aug 1 - Thu, Aug 6
PIT
Pittsburgh
FLO
Florence
$507 Roundtrip, found 2 days ago
$507
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug 1 from Pittsburgh to Florence, returning Thu, Aug 6, priced at $507 found 2 days ago
American Airlines
Wed, Apr 29 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$512 Roundtrip, found 4 days ago
$512
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 29 from Pittsburgh to Florence, returning Sat, May 2, priced at $512 found 4 days ago
American Airlines
Mon, May 18 - Fri, Jun 19
PIT
Pittsburgh
FLO
Florence
$520 Roundtrip, found 1 day ago
$520
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, May 18 from Pittsburgh to Florence, returning Fri, Jun 19, priced at $520 found 1 day ago

Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $586
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $586

Frequently asked questions

How much does a flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) cost?
You can find cheap one-way flights from $243 and cheap return flights from $434 Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) with Expedia. One-way flights typically cost between $352 and $457, and return flights often range between $518 and $1345. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
The cheapest month to fly from PIT to FLO is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
Enter PIT to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Pittsburgh Intl. (PIT) to Florence Regional (FLO), with round-trip tickets starting from around $474 with a layover in O'Hare Intl. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
To find a cheap flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
The earliest flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) usually departs at around 6:00 AM, operated by American Airlines. This is a seasonal service available in December. An early flight allows you to arrive in Florence with plenty of time to explore the area. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
The most popular departure times for flights from Pittsburgh, PA (PIT) to Florence, SC (FLO) are in the early morning, from 6am to 9am. About 42% of passengers prefer this time window. American Airlines offers flights during this window. This timing is favored as it allows you to start your day early and make the most of your time in Florence.
How long does it take to fly from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
Flights from PIT to FLO with one stop typically take around 4 hours 20 minutes, covering approximately 436 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
Select the "Business class" and "First class" filters when looking for PIT to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) flight with Expedia?
It's easy to earn miles on a Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Florence from Pittsburgh Intl. (PIT)?
From Pittsburgh Intl. (PIT), you can fly into Peretola (FLR) and Florence Regional (FLO) in Florence. Some flights may connect through major hubs like Washington Dulles Intl. (IAD), O'Hare Intl. (ORD), Liberty Intl. (EWR) before reaching Florence. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) at the last minute?
Typically, booking a last minute flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package?
Securing a Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional)?
If you booked your Pittsburgh, PA (PIT-Pittsburgh Intl.) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Pittsburgh Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$434
Distance
436 mi

*Flight schedules are subject to change.

*Available to One Key members.

 

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