Santa Cruz Island Adventure Vacations

Book a Adventure Hotel + Flight or Car together to unlock savings

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Top Adventure vacation packages in Santa Cruz Island

Price found within the past 48 hours. Click for updated prices.
Blu Galapagos Sustainable Waterfront Lodge
Finch Bay Galapagos Hotel
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3 Night Adventure vacations in Santa Cruz Island

Price found within the past 48 hours. Click for updated prices.
Blu Galapagos Sustainable Waterfront Lodge
Finch Bay Galapagos Hotel
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See all available trips from Columbus to Santa Cruz Island
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4 Night Adventure vacations in Santa Cruz Island

Price found within the past 48 hours. Click for updated prices.
Hotel el descanso del Guia
Angermeyer Waterfront Inn
 Twin Hotel Galapagos
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See all available trips from Columbus to Santa Cruz Island
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Find awesome Santa Cruz Island adventure vacations

How can I book the best Santa Cruz Island adventure trips?

Choose your own adventure in Santa Cruz Island, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun.

How can I plan the perfect Santa Cruz Island family adventure vacation?

Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Santa Cruz Island. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning.

Can I book all-inclusive Santa Cruz Island adventure vacation packages?

By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway.

Why should I book a Santa Cruz Island adventure vacation for couples?

Book a Santa Cruz Island couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond.

How can I find the best deals on adventure packages in Santa Cruz Island?

It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals.

Can I book an adventure vacation package in Santa Cruz Island with free cancellation and/or flexible dates?

Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility.

Why should I book a Santa Cruz Island adventure trip with Expedia?

Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A.

Top Adventure Santa Cruz Island Hotels

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos
  • 14 min walk from Charles Darwin Research Station
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (122 reviews)
Enio is a great asset for this hotel. He was very helpful and friendly. The hotel itself is very quiet, clean and comfortable.

Reviewed on Oct 4, 2025

Angermeyer Waterfront Inn
Ariana´S Galapagos Hostal

Ariana´S Galapagos Hostal

3 out of 5
Avenida Galapagos #806 y Pasaje #2, Puerto Ayora
  • 17 min walk from Charles Darwin Research Station
Stay at this 3-star B&B in Puerto Ayora. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the property condition in our reviews. Popular ...
8.6/10 Excellent! (55 reviews)
The manager spoke english. He was very friendly and helpful.

Reviewed on Mar 4, 2025

Ariana´S Galapagos Hostal
Maytenus Galapagos

Maytenus Galapagos

2.5 out of 5
Calle Petrel y Scalesia, Puerto Ayora, Santa Cruz
  • 8 min walk from Charles Darwin Research Station
Stay at this aparthotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Fishing Piers and Charles Darwin ...
OLD FAR AWAY FROM EVERYTHING
Very far from Restaurants,stores and Main Street. OVERPRICED. OLD. Got a different apartment from the one booked. No taxi in town knows the place. Managed by old couple. Will not recommend it. The

Reviewed on May 15, 2019

Maytenus Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.