Find 5 Star Hotels in Central United States from $111

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Central United States 5 Star Hotels

Next weekend
In two weeks

Compare Central United States 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Roosevelt New Orleans, A Waldorf Astoria Hotel

5.0 star property
New Orleans Central Business District
9.2 out of 10, Wonderful, (1003)
"We found our stay here to be very enjoyable."
United States
Lesley
$161 nightly
The price is $190
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Roosevelt New Orleans, A Waldorf Astoria Hotel

Four Seasons Hotel Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (999)
"Amazing hotel"
United States
David
$420 nightly
The price is $493
Dec 28 - Dec 29
Total with taxes and fees
Four Seasons Hotel Chicago

The Langham, Chicago

5.0 star property
Downtown Chicago
9.8 out of 10, Exceptional, (1001)
"Langham is always a superior stay"
United States
THADDEUS LAMONT
$413 nightly
The price is $485
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Langham, Chicago

The Peninsula Chicago

5.0 star property
Downtown Chicago
9.8 out of 10, Exceptional, (1000)
"Excellent service throughout the hotel"
United States
Karen
$475 nightly
The price is $558
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Peninsula Chicago

The Windsor Court

5.0 star property
New Orleans Central Business District
9.8 out of 10, Exceptional, (1002)
"Wonderful stay with my family. Great staff and very clean."
United States
Jonathan
$365 nightly
The price is $428
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Windsor Court

Trump International Hotel & Tower Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (1785)
"Great stay "
United States
Mohammed
$296 nightly
The price is $348
Jan 4 - Jan 5, 2026
Total with taxes and fees
Trump International Hotel & Tower Chicago

Thompson Dallas, by Hyatt

5.0 star property
Downtown Dallas
9.0 out of 10, Wonderful, (479)
"The staff does a truly exceptional job at ensuring their guests are happy. I highly recommend! They always go above and beyond. "
United States
JEFF
$296 nightly
The price is $347
Dec 28 - Dec 29
Total with taxes and fees
Thompson Dallas, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

5.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (912)
"Outstanding hotel "
United States
Hicham
$208 nightly
The price is $246
Dec 14 - Dec 15
Total with taxes and fees
Thompson San Antonio - Riverwalk, by Hyatt

The Post Oak Hotel at Uptown Houston

5.0 star property
The Galleria
9.6 out of 10, Exceptional, (881)
"Beautiful hotel "
United States
nabintou
$485 nightly
The price is $568
Dec 21 - Dec 22
Total with taxes and fees
The Post Oak Hotel at Uptown Houston

Hotel Crescent Court

5.0 star property
Uptown
9.2 out of 10, Wonderful, (1000)
"Quiet, beautiful, and well appointed rooms. "
United States
Jill
$339 nightly
The price is $396
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hotel Crescent Court

The Joseph, a Luxury Collection Hotel, Nashville

5.0 star property
Downtown Nashville
9.4 out of 10, Exceptional, (444)
"The room was spotless and our stay was 5 star service, food, room, and experience. We look forward to a longer stay the next time we visit Nashville!"
United States
Regina
$266 nightly
The price is $313
Dec 22 - Dec 23
Total with taxes and fees
The Joseph, a Luxury Collection Hotel, Nashville

Conrad Nashville

5.0 star property
Downtown Nashville
9.6 out of 10, Exceptional, (1065)
"good hotel and location"
United States
James
$251 nightly
The price is $295
Dec 28 - Dec 29
Total with taxes and fees
Conrad Nashville

Waldorf Astoria Chicago

5.0 star property
Downtown Chicago
9.4 out of 10, Exceptional, (1003)
"Absolutely fantastic hotel great service, you couldn’t ask for more."
United States
J Michael
$396 nightly
The price is $465
Dec 14 - Dec 15
Total with taxes and fees
Waldorf Astoria Chicago

The Joule

5.0 star property
Downtown Dallas
9.2 out of 10, Wonderful, (1004)
"Everything from the entrance, to check in, to check out, was absolutely perfect! "
United States
James
$344 nightly
The price is $404
Dec 22 - Dec 23
Total with taxes and fees
The Joule

Rosewood Mansion on Turtle Creek

5.0 star property
Oak Lawn
9.4 out of 10, Exceptional, (774)
"Excellent facilities, rooms, and food/drink."
United States
Stephen
$722 nightly
The price is $847
Jan 4 - Jan 5, 2026
Total with taxes and fees
Rosewood Mansion on Turtle Creek

1 Hotel Nashville

5.0 star property
Downtown Nashville
9.4 out of 10, Exceptional, (950)
"Our stay at 1 hotel one was a great experience"
United States
Marcela
$266 nightly
The price is $313
Dec 28 - Dec 29
Total with taxes and fees
1 Hotel Nashville

Park Hyatt Chicago

5.0 star property
Downtown Chicago
9.6 out of 10, Exceptional, (1000)
"Stay was amazing!!! The staff was so friendly, kind, and thoughtful! The rooms were soooo beyond perfect and lovely! And the food at the restaurant was amazing.. especially breakfast! You won’t regret staying here!!! "
United States
Larissa
$435 nightly
The price is $511
Jan 2 - Jan 3, 2026
Total with taxes and fees
Park Hyatt Chicago

Four Seasons Hotel New Orleans

5.0 star property
New Orleans Central Business District
9.6 out of 10, Exceptional, (593)
"Great service, early check-in, birthday and holiday amenity was nice touch. "
United States
Matthew
$400 nightly
The price is $469
Dec 18 - Dec 19
Total with taxes and fees
Four Seasons Hotel New Orleans

JW Marriott Nashville

5.0 star property
Downtown Nashville
9.2 out of 10, Wonderful, (1001)
"Fantastic hotel. Great location and service Definitely recommend and will be back "
United States
Phillip
$276 nightly
The price is $325
Dec 22 - Dec 23
Total with taxes and fees
JW Marriott Nashville

The Loren Hotel Austin

5.0 star property
Zilker
9.4 out of 10, Exceptional, (341)
"High quality amenities, great service at Nido, beautiful property."
United States
Ebony
$313 nightly
The price is $366
Dec 14 - Dec 15
Total with taxes and fees
The Loren Hotel Austin
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central United States.
Still don't see what you're looking for?
See all properties in Central United States.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Central United States

During your stay in Central United States, you can discover things to see and do in the local area.

Downtown Nashville which includes a city, a sunset and boating

Top Central United States Hotel Reviews

Find out more about Central United States

Central United States Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Central United States are your dreams come true. From sprawling resorts to fancy hot spots, theseCentral United States 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Central United States, United States of America, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Central United States five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Central United States 5 star hotels.

Frequently asked questions

What are the best 5-star hotels in Central United States?
The Knickerbocker Hotel is a top pick for Expedia customers. The Chatwal, In The Unbound Collection By Hyatt and InterContinental New York Times Square, an IHG Hotel also get glowing reviews from travelers. All located in New York, Central United States, these 5-star hotels will treat you to the luxury experience from the moment you enter the lobby.
How much does it cost to stay in a 5-star hotel in Central United States?
How much you pay for a 5-star hotel in Central United States depends on things such as when you plan to travel and the length of your break. An insider tip for bagging the best deal? Use our pricing filters to check out all of the available hotels for your chosen dates.

  • Search for the lowest price per night from $111

What makes a hotel 5 stars in Central United States?
In Central United States, a hotel must provide a certain level of upscale amenities to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their outstanding service. You'll enjoy things like concierge services, in-room massages and nightly turn-down services. Some may even offer extra touches such as a welcome gift.