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Find Business Hotels in Midtown, TX

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Check availability on Midtown Business Hotels

Our top choices for Midtown business-friendly hotels

Outdoor dining
Fully stocked, Modern & Cosy Studio with Patio. Best Location! Walk Everywhere!

Fully stocked, Modern & Cosy Studio with Patio. Best Location! Walk Everywhere!

Midtown
9.8 out of 10, Exceptional, (77)
"Great place, great location. Easy communication! "
United States
Carly R.
$153 nightly
The price is $176
Dec 21 - Dec 22
Total with taxes and fees
Fully stocked, Modern & Cosy Studio with Patio. Best Location! Walk Everywhere!
Exterior
La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

3.5 star property
Midtown
9.8 out of 10, Exceptional, (541)
"great neighborhood, friendly staff, and delicious breakfast"
United States
Anna
$168 nightly
The price is $197
Dec 22 - Dec 23
Total with taxes and fees
La Maison in Midtown an urban B&B
Lobby
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4.0 star property
Downtown Houston
8.4 out of 10, Very Good, (3926)
"Hotel was beautiful, room was great for the price"
United States
Sonya
$79 nightly
The price is $92
Dec 12 - Dec 13
Total with taxes and fees
Club Quarters Hotel Downtown, Houston
Sundeck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 star property
Texas Medical Center
8.4 out of 10, Very Good, (1733)
"Loved the room, clean, friendly staff. Would reccomend :)"
United States
Rolando
$94 nightly
The price is $110
Dec 28 - Dec 29
Total with taxes and fees
Hilton Houston Plaza/Medical Center
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3601)
"Everything about our stay was excellent. "
United States
Clarence
$123 nightly
The price is $144
Dec 16 - Dec 17
Total with taxes and fees
Blossom Hotel Houston, Curio Collection by Hilton
Interior
Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel

2.5 star property
Southeast Houston
9.4 out of 10, Exceptional, (51)
"I had a good stay. "
United States
Aliya
$80 nightly
The price is $94
Jan 1 - Jan 2, 2026
Total with taxes and fees
Best Western Plus Pearland/Houston Medical Center Hotel
Free daily buffet breakfast
Hyatt Place Houston/Sugar Land

Hyatt Place Houston/Sugar Land

3.0 star property
First Colony
8.8 out of 10, Excellent, (1776)
"Great location "
United States
Jessica
$80 nightly
The price is $92
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hyatt Place Houston/Sugar Land
Terrace/patio
Courtyard by Marriott Houston Intercontinental Airport

Courtyard by Marriott Houston Intercontinental Airport

3.0 star property
Houston
9.0 out of 10, Wonderful, (1071)
"Great place to stay "
United States
Hammed Sirleau
$98 nightly
The price is $115
Dec 13 - Dec 14
Total with taxes and fees
Courtyard by Marriott Houston Intercontinental Airport
Deluxe Suite, 1 King Bed, Non Smoking (Deluxe Family Suite) | Premium bedding, desk, laptop workspace, iron/ironing board
La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E

3.0 star property
Humble
7.8 out of 10, Good, (2486)
"Great place to stay! Staff are friendly, rooms were clean and quiet. "
Canada
Elizabeth
$63 nightly
The price is $74
Jan 4 - Jan 5, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Houston Bush Intl Airpt E
City view
Hyatt Regency Houston Downtown

Hyatt Regency Houston Downtown

4.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1095)
"Staff is great!"
United States
Paula
$149 nightly
The price is $174
Dec 19 - Dec 20
Total with taxes and fees
Hyatt Regency Houston Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Midtown Hotel Reviews

Hilton Americas-Houston

Hilton Americas-Houston

10/10 Excellent
"This hotel is jaw dropping. In the heart of all the activities. Park view room was great. Best hotel buffet breakfast we have ever had!"
David 2-night trip
Posted 23 hours ago
Hilton Americas-Houston

Frequently asked questions

Why book your business-friendly hotel in Midtown with Expedia?
With handy amenities like meeting rooms, housekeeping and free WiFi, our business-friendly accommodations come with all you'll need to get the job done — and then unwind! Enter your preferred travel dates and destination and we'll help you with the rest.
How can I find cheap business-friendly hotels in Midtown?
Select the "business friendly" filter, located just under the "traveler experience" heading, to find cheap business-friendly hotels in Midtown. Then fine-tune your search by your preferred hotel star rating and budget. Basing yourself outside the city center can also help you save.

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