Search Hotels in Pemiscot County

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Compare 101 hotels in Pemiscot County with room rates, reviews, and availability. Most hotels are fully refundable.

Front of property
The Farmstead Hotel

The Farmstead Hotel

2.5 star property
Caruthersville
8.8 out of 10, Excellent, (460)
"Clean rooms and really comfortable beds!"
United States
Andrea
$80 nightly
The price is $92
Dec 15 - Dec 16
Total with taxes and fees
The Farmstead Hotel
Lobby
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3.0 star property
Hayti
9.4 out of 10, Exceptional, (1001)
"Staff is very friendly. Breakfast was good. "
United States
Samantha
$94 nightly
The price is $107
Dec 13 - Dec 14
Total with taxes and fees
Drury Inn & Suites Hayti Caruthersville
Standard Double Room, 2 Queen Beds, Transfer Shower | Desk, laptop workspace, free WiFi
Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville

2.0 star property
Caruthersville
8.6 out of 10, Excellent, (103)
"Room was clean staff was really nice"
United States
Toni
$116 nightly
The price is $132
Dec 19 - Dec 20
Total with taxes and fees
Century Casino & Hotel Caruthersville
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 star property
Portageville
8.0 out of 10, Very Good, (724)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
$59 nightly
The price is $64
Dec 14 - Dec 15
Total with taxes and fees
New Orleans Inn Portageville
Standard Double Room, 2 Double Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets
Quality Inn Hayti North

Quality Inn Hayti North

2.5 star property
Hayti
6.8 out of 10, (468)
"Staff was good "
United States
Gabriel
$59 nightly
The price is $67
Jan 7 - Jan 8, 2026
Total with taxes and fees
Quality Inn Hayti North
Living area
House on the hill, with an amazing downtown street view!

House on the hill, with an amazing downtown street view!

Caruthersville
House on the hill, with an amazing downtown street view!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pemiscot County Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Staff is very friendly. Breakfast was good. "
Samantha 1-night trip
Posted 3 days ago
Drury Inn & Suites Hayti Caruthersville

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