Title: Mesilla Vacation Rentals from $133: Search Short-Term Rentals | Expedia.com [Mesilla Travel Guide](https://expedia.com/Mesilla.dx132684)[Hotels in Mesilla](https://expedia.com/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Flights to Mesilla](https://expedia.com/Cheap-Flights-To-Mesilla.d132684.Travel-Guide-Flights)[Car Rentals in Mesilla](https://expedia.com/Car-Rentals-In-Mesilla.d132684.Car-Rental-Guide)[Mesilla Vacation Packages](https://expedia.com/Mesilla.d132684.Destination-Travel-Guides) ![Red chile doorway Mesilla NM](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesilla vacation rentals ![Property grounds](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/71d7ce53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/a93b2a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/6c9ad3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, stereo](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/7ff2efb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian [](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information) Mesilla 10/10 Exceptional (82 reviews) "Very cozy and walking distance to shops and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miriam P. $199 nightly $224 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information) ![Desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/fc16f9a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/61c8b42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/fb81d0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101220000/101216500/101216445/4a23dd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio w/queen bed, pets ok, 3 min to Farmer's mkt [](https://www.expedia.com/Las-Cruces-Hotels-Studio-Wqueen-Bed.h101216445.Hotel-Information) Las Cruces 10/10 Exceptional (2 reviews) "Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert T. [](https://www.expedia.com/Las-Cruces-Hotels-Studio-Wqueen-Bed.h101216445.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/103000000/102620000/102612000/102611978/w507h683x259y0-eb3a707a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/103000000/102620000/102612000/102611978/w506h683x259y0-2dd98c76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102620000/102612000/102611978/w507h683x259y0-5f21934e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/103000000/102620000/102612000/102611978/w527h683x257y0-b3f6e29e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Elite Casita with EV Level II Charger & Indoor Jet Tub [](https://www.expedia.com/Las-Cruces-Hotels-Elite-Casita.h102611978.Hotel-Information) Las Cruces 10/10 Exceptional (2 reviews) "Great place!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tera W. $235 nightly $255 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Elite-Casita.h102611978.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/bc0a9d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/c60f4206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/ccb4ff70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/583ee9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces Home w/ Fenced Yard: Recently Remodeled [](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) Las Cruces $223 nightly $256 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/4511722c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/w1024h1518x0y18-d8b4e67d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/6ee2a508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/9db61b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish & Comfy House with Backyard and Parking [](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information) Las Cruces 10/10 Exceptional (32 reviews) "Great location and perfect for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer M. $330 nightly $333 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/56b96b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/e1387651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/52566cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/96f09bc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2 bedroom retreat at the end of the street equipped for any length stay [](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information) Las Cruces 10/10 Exceptional (1 review) "Great condition" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela E. $172 nightly $196 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89720000/89715600/89715507/w904h683x59y0-d1a8f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89720000/89715600/89715507/d07522a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89720000/89715600/89715507/060bda53_edited_cc13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89720000/89715600/89715507/w506h683x259y0-cd49fdba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful and comfortable two bedroom apartment [](https://www.expedia.com/Organ-Hotels-Beautiful-And-Comfortable-Two-Bedroom-Apartment.h89715507.Hotel-Information) Las Cruces 10/10 Exceptional (3 reviews) "We loved the location, really easy to get to the university and the shopping areas. Great place for our family to meet and gather! We were very pleased with the location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) tyra R. $234 nightly $250 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Organ-Hotels-Beautiful-And-Comfortable-Two-Bedroom-Apartment.h89715507.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/bf624d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/0a1aede2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/539e32d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/e36b9650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information) Las Cruces 9.8/10 Exceptional (7 reviews) "I was truly impressed with my rental. It was extremely clean, quiet, comfortable and pleasant. The price was reasonable and we enjoyed it tremendously! Thank you John and Erica!!! My son enjoyed the popcorn. Hope to be renting this again soon!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert M. $140 nightly $152 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/574ee83f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/2ecd8012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/3bc41fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653064/9199dd42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pulsar · Brand New Comfortable 4/3.5 Home Near Parks [](https://www.expedia.com/Las-Cruces-Hotels-Pulsar-Brand-New-Comfortable-435-Home-Near-Parks.h91653064.Hotel-Information) Las Cruces 9.8/10 Exceptional (42 reviews) "Nice house with nice plenty of bedrooms and bathrooms. Good for a big family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa B. [](https://www.expedia.com/Las-Cruces-Hotels-Pulsar-Brand-New-Comfortable-435-Home-Near-Parks.h91653064.