Find 4 Star Hotels in Syracuse from $97

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Our top choices for Syracuse 4-star hotels

Algila' Ortigia Charme Hotel

4.0 star property
Ortigia
9.6 out of 10, Exceptional, (905)
"The breakfast was delicious, the staff impeccable and the room delightful. All in all an excellent stay which I would wholeheartedly recommend. "
United Kingdom
Sarah
$186 nightly
The price is $216
Dec 10 - Dec 11
Total with taxes and fees
Algila' Ortigia Charme Hotel

Mercure Siracusa Prometeo

4.0 star property
Neapolis
9.0 out of 10, Wonderful, (485)
"Excellent central location. Comfortable rooms with safe and walk in shower. Great staff helpful, polite, professional and friendly. Had a very relaxing time."
United Kingdom
Persefoni
$102 nightly
The price is $128
Dec 14 - Dec 15
Total with taxes and fees
Mercure Siracusa Prometeo

Grand Hotel Villa Politi

4.0 star property
Grottasanta
8.6 out of 10, Excellent, (941)
"Wonderful hotel, nice area and great buffet breakfast"
United States
paula
$101 nightly
The price is $115
Dec 13 - Dec 14
Total with taxes and fees
Grand Hotel Villa Politi

Eureka Palace Hotel Spa Resort

4.0 star property
Syracuse
8.0 out of 10, Very Good, (324)
"It’s amazing if you have your own car and are able to move around. Breakfast is good, the rooms are a little old but they are comfortable and clean, the staff is very kind. I’ve stayed at this hotel for the last 4 or 5 summer vacations. It’s an amazing place to stay if you want to explore the area."
United States
Giovanni
$85 nightly
The price is $97
Dec 16 - Dec 17
Total with taxes and fees
Eureka Palace Hotel Spa Resort

Hotel Parco delle Fontane

4.0 star property
Tiche
9.2 out of 10, Wonderful, (281)
"Pool was excellent and the surrounding gardens superb "
United States
ROBERT
$94 nightly
The price is $107
Dec 13 - Dec 14
Total with taxes and fees
Hotel Parco delle Fontane

UNA HOTELS One Siracusa

4.0 star property
Grottasanta
8.6 out of 10, Excellent, (540)
"Very nice hotel, nice sized rooms, great staff that was very helpful."
United States
Mark
$130 nightly
The price is $148
Dec 11 - Dec 12
Total with taxes and fees
UNA HOTELS One Siracusa

Palazzo Artemide - VRetreats, SLH Collection

4.0 star property
Ortigia
9.4 out of 10, Exceptional, (659)
"Great hotel"
United States
Caterina
$173 nightly
The price is $202
Jan 7 - Jan 8, 2026
Total with taxes and fees
Palazzo Artemide - VRetreats, SLH Collection

Grande Albergo Alfeo

4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (651)
"The room was nice the location convenient. No view to speak of but centrally located"
Canada
Eric
$93 nightly
The price is $106
Dec 15 - Dec 16
Total with taxes and fees
Grande Albergo Alfeo

Hotel Palazzo Cavalieri

4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (38)
"The location of this hotel is ideal! Directly between the train station and Ortigia. Easy walking to many different restaurants. We very much enjoyed our short stay here and the daily activities hosted by the Hotel. My only iffy thing was the tiles in the bathroom (the shower specifically) seemed a bit older and maybe not as cleanly as it could be, but all in all the room was quite nice. "
Canada
Lindsay
$103 nightly
The price is $117
Dec 14 - Dec 15
Total with taxes and fees
Hotel Palazzo Cavalieri

Charme Hotel Henry's House

4.0 star property
Ortigia
9.6 out of 10, Exceptional, (322)
"Great location. Very friendly and helpful staff. Nice breakfast."
United States
Alan
$270 nightly
The price is $309
Dec 28 - Dec 29
Total with taxes and fees
Charme Hotel Henry's House

Hotel Villamare

4.0 star property
Syracuse
9.2 out of 10, Wonderful, (109)
"All staff were very professional and friendly, took time to understand our needs. Breakfast was excellent, good range. Evening meals good but limited menu. Good location near a very nice beach and easy to get around by car"
United Kingdom
Colin
Hotel Villamare

