Title: Mesilla Vacation Rentals from $133: Search Short-Term Rentals | Expedia.com

[Mesilla Travel Guide](https://expedia.com/Mesilla.dx132684)[Hotels in Mesilla](https://expedia.com/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Flights to Mesilla](https://expedia.com/Cheap-Flights-To-Mesilla.d132684.Travel-Guide-Flights)[Car Rentals in Mesilla](https://expedia.com/Car-Rentals-In-Mesilla.d132684.Car-Rental-Guide)[Mesilla Vacation Packages](https://expedia.com/Mesilla.d132684.Destination-Travel-Guides)

![Red chile doorway Mesilla NM](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 31 - Aug 2](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-07-31&endDate=2026-08-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Mesilla vacation rentals

![Property grounds](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/71d7ce53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace, DVD player, stereo](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/7ff2efb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/6c9ad3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/cbe8afa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

[](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information)

Mesilla

10/10

Exceptional

(82 reviews)

"Very cozy and walking distance to shops and restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miriam P.

$201 nightly

$226 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/f396e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/935f6d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/5e2c2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/c70868a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Southwest Gem just minutes from White Sands National Park

[](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information)

Las Cruces

10/10

Exceptional

(28 reviews)

"kitchen fully equipped, pet friendly"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

$253 nightly

$269 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/b11f6a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/636569e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/d91a3a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/78146abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tuscan Villa Outdoor Living, Jacuzzi & Gym

[](https://www.expedia.com/Las-Cruces-Hotels-Tuscan-Villa-Outdoor-Living.h93674654.Hotel-Information)

Las Cruces

9.4/10

Exceptional

(18 reviews)

"Beautiful house and would stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alethea S.

$259 nightly

$281 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Tuscan-Villa-Outdoor-Living.h93674654.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/56b96b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/9419cf92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/e1387651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/fbac0868.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2 bedroom retreat at the end of the street equipped for any length stay

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information)

Las Cruces

10/10

Exceptional

(4 reviews)

"Very clean with a very responsive host."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wallace A.

$172 nightly

$196 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/0606d2be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/fa527983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/c7b17bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/1ecfd1c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 4 Bedroom Contemporary Model Home

[](https://www.expedia.com/Las-Cruces-Hotels-4-Bedroom-Contemporary-Model-Home.h93494538.Hotel-Information)

Las Cruces

9.2/10

Wonderful

(34 reviews)

"Great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Caroline M.

$224 nightly

$243 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-4-Bedroom-Contemporary-Model-Home.h93494538.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/122000000/121180000/121171700/121171630/285bf7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121180000/121171700/121171630/74888916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/122000000/121180000/121171700/121171630/1d774d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/122000000/121180000/121171700/121171630/6a425eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom Casita In Mesilla Park

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Casita-In-Mesilla-Park.h121171630.Hotel-Information)

Las Cruces

10/10

Exceptional

(6 reviews)

"Anyone can have fun in this lovely neighborhood"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thom S.

$145 nightly

$157 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Casita-In-Mesilla-Park.h121171630.Hotel-Information)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/bc0a9d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/1aa64a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/02adc68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/ccb4ff70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Cruces Home w/ Fenced Yard: Recently Remodeled

[](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information)

Las Cruces

10/10

Exceptional

(1 review)

"The host was thoughful. He provided all the information we needed and responded our questions really quickly. The house was clean and very well organized. This house had the best view at night. We will definitely visit again when we go Santa fe. 😊 "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nam

$223 nightly

$256 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/c3e0eeb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/cb3ffc47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Golf](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/cfc6ffff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/8cbc52c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### New Casita/Suite No cleaning fee.

[](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information)

Las Cruces

9.6/10

Exceptional

(31 reviews)

"Comfortable, nice suite; Was a short overnight stay. Would stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susie S.