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/c3e0eeb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/2137413f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/cfc6ffff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/8cbc52c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Casita/Suite No cleaning fee. [](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information) Las Cruces 9.6/10 Exceptional (30 reviews) "Comfortable, nice suite; Was a short overnight stay. Would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susie S. $123 nightly $133 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/f396e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/a357e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/c70868a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/935f6d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southwest Gem just minutes from White Sands National Park [](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information) Las Cruces 10/10 Exceptional (28 reviews) "This was extremely cute house. Had everything we needed to make our trip complete. Also, dog friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly H. $252 nightly $268 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/115000000/114150000/114149200/114149132/99084292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114150000/114149200/114149132/3549e0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/115000000/114150000/114149200/114149132/47eaf511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/115000000/114150000/114149200/114149132/455f38df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gardner Casita - Central Location [](https://www.expedia.com/Las-Cruces-Hotels-Gardner-Casita-Central-Location.h114149132.Hotel-Information) Las Cruces 10/10 Exceptional (8 reviews) "Very nice and very clean. We appreciated the bigger bath towels and nice linens on the beds. It felt like a very safe neighborhood. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer A. $293 nightly $318 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Gardner-Casita-Central-Location.h114149132.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653087/c82baeeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653087/6f0152ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653087/839f65ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653087/c8359b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4010 · Comfortable New Home with community pool and golf [](https://www.expedia.com/Las-Cruces-Hotels-4010-Comfortable-New-Home-With-Community-Pool-And-Golf.h91653087.Hotel-Information) Las Cruces 10/10 Exceptional (3 reviews) "It was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joni S. $322 nightly $345 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-4010-Comfortable-New-Home-With-Community-Pool-And-Golf.h91653087.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653080/84e9ef94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653080/7ef1a14f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, video games](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653080/2e43ab1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653080/b8825859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agua Caliente · Family Friendly Home away - Beautiful Views [](https://www.expedia.com/Las-Cruces-Hotels-Agua-Caliente-Family-Friendly-Home-Away-Beautiful-Views.h91653080.Hotel-Information) Las Cruces 8.8/10 Excellent (16 reviews) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) antoinette R. $460 nightly $495 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Agua-Caliente-Family-Friendly-Home-Away-Beautiful-Views.h91653080.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511641/616f59b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511641/2fd256cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511641/80a932b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119520000/119511700/119511641/04ccdf73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 bd/2bth near NMSU and Memorial Medical Center [](https://www.expedia.com/Las-Cruces-Hotels-2-Bd2bth-Near-NMSU-And-Memorial-Medical-Center.h119511641.Hotel-Information) Las Cruces 10/10 Exceptional (3 reviews) "Wonderful nights sleep says it all - w hugs waiting in the kitchen kuerig coffee , eggs , English muffins to get us started on our way 10 stars " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita S. $245 nightly $275 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-2-Bd2bth-Near-NMSU-And-Memorial-Medical-Center.h119511641.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653046/242f8978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653046/244585a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653046/e7c1d74c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653046/1c818bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MS · Comfortable New Home with Organ Mountain Views! [](https://www.expedia.com/Las-Cruces-Hotels-MS-Comfortable-New-Home-With-Organ-Mountain-Views.h91653046.Hotel-Information) Las Cruces 10/10 Exceptional (5 reviews) "Thank you for letting us stay in youre beautiful home. We enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LIZA M. $356 nightly $382 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-MS-Comfortable-New-Home-With-Organ-Mountain-Views.h91653046.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/122000000/121680000/121677600/121677584/0ece43f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121680000/121677600/121677584/e4951708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121680000/121677600/121677584/cda877ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121680000/121677600/121677584/5584ab98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern 4BR, 3 King Beds + Full Near Red Hawk [](https://www.expedia.com/Las-Cruces-Hotels-Modern-4BR.h121677584.Hotel-Information) Las Cruces 10/10 Exceptional (2 reviews) "Great house for small office get together for the holidays. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kiera M. $337 nightly $365 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Modern-4BR.h121677584.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653060/2acf67b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653060/ad73223e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653060/f8e8cf3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653060/c0af40ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Toluca · Comfortable 4/3.5 private home near parks [](https://www.expedia.com/Las-Cruces-Hotels-Toluca-Comfortable-435-Private-Home-Near-Parks.h91653060.Hotel-Information) Las Cruces 9.2/10 Wonderful (16 reviews) "Great stay and great host!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Transitions Group V. $381 nightly $410 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Toluca-Comfortable-435-Private-Home-Near-Parks.h91653060.