Find hotels in Downtown South San Francisco

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Our top choices for Downtown South San Francisco hotels

Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2007)
"Breakfast is great. Staff is great."
United States
Trina
$112 nightly
The price is $131
Dec 20 - Dec 21
Total with taxes and fees
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Interior detail
Airport Inn

Airport Inn

2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (972)
"Very clean room, friendly staff and secure parking."
United States
Christopher
$97 nightly
The price is $114
Jan 7 - Jan 8, 2026
Total with taxes and fees
Airport Inn
Lobby
Inn By The SFO

Inn By The SFO

2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
United States
David
$89 nightly
The price is $105
Jan 3 - Jan 4, 2026
Total with taxes and fees
Inn By The SFO
Fridge, microwave, coffee/tea maker, dining tables
Miller Apartments

Miller Apartments

2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
$125 nightly
The price is $146
Dec 11 - Dec 12
Total with taxes and fees
Miller Apartments
Free daily buffet breakfast
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
10.3 mi from Downtown South San Francisco
9.2 out of 10, Wonderful, (2218)
"This was an ok hotel. Good location. "
Australia
Shannon
$129 nightly
The price is $152
Dec 17 - Dec 18
Total with taxes and fees
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 star property
9.2 mi from Downtown South San Francisco
9.0 out of 10, Wonderful, (4943)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
$119 nightly
The price is $140
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Golden Gateway by IHG
Restaurant
Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica

2.5 star property
5.5 mi from Downtown South San Francisco
8.2 out of 10, Very Good, (1007)
"Beautiful location"
United States
Elena
$129 nightly
The price is $151
Jan 4 - Jan 5, 2026
Total with taxes and fees
Inn at Rockaway San Francisco Pacifica
Premium bedding, down comforters, in-room safe, desk
Harbor View Inn

Harbor View Inn

2.0 star property
11 mi from Downtown South San Francisco
9.2 out of 10, Wonderful, (616)
"very clean, very friendly, close to fun areas"
United States
michael
$126 nightly
The price is $148
Dec 10 - Dec 11
Total with taxes and fees
Harbor View Inn
Terrace/patio
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
10.3 mi from Downtown South San Francisco
8.6 out of 10, Excellent, (1471)
"Clean and great location "
United States
Shawn
$153 nightly
The price is $180
Dec 14 - Dec 15
Total with taxes and fees
Hyatt Centric Fisherman's Wharf San Francisco
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
10.4 mi from Downtown South San Francisco
9.0 out of 10, Wonderful, (7189)
"Great staff, clean rooms, good breakfast buffet"
United States
Debra
$164 nightly
The price is $193
Dec 18 - Dec 19
Total with taxes and fees
Hotel Riu Plaza Fisherman's Wharf
Exterior
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4.0 star property
15.7 mi from Downtown South San Francisco
8.2 out of 10, Very Good, (3914)
"Great place to stay!"
United States
Rafael
$119 nightly
The price is $137
Dec 16 - Dec 17
Total with taxes and fees
DoubleTree by Hilton Hotel Berkeley Marina
Reception
Mayflower Hotel

Mayflower Hotel

2.0 star property
9.2 mi from Downtown South San Francisco
8.8 out of 10, Excellent, (199)
"Great hotel, would stay again. "
United States
Bernadette
$92 nightly
The price is $109
Jan 7 - Jan 8, 2026
Total with taxes and fees
Mayflower Hotel
Front of property
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2.0 star property
9.1 mi from Downtown South San Francisco
8.6 out of 10, Excellent, (1098)
"Excellent location, excellence staff"
United States
james
$67 nightly
The price is $79
Dec 16 - Dec 17
Total with taxes and fees
FOUND Hotel Carlton, Nob Hill
Front of property - evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4.0 star property
9.6 mi from Downtown South San Francisco
8.6 out of 10, Excellent, (2105)
"Great stay "
United States
Samantha
$93 nightly
The price is $110
Dec 21 - Dec 22
Total with taxes and fees
Hilton San Francisco Financial District
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

3.0 star property
15.5 mi from Downtown South San Francisco
9.0 out of 10, Wonderful, (1076)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
$134 nightly
The price is $158
Jan 8 - Jan 9, 2026
Total with taxes and fees
Half Moon Bay Lodge
Exterior
Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North