$123 nightly

$133 total

Apr 9 - Apr 10

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/62bda261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/10009bf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/926efd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/c93aa40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 4098/Lyle SW · Brand New Home in Beautiful Golf Course Community

[](https://www.expedia.com/Las-Cruces-Hotels-4098Lyle-SW-Brand-New-Home-In-Beautiful-Golf-Course-Community.h91653050.Hotel-Information)

Las Cruces

10/10

Exceptional

(14 reviews)

"Nice, new and clean place. Nearby amenities and places to eat. Would book again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveler

$300 nightly

$321 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-4098Lyle-SW-Brand-New-Home-In-Beautiful-Golf-Course-Community.h91653050.Hotel-Information)

![Desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/fc16f9a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/a934bfa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/fb81d0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/61c8b42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio w/queen bed, pets ok, 3 min to Farmer's mkt

[](https://www.expedia.com/Las-Cruces-Hotels-Studio-Wqueen-Bed.h101216445.Hotel-Information)

Las Cruces

10/10

Exceptional

(2 reviews)

"Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert T.

$173 nightly

$194 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Studio-Wqueen-Bed.h101216445.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/bf624d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/a8b4113b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/0a1aede2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/539e32d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information)

Las Cruces

9.4/10

Exceptional

(8 reviews)

"I was truly impressed with my rental. It was extremely clean, quiet, comfortable and pleasant. The price was reasonable and we enjoyed it tremendously! Thank you John and Erica!!! My son enjoyed the popcorn. Hope to be renting this again soon!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert M.

$140 nightly

$152 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/7588e101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/80f58473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/ce945618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/e6e7721e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Family-Friendly 3BR2BA Home with Enclosed Backyard

[](https://www.expedia.com/Las-Cruces-Hotels-Lotus-Blossom.h59194832.Hotel-Information)

Las Cruces

8.8/10

Excellent

(33 reviews)

"nice neighborhood, clean house, quick response from host, will be returning for sure"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alex A.

$248 nightly

$282 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Lotus-Blossom.h59194832.Hotel-Information)

![TV, fireplace](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/4511722c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/9db61b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/6ee2a508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/w1024h1518x0y18-d8b4e67d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stylish & Comfy House with Backyard and Parking

[](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information)

Las Cruces

10/10

Exceptional

(32 reviews)

"Great location and perfect for our needs."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer M.

$308 nightly

$311 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/9fbbfb46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/d57dbe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/42d3fcef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653058/131c50fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy

[](https://www.expedia.com/Las-Cruces-Hotels-4014Russ-Modern-Brand-New-Luxury-Home-With-Community-Pool.h91653058.Hotel-Information)

Las Cruces

9.6/10

Exceptional

(12 reviews)

"We really enjoyed staying here. It was clean, the furnishings were really nice, the location was great and the hosts were excellent. We would stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marc R.

$293 nightly

$314 total

Apr 19 - Apr 20

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-4014Russ-Modern-Brand-New-Luxury-Home-With-Community-Pool.h91653058.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/2e3e8863.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/93854e6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/c1e00df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/52479f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

[](https://www.expedia.com/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information)

Las Cruces

9.0/10

Wonderful

(19 reviews)

"Clean, well furnished and stocked linens and essentials. Pet friendly and large enough for family."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jo Anne C.

$172 nightly

$187 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/d537f667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/490d7bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/9523e9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/47bb0497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yucca House | Views, Jetted Bath, Central Retreat

[](https://www.expedia.com/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information)

Las Cruces

9.8/10

Exceptional

(39 reviews)

"Comfortable, clean, bright accommodations. Well-stocked kitchen. Lovely backyard with beautiful view of Organ Mountains. Perfect for our stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen L.

$278 nightly

$316 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93840000/93834800/93834720/w1080h1059x0y0-3ee29ec6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93840000/93834800/93834720/5446b68e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93840000/93834800/93834720/72221d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/94000000/93840000/93834800/93834720/a151ef50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ritz serene spa sanctuary hot tub, mountain view, patio for the whole family

[](https://www.expedia.com/Las-Cruces-Hotels-The-Ritz-Serene-Spa-Sanctuary-Hot-Tub.h93834720.Hotel-Information)

Las Cruces

9.6/10

Exceptional

(47 reviews)

"Loved the place the house was very beautiful and comfortable would highly choose this place again . "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dee N.

