Find 5 Star Hotels in Santa Marta from $141

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Marta 5 Star Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Compare Santa Marta 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sauna, steam room, Turkish bath, body treatments, aromatherapy
The Westin Excelsior, Rome

The Westin Excelsior, Rome

5.0 star property
Rome City Centre
8.2 out of 10, Very Good, (744)
"Spacious rooms!!!"
United States
Milana
$362 nightly
The price is $421
Jan 7 - Jan 8, 2026
Total with taxes and fees
The Westin Excelsior, Rome
Exterior
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1006)
"The hotel was the best location to be at. Amazing stay and so convenient."
United States
Jalin
$242 nightly
The price is $290
Jan 5 - Jan 6, 2026
Total with taxes and fees
NH Collection Roma Palazzo Cinquecento
Sports facility
Rome Cavalieri, A Waldorf Astoria Hotel

Rome Cavalieri, A Waldorf Astoria Hotel

5.0 star property
Trionfale
9.2 out of 10, Wonderful, (1004)
"I loved this place, the food and the staff!!"
United States
Arenthia
$342 nightly
The price is $399
Jan 7 - Jan 8, 2026
Total with taxes and fees
Rome Cavalieri, A Waldorf Astoria Hotel
Restaurant
Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese

5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (968)
"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "
Sweden
Daniel
$314 nightly
The price is $369
Dec 15 - Dec 16
Total with taxes and fees
Sofitel Rome Villa Borghese
2 restaurants, Italian cuisine
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1000)
"Excelente hotel "
Mexico
Miguel
$633 nightly
The price is $719
Dec 15 - Dec 16
Total with taxes and fees
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Exterior
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (155)
"Great Staff Great Location"
Canada
cristina
$508 nightly
The price is $582
Dec 15 - Dec 16
Total with taxes and fees
InterContinental Rome Ambasciatori Palace by IHG
Property amenity
W Rome

W Rome

5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (204)
"Amazing hotel, wonderful staff, convenience "
Canada
Anna
$423 nightly
The price is $489
Dec 15 - Dec 16
Total with taxes and fees
W Rome
Exterior
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (499)
"Excellent hotel with great sraff"
United Kingdom
Gary
$545 nightly
The price is $622
Jan 7 - Jan 8, 2026
Total with taxes and fees
Baglioni Hotel Regina - The Leading Hotels of the World
2 bars/lounges
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (145)
"Clean, good breakfast, walkable to major historical ruins"
Canada
Pam
$270 nightly
The price is $320
Jan 7 - Jan 8, 2026
Total with taxes and fees
Radisson Collection Hotel, Roma Antica
Restaurant
Six Senses Rome

Six Senses Rome

5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (58)
"Amazing staff, beautifully decorated hotel, super amenities. Truly wonderful find in the heart of Rome."
United States
Sergio Alfonso
$1,090 nightly
The price is $1,222
Dec 14 - Dec 15
Total with taxes and fees
Six Senses Rome
Garden
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
$524 nightly
The price is $600
Dec 14 - Dec 15
Total with taxes and fees
Villa Agrippina Gran Meliá - The Leading Hotels of the World
View from property
Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection

5.0 star property
Rome City Centre
8.2 out of 10, Very Good, (542)
"Amazing staff service and beautiful room "
United States
Samantha
$355 nightly
The price is $413
Dec 15 - Dec 16
Total with taxes and fees
Sina Bernini Bristol, Autograph Collection
Property entrance
Grand Hotel Palace

Grand Hotel Palace

5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1000)
"Great hotel. Staff is very helpful and professional. "
Canada
anne
$224 nightly
The price is $270
Jan 7 - Jan 8, 2026
Total with taxes and fees
Grand Hotel Palace
View from property
Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World

5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (636)
"The rooftop restaurant for breakfast was amazing.. eat and enjoy the view of the coliseum, and archeological dig… Amazing food selection "
United States
Leslie
$415 nightly
The price is $480
Dec 9 - Dec 10
Total with taxes and fees
Palazzo Manfredi – Small Luxury Hotels of the World
Terrace/patio
Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux

5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1000)
"The staff, room, and amenities were all excellent."
United States
Jason
$252 nightly
The price is $300
Dec 11 - Dec 12
Total with taxes and fees
Hotel Raphaël – Relais & Châteaux
Terrace/patio
Hotel Locarno

Hotel Locarno

5.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (518)
"The staff were very helpful and the hotel is in a great location. "
Canada
Roxanne
$466 nightly
The price is $536
Dec 15 - Dec 16
Total with taxes and fees
Hotel Locarno
Property amenity
Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton

5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (463)
"Stunning property! "
United States
Kaitlin
$360 nightly
The price is $419
Jan 5 - Jan 6, 2026
Total with taxes and fees
Aleph Rome Hotel Curio Collection by Hilton
Restaurant
Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World

5.0 star property
Rome City Centre
10.0 out of 10, Exceptional, (106)
"Great location, beautiful property, very well run and managed. "
United Kingdom
John
$429 nightly
The price is $495
Dec 14 - Dec 15
Total with taxes and fees
Palazzo Roma - The Leading Hotels of the World
Banquet hall
Hassler Roma

Hassler Roma

5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (154)
"We travel a lot one of the best hotels we’ve ever stayed in"
United States
Joel
$1,418 nightly
The price is $1,583
Dec 19 - Dec 20
Total with taxes and fees
Hassler Roma
Suite | Egyptian cotton sheets, premium bedding, down comforters
Palazzo Montemartini Rome, A Radisson Collection Hotel

Palazzo Montemartini Rome, A Radisson Collection Hotel

5.0 star property
Rome City Centre
8.8 out of 10, Excellent, (712)
"Room was amazing and the service was top notch. Staff was attentive and friendly. Lorenzo was an exceptional staff. He remembered us during our stay and constantly checked in on us when he was on shift. "
Singapore
Alvin
$233 nightly
The price is $279
Jan 5 - Jan 6, 2026
Total with taxes and fees
Palazzo Montemartini Rome, A Radisson Collection Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Marta.
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

Via Cavour 15 Rome RM
$198 nightly
The price is $236 total per night from Dec 8 to Dec 9
$236 total
Dec 8 - Dec 9
Total with taxes and fees
8.6/10 Excellent! (1,004 reviews)
Still don't see what you're looking for?
See all properties in Santa Marta.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Marta Hotel Reviews

Find out more about Santa Marta

Santa Marta Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Santa Marta are your dreams come true. From sprawling resorts to fancy hot spots, theseSanta Marta 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Santa Marta, Castelnuovo di Porto, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Santa Marta five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Santa Marta 5 star hotels.

Explore a world of travel with Expedia