Hotel Relax

4.0 star property
Epipoli
8.2 out of 10, Very Good, (33)
"Camera spaziosa e pulita, dintorni silenziosi, personale molto attento agli ospiti, gentile e cordiale, colazione a buffet con molte opzioni abbondanti, puntuali."
Italy
Gabriella
$95 nightly
The price is $109
Jan 9 - Jan 10, 2026
Total with taxes and fees
Hotel Relax

Aretusa Palace Hotel

4.0 star property
Syracuse
6.8 out of 10, (98)
"Ruggine sui tetti del bagno. "
Italy
Vincenzo
Aretusa Palace Hotel

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

4.0 star property
Syracuse
7.2 out of 10, Good, (32)
"Great upgrade Wonderful place "
United States
Veronique
$103 nightly
The price is $117
Dec 12 - Dec 13
Total with taxes and fees
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Hotel Centrale

4.0 star property
Syracuse
7.2 out of 10, Good, (92)
"Close to station and Ortigia -clean and helpful - great staging post."
United Kingdom
Philippa
$104 nightly
The price is $119
Dec 12 - Dec 13
Total with taxes and fees
Hotel Centrale

Borgo Pantano

4.0 star property
Syracuse
9.8 out of 10, Exceptional, (276)
"Beautiful property and excellent breakfast. Lived our stay! "
United States
Feldman
Borgo Pantano

VOI Arenella Resort

4.0 star property
Syracuse
8.0 out of 10, Very Good, (130)
"Loved area"
United States
Frank
VOI Arenella Resort

Villa Fanusa

4.0 star property
Syracuse
8.4 out of 10, Very Good, (44)
"The hotel is located in the countryside so is a bit remote. There are buses but having a car is better. We visited out of high season and had the pool to ourselves every day. We loved that."
United Kingdom
J
Villa Fanusa

Il Podere Hotel Restaurant

4.0 star property
Syracuse
8.4 out of 10, Very Good, (118)
"Staff was very friendly and kind. The rooms are large with enough space for our lugage. We had our own terrasse. The pool was great. "
United States
Tania
Il Podere Hotel Restaurant

Life Hotels Kalaonda Resort

4.0 star property
Syracuse
8.6 out of 10, Excellent, (109)
"Lovely place!"
Canada
Hyun Jin
Life Hotels Kalaonda Resort
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Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

Top Syracuse Hotel Reviews

Price trends for properties with 4 Stars in Syracuse

Less expensive
More expensive
This month
Next month
February
May
$122
$141
Month
Price
January
$141
February
$94
March
$134
April
$151
May
$200
June
$192
July
$175
August
$184
September
$174
October
$149
November
$129
December
$122
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 4 stars in Syracuse. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about Syracuse

The outset of any holiday gets started with picking a location. Syracuse is a popular option with tourists because of everything it offers. Location is everything, but that accounts for more than the area you are flying into. Now that you have got a feeling for this city, it's time you to get to know your residence for the next several days.

Properties as Scenic as the City

Syracuse saw its fair share of visitors in the last year. Expedia's review section features tips and tricks on which accommodation will satisfy your desires for a wonderful vacation. The resorts found here aim to make your stay as gratifying as your days and nights hanging out in Syracuse. These hotels aim to make the grounds and facilities welcoming during your stay. You won't have to search long for to keep up with your exercise schedule, an invigorating spa treatment, or nice dinner.

Rooms have been designed to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, designer bathroom products, and in-room coffee or tea. So, lay back and relax. Moreover, if you find that you're need of anything further, you can rest assured the staff will do their best to ensure you remain satisfied during your time. These properties are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Syracuse Today!

A holiday to Syracuse should be one where you won't have to concern yourself about the little things. With Expedia, you can get great deals on world-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Syracuse?
Look forward to 4-star hotel comfort at Algila Ortigia Charme Hotel. Rated highly by many of our guests, it comes with concierge services and room service. Also take a look at Hotel Roma. Premium bedding and concierge services help make this retreat another popular pick in Syracuse.
How much does it cost to stay in a 4-star hotel in Syracuse?
With Expedia's sort and search filters, locking in a superb deal on a 4-star hotel in Syracuse just got simpler. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and pick the option that best suits your budget and style.

  • Search for the lowest price from $149

What's the difference between 5-star and 4-star hotels in Syracuse?
Offering an inviting traveler experience and upscale décor, 4-star hotels are a fabulous option for your Syracuse vacation. These kinds of accommodations generally come with lots of handy amenities that make it simple to kick back and relax — think complimentary bathrobes, gyms and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically featured at these plush retreats.

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