$170 nightly

$184 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-The-Ritz-Serene-Spa-Sanctuary-Hot-Tub.h93834720.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95030000/95026300/95026235/b61520d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95030000/95026300/95026235/bc1240d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/96000000/95030000/95026300/95026235/732eda0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95030000/95026300/95026235/5e99628d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.

[](https://www.expedia.com/Las-Cruces-Hotels-Casa-Del-Sol-Peaceful-Retreat-In-Beautiful-Mesilla.h95026235.Hotel-Information)

Mesilla

9.8/10

Exceptional

(27 reviews)

"Everything was wonderful. Mesilla is charming as is the host. We used this as our base while exploring White Sands National Park and it was perfect. If we find ourselves in this area again we know right where to stay:)"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$158 nightly

$171 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Casa-Del-Sol-Peaceful-Retreat-In-Beautiful-Mesilla.h95026235.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/340987b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/b2e444b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/5293b0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/88000000/87800000/87795900/87795874/fba7f900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Sonoma | Spacious, Central Retreat | Peloton

[](https://www.expedia.com/Las-Cruces-Hotels-NEW-Casa-Sonoma-Spacious.h87795874.Hotel-Information)

Las Cruces

10/10

Exceptional

(48 reviews)

"Beautiful place! Definitely will stay there again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Greg G.

$270 nightly

$307 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-NEW-Casa-Sonoma-Spacious.h87795874.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/bb476c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/4e60082d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/914a9393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/85000000/84260000/84256900/84256832/f87558b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfy SW Home with Private Yard & Mountain Views!

[](https://www.expedia.com/Las-Cruces-Hotels-Comfy-SW-Home-With-Private-Yard-Mountain-Views.h84256832.Hotel-Information)

Las Cruces

10/10

Exceptional

(24 reviews)

"Clean well stocked home, quiet corner of the neighborhood. Nice Stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason B.

$352 nightly

$400 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Las-Cruces-Hotels-Comfy-SW-Home-With-Private-Yard-Mountain-Views.h84256832.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22&regionId=132684&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=COTTAGE)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=CONDO)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=VILLA)

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## Top Mesilla Hotel Reviews

![Days Inn by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/b4a415ed_y.jpg)

### Days Inn by Wyndham Las Cruces

8/10 Good

"Room was clean and comfortable. No coffee in the rooms "

[](https://expedia.com/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain](https://images.trvl-media.com/lodging/1000000/80000/75400/75365/e54f14db_y.jpg)

### La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

8/10 Good

"The room and public areas were clean. The staff were pleasant and helpful. The shower temp and water pressure was wonderful! I could have stayed in it all morning. It is an older building. We had a tile along the baseboard that had come off in the bathroom but they logged it in at the front desk when I reported it. The property is in desperate need of some upgrades. Some of the furniture and all the carpet are really showing heavy use wear."

[](https://expedia.com/Las-Cruces-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Las-Cruces-Organ-Mountain.h75365.Hotel-Information)

![Ramada Hotel & Conference Center by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/10000/3900/3871/1a82ee39_y.jpg)

### Ramada Hotel & Conference Center by Wyndham Las Cruces

6/10 Okay

"Room was clean and the bed wasn't too bad. It is an older hotel, so the A/C was loud when it came on. Shower was elevated and a little hard to get in and out of if you have any physical disabilities. They did have a handrail, but the height would be harder for those of shorter stature. You would basically have to sit down on the edge of the tub and flip around. "

[](https://expedia.com/Las-Cruces-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-Las-Cruces.h3871.Hotel-Information)