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/123000000/122840000/122835600/122835513/972aab91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122840000/122835600/122835513/25de3c2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/123000000/122840000/122835600/122835513/cd91f665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/123000000/122840000/122835600/122835513/77cdc42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Vacation Rental [](https://www.expedia.com/Las-Cruces-Hotels-Luxury-Vacation-Rental.h122835513.Hotel-Information) Las Cruces 10/10 Exceptional (1 review) "Patricia was welcoming. We were in town to celebrate a graduation and the home was lovely and there was enough room for the family to gather. The rooms were spacious and the amenities were not too overwhelming. We enjoyed our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lenora A. $495 nightly $539 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Luxury-Vacation-Rental.h122835513.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/2e3e8863.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/c1e00df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/533d2cda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/93854e6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis [](https://www.expedia.com/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information) Las Cruces 9.0/10 Wonderful (15 reviews) "Clean, well furnished and stocked linens and essentials. Pet friendly and large enough for family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jo Anne C. $195 nightly $211 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-02&endDate=2026-04-03®ionId=132684&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-17&d1=2026-06-17&endDate=2026-06-20&d2=2026-06-20&lodging=APARTMENT) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-17&d1=2026-06-17&endDate=2026-06-20&d2=2026-06-20&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-17&d1=2026-06-17&endDate=2026-06-20&d2=2026-06-20&lodging=CONDO) Cottages [](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-17&d1=2026-06-17&endDate=2026-06-20&d2=2026-06-20&lodging=COTTAGE) Villas [](https://www.expedia.com/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-17&d1=2026-06-17&endDate=2026-06-20&d2=2026-06-20&lodging=VILLA) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Vacation-Rentals.d132684.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Vacation-Rentals.d132684.Travel-Guide-VacationRentals) ## Top Mesilla Hotel Reviews ![Hampton Inn & Suites Las Cruces I-25](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665185/fc08ee64_y.jpg) ### Hampton Inn & Suites Las Cruces I-25 8/10 Good "Clean room" [](https://expedia.com/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-25.h1665185.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain](https://images.trvl-media.com/lodging/1000000/80000/75400/75365/e54f14db_y.jpg) ### La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain 10/10 Excellent "Our stay was great! We have stayed here before and chose this La Quinta again because we liked it previously. Easy to get to, nice property. Great staff. Very helpful and friendly. Recommended. " [](https://expedia.com/Las-Cruces-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Las-Cruces-Organ-Mountain.h75365.Hotel-Information) ![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 10/10 Excellent "Comfortable and clean. " [](https://expedia.com/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Hampton Inn & Suites Las Cruces I-10](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/dec3042f_y.jpg) ### Hampton Inn & Suites Las Cruces I-10 10/10 Excellent "Comfortable and quiet" [](https://expedia.com/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ![Best Western Mission Inn](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/798cead2_y.jpg) ### Best Western Mission Inn 8/10 Good "Everything was great except for the driveway. It was terribly rough and full of potholes." [](https://expedia.com/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Ramada Hotel & Conference Center by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/10000/3900/3871/1a82ee39_y.jpg) ### Ramada Hotel & Conference Center by Wyndham Las Cruces 10/10 Excellent "Professional services n great staff!" [](https://expedia.com/Las-Cruces-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-Las-Cruces.h3871.Hotel-Information) ![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 6/10 Okay "Staff was great, but the facilities were in really poor repair. The hot water heater was broken on day one, barely warm showers. The pool heater is busted, but you could go swim next door. The bathroom tiles were loose, they would shift when standing on them…there was no grout between the tiles either. A rusty spot on the wall where a pipe was coming through. It’s a cheap stay and you’ll know why when you get there. " [](https://expedia.com/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Days Inn by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/b4a415ed_y.jpg) ### Days Inn by Wyndham Las Cruces 10/10 Excellent "👍" [](https://expedia.com/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) ![Drury Inn & Suites Las Cruces](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/46263956_y.jpg) ### Drury Inn & Suites Las Cruces 10/10 Excellent "Upgrades to a suite. Loved the happy hour and dinner. Great stay" [](https://expedia.com/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ## Find out more about Mesilla **Everything you need to know about Mesilla vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesilla vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesilla vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Mesilla vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Mesilla. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesilla in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $133 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Mesilla rentals** At Expedia, we put the best Mesilla vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesilla vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Mesilla ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) - [Vacation Homes in Mesilla ](https://expedia.com/Mesilla-Private-Vacation-Homes.d132684-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Mesilla ](https://expedia.com/Mesilla-Apartments.d132684-aaApartments.Travel-Guide-Accommodation) - [Cottages in Mesilla ](https://expedia.com/Mesilla-Cottages.d132684-aaCottages.Travel-Guide-Accommodation) - [Condo Rentals in Mesilla ](https://expedia.com/Mesilla-Condos.d132684-aaCondos.Travel-Guide-Accommodation) - [Villas in Mesilla ](https://expedia.com/Mesilla-Villas.d132684-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in Mesilla ](https://expedia.com/Mesilla-Guest-Houses.d132684-aaGuestHouses.Travel-Guide-Accommodation) - [Motels in Mesilla ](https://expedia.com/Mesilla-Motels.d132684-aaMotels.Travel-Guide-Accommodation) - [Farmstay in Mesilla ](https://expedia.com/Mesilla-Agritourism.d132684-aaAgritourism.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find a vacation rental in Mesilla? 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