3.0 star property
The East Side, 1 mi from Downtown South San Francisco
8.4 out of 10, Very Good, (1009)
"Staff, amenities, clean rooms "
United States
ROMEO JR
$91 nightly
The price is $107
Dec 20 - Dec 21
Total with taxes and fees
Hilton Garden Inn San Francisco Arpt North
Front of property
Hotel Majestic

Hotel Majestic

3.5 star property
9 mi from Downtown South San Francisco
9.2 out of 10, Wonderful, (1016)
"Friendly front desk and staff."
United States
Joanne
$128 nightly
The price is $149
Dec 15 - Dec 16
Total with taxes and fees
Hotel Majestic
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4.0 star property
10.4 mi from Downtown South San Francisco
9.0 out of 10, Wonderful, (3832)
"We stay here a lot, great place and safe."
United States
Albert
$168 nightly
The price is $198
Dec 14 - Dec 15
Total with taxes and fees
Hotel Caza Fisherman's Wharf
In-room safe, desk, laptop workspace, iron/ironing board
Star Motel

Star Motel

2.0 star property
9.9 mi from Downtown South San Francisco
9.4 out of 10, Exceptional, (293)
"Nice room and great location! "
United States
Teryn
$74 nightly
The price is $87
Dec 14 - Dec 15
Total with taxes and fees
Star Motel
Front of property - evening/night
Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 star property
8.9 mi from Downtown South San Francisco
9.4 out of 10, Exceptional, (2636)
"The entire hotel was fabulous!"
United States
Nicole
$191 nightly
The price is $225
Dec 14 - Dec 15
Total with taxes and fees
Hotel Nikko San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Union Square which includes a high rise building and a city

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco featuring railway items

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman\'s Wharf featuring a bay or harbor

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market featuring skyline, a city and city views

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent
"Staff was courteous "
Nicole 4-night trip
Posted 19 hours ago
DoubleTree by Hilton Hotel Berkeley Marina

Frequently asked questions

What are the best hotels in Downtown South San Francisco that travelers recommend?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is a great choice for travelers, receiving an excellent review score of 8.0. This hotel welcomes guests with a variety of amenities designed for comfort and convenience. Families will appreciate the spacious rooms that include cribs at no extra charge, making it easier for parents traveling with young children. The outdoor pool is superb for a refreshing dip after a day of exploring, and the hotel's pet-friendly policy means you can bring your furry friends along for the adventure.
What are the best family hotels in Downtown South San Francisco?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is a fantastic family-friendly option for those visiting Downtown South San Francisco. Rated 8.0 by travelers, this hotel boasts key amenities that cater to families, including spacious rooms equipped with a sofa bed and free cribs for the little ones. Guests appreciate the convenience of having a pool, great for unwinding after a day of adventure.

Another great choice is Inn By The SFO, where families can enjoy a friendly setting with a customer review rating of 7.8. This hotel offers free accommodations for children, along with cribs and rollaway beds to ensure every family member has a comfortable stay. With daily housekeeping and in-room microwaves, parents will find the convenience they desire while traveling with children.
What hotels in Downtown South San Francisco offer free breakfast?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is a family-friendly hotel that stands out in Downtown South San Francisco, boasting an excellent guest review score of 8.0. Guests appreciate the convenience of complimentary breakfasts, available daily, which is especially welcoming for families looking to start their day off right without extra costs.
What are the best budget hotels in Downtown South San Francisco?
If you're looking for budget-friendly accommodations in Downtown South San Francisco, the La Quinta Inn & Suites by Wyndham San Francisco Airport N is a fantastic option. With a traveler review rating of 8.0, this hotel not only provides complimentary breakfast on weekends but also features an outdoor pool—a superb way for families to unwind after a day of exploring. Guests appreciate the added convenience of free airport transportation, making it a stress-free choice for those traveling with children.

Another solid option is the Airport Inn, which boasts an excellent review score of 8.6. This property offers free self-parking and Wi-Fi in the rooms, making it easy for families to stay connected and keep their travel costs down. The accessible parking and a lovely terrace provide extra convenience for guests.

For families, both properties offer cribs at no additional charge, ensuring a comfortable stay for your little ones.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Downtown South San Francisco.
How can I save on a Downtown South San Francisco hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Downtown South San Francisco hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Downtown South San Francisco hotel?
Hotel prices in Downtown South San Francisco often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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