![Holiday Inn Express & Suites Las Cruces North by IHG](https://images.trvl-media.com/lodging/5000000/4670000/4663400/4663329/f4f7b494_y.jpg)

### Holiday Inn Express & Suites Las Cruces North by IHG

8/10 Good

"Very clean. Hot tub was cold so that was disappointing "

[](https://expedia.com/Las-Cruces-Hotels-Holiday-Inn-Express-Suites-Las-Cruces-North.h4663329.Hotel-Information)

![Best Western Mission Inn](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/798cead2_y.jpg)

### Best Western Mission Inn

8/10 Good

"Beds confy, quiet area, pets welcome, front desk friendly. Hotel is older need some renovation. But for a one night stay the price was right. We stayed going and on our return trip. "

[](https://expedia.com/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information)

![Comfort Suites Las Cruces I-25 North](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/a92d487e_y.jpg)

### Comfort Suites Las Cruces I-25 North

10/10 Excellent

"The breakfast was fresh although they closed it off at 9am and we missed it the first night. Access to White Sands was perfect."

[](https://expedia.com/Las-Cruces-Hotels-Comfort-Suites-Las-Cruces-I-25-North.h10320201.Hotel-Information)

![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg)

### Comfort Suites University Las Cruces

4/10 Poor

"Parking was good, breakfast was so so Front desk personnel were non helpful and ignorant on problems we encountered. Manager was supposed to contact us on the non availability of HOT water, has not . For the price you guys charge I should have found a better place to stay. "

[](https://expedia.com/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information)

![Drury Inn & Suites Las Cruces](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/46263956_y.jpg)

### Drury Inn & Suites Las Cruces

10/10 Excellent

"Gym and Laundry were not used"

[](https://expedia.com/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information)

![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg)

### Hotel Encanto de Las Cruces

8/10 Good

"Clean, quiet and high class. The only downside was they didnt clean our room the last night"

[](https://expedia.com/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information)

## Find out more about Mesilla

**Everything you need to know about Mesilla vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesilla vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesilla vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Mesilla vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Mesilla. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesilla in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $133 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Mesilla rentals**

At Expedia, we put the best Mesilla vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesilla vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Mesilla ](https://expedia.com/Mesilla-Private-Vacation-Homes.d132684-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Mesilla ](https://expedia.com/Mesilla-Apartments.d132684-aaApartments.Travel-Guide-Accommodation)
- [Cottages in Mesilla ](https://expedia.com/Mesilla-Cottages.d132684-aaCottages.Travel-Guide-Accommodation)
- [Condo Rentals in Mesilla ](https://expedia.com/Mesilla-Condos.d132684-aaCondos.Travel-Guide-Accommodation)
- [Villas in Mesilla ](https://expedia.com/Mesilla-Villas.d132684-aaVillas.Travel-Guide-Accommodation)
- [Guest Houses in Mesilla ](https://expedia.com/Mesilla-Guest-Houses.d132684-aaGuestHouses.Travel-Guide-Accommodation)
- [Motels in Mesilla ](https://expedia.com/Mesilla-Motels.d132684-aaMotels.Travel-Guide-Accommodation)
- [Farmstay in Mesilla ](https://expedia.com/Mesilla-Agritourism.d132684-aaAgritourism.Travel-Guide-Accommodation)

## Frequently asked questions

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### What’s there to see and do in Mesilla?

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Cars

- [Car rentals in Santa Fe](https://expedia.com/Car-Rentals-In-Santa-Fe.d180028.Car-Rental-Guide)
- [Car rentals in Las Cruces](https://expedia.com/Car-Rentals-In-Las-Cruces.d2137.Car-Rental-Guide)

Packages

- [Santa Fe Vacation](https://expedia.com/Santa-Fe.d180028.Destination-Travel-Guides)

General

- [Visit Ruidoso](https://expedia.com/Ruidoso.dx6054982)
- [Where to stay in Santa Fe](https://expedia.com/Santa-Fe.dx180028.Where-To-Stay)