Find Business Hotels in Clayton, NC

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Clayton Business Hotels

Our top choices for Clayton business-friendly hotels

Interior entrance
Magnolia Inn

Magnolia Inn

2.0 star property
Clayton
9.4 out of 10, Exceptional, (6)
"The room was clean and very nicely appointed. The breakfast was fabulous. Location was also great with easy walking distance to restaurants. "
United States
Helen
$222 nightly
The price is $249
Dec 16 - Dec 17
Total with taxes and fees
Magnolia Inn
Rooftop terrace
Hyatt House Raleigh Downtown/Seaboard Station

Hyatt House Raleigh Downtown/Seaboard Station

3.5 star property
Downtown Raleigh
9.4 out of 10, Exceptional, (640)
"Staff were very friendly "
United States
Henry
$131 nightly
The price is $149
Dec 15 - Dec 16
Total with taxes and fees
Hyatt House Raleigh Downtown/Seaboard Station
Standard two queens | In-room safe, desk, blackout drapes, iron/ironing board
Hampton Inn by Hilton Dunn

Hampton Inn by Hilton Dunn

2.5 star property
Dunn
8.4 out of 10, Very Good, (1001)
"Great place to stay "
United States
Jon
$79 nightly
The price is $89
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn by Hilton Dunn
Standard Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Comfort Inn & Suites Fuquay Varina

Comfort Inn & Suites Fuquay Varina

2.5 star property
Fuquay-Varina
8.0 out of 10, Very Good, (659)
"The staff were very friendly and made sure we had everything we needed. "
United States
Terry
$85 nightly
The price is $96
Jan 4 - Jan 5, 2026
Total with taxes and fees
Comfort Inn & Suites Fuquay Varina
Lobby
Sleep Inn & Suites Smithfield near I-95

Sleep Inn & Suites Smithfield near I-95

2.5 star property
Smithfield
9.4 out of 10, Exceptional, (1001)
"Nice place to stay-comfortable beds ! Good breakfast."
United States
Paula
$76 nightly
The price is $85
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sleep Inn & Suites Smithfield near I-95
Free continental breakfast
Quality Inn Selma - Smithfield

Quality Inn Selma - Smithfield

2.5 star property
Selma
8.0 out of 10, Very Good, (1000)
"Good staff. "
United States
Jesus
$64 nightly
The price is $71
Dec 18 - Dec 19
Total with taxes and fees
Quality Inn Selma - Smithfield
Full-size fridge, microwave, stovetop
My Place Hotel Raleigh Garner NC

My Place Hotel Raleigh Garner NC

2.0 star property
Garner
9.2 out of 10, Wonderful, (104)
"Very nice hotel…so glad I found this place!"
United States
Rashon
$89 nightly
The price is $98
Dec 15 - Dec 16
Total with taxes and fees
My Place Hotel Raleigh Garner NC
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board
La Quinta Inn & Suites by Wyndham Selma/Smithfield I-95

La Quinta Inn & Suites by Wyndham Selma/Smithfield I-95

3.0 star property
Selma
7.8 out of 10, Good, (1000)
"Clean room, friendly staff, quick check in"
United States
Robert
$80 nightly
The price is $89
Jan 1 - Jan 2, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Selma/Smithfield I-95
Free daily buffet breakfast
Country Inn & Suites by Radisson, Smithfield-Selma, NC

Country Inn & Suites by Radisson, Smithfield-Selma, NC

3.0 star property
Smithfield
7.4 out of 10, Good, (1000)
"very nice i will stay again"
United States
Donna
$93 nightly
The price is $104
Dec 16 - Dec 17
Total with taxes and fees
Country Inn & Suites by Radisson, Smithfield-Selma, NC
Free buffet breakfast
Holiday Inn Express Apex - Raleigh by IHG

Holiday Inn Express Apex - Raleigh by IHG

2.5 star property
Apex
9.2 out of 10, Wonderful, (599)
"Staff was very friendly and room was clean! "
United States
Kassidy
$86 nightly
The price is $97
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Apex - Raleigh by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Clayton Hotel Reviews

La Quinta Inn & Suites by Wyndham Raleigh Downtown North

La Quinta Inn & Suites by Wyndham Raleigh Downtown North

10/10 Excellent
"Comfy and clean stay for a family of four. Consistently great service."
Chidi 3-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Raleigh Downtown North

Frequently asked questions

How much do business-friendly hotels in Clayton cost?
Rates for business hotels in Clayton range between $71 and $249 per night. Whatever your budget, Expedia will help you locate the best space to get the job done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Clayton?
Clayton has multiple business-friendly hotels with a total average guest review rating of 8.5. One of the most popular is Holiday Inn Express Clayton, an IHG Hotel. Put your laptop bag down and relax at this 2.5-stars option, which includes a swimming pool and hypo-allergenic bedding. Another sought-after stay among corporate travelers is Hampton Inn Raleigh/Clayton I-40. It has a 2.5-stars rating and amenities such as pool sun loungers and a swimming pool.
How many business-friendly hotels are there in Clayton?
When work takes you to Clayton, there are 1 business-friendly hotels to choose from. These properties combine a suitable location with the conveniences corporate travelers need.
What are the best cheap business-friendly hotels in Clayton?
Save more on your work trip to Clayton by booking one of our business-friendly hotels that start from only $71 per night. One low-priced property is Holiday Inn Express Clayton, an IHG Hotel, which comes with handy amenities like hypo-allergenic bedding and a swimming pool. Hampton Inn Raleigh/Clayton I-40 is another leading pick for corporate travelers with a strict budget. It features a swimming pool and pool sun loungers. If you're searching for something fun and free to do in between meetings and conferences in Clayton, Clemmons Educational State Forest is worth adding to your list. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Clayton?
Super 8 by Wyndham Garner/Clayton/Raleigh mixes work and play. Pillow top mattresses and a swimming pool are among the many conveniences at this business-friendly property, located around 7 miles southwest of downtown Clayton.There are lots of things to see and do in Clayton. Take time out from your business schedule to visit cool attractions like Riverwood Golf Club and Clemmons Educational State Forest.
Are there any family-friendly hotels in Clayton that are also business friendly?
Comfort Inn Garner Clayton I-40 is a popular choice for family and corporate travelers. Complimentary breakfast and laundry facilities are the start of the amenities at this 2.5-stars Clayton getaway. Once you've gotten work out of the way, there's no shortage of family-friendly attractions to visit around Clayton. Riverwood Golf Club and Clemmons Educational State Forest are two popular options.
Why book your business-friendly hotel in Clayton with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when work takes you on the road. From conference spaces and room service to on-site cafés and restaurants, our accommodations have the things you'll need to get the job done.
How can I find cheap business-friendly hotels in Clayton?
Click on the "business friendly" filter, located just under the "traveler experience" heading, to find cheap business-friendly hotels in Clayton. Then narrow your search by your preferred hotel star rating and budget. Choosing a stay outside the city center can also help you save.
What is there to do in Clayton near my business-friendly hotel?
If you'd like to explore the sights of Clayton, find your way to Riverwood Golf Club. It's a favorite with locals and tourists alike.

Explore a world of travel with Expedia