Ostiense Vacations from $885

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
CC Palace Hotel Roma

CC Palace Hotel Roma

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,382, price is now $885 per person
$885
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (356 reviews)
I loved the service from the minute we arrived to the minute we checked out. The staff are friendly and jovial. The facility was topnotch.

Reviewed on Sep 22, 2025

JC Hotel

JC Hotel

4 out of 5
Fonte Ostiense
Save 100% on your flight
Price was $1,757, price is now $928 per person
$928
per person
Jan 1 - Jan 8
found 1 hour ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8/10 Very Good! (133 reviews)
Monastero dei Santi

Monastero dei Santi

5 out of 5
Municipio I
Save 100% on your flight
Price was $4,642, price is now $2,940 per person
$2,940
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
10/10 Exceptional! (24 reviews)
Amazing time. A great 8 days! Thank you! A rare view of Rome!!

Reviewed on Oct 8, 2025

Nobu Hotel Roma

Nobu Hotel Roma

Rome City Centre
Save 100% on your flight
Price was $4,133, price is now $2,656 per person
$2,656
per person
Jan 1 - Jan 8
found 1 hour ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
No reviews
Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Price was $3,367, price is now $2,171 per person
$2,171
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.6/10 Exceptional! (319 reviews)
Could not be faulted. We thoroughly enjoyed our stay which was made even better when the hotel realised it was our Silver Wedding celebration holiday and left a lovely present in our room for us. Attentive detail to the finest degree.

Reviewed on Oct 23, 2025

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7, Rome, RM
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $191 total per night from Nov 17 to Nov 18
$191 total
Nov 17 - Nov 18
Total with taxes and fees
8.6/10 Excellent! (1,892 reviews)
Have stayed in this hotel many times over the last 15 years. Disappointing the very slow draining shower which wasn’t fixed despite requesting it to be. Will still stay again in future as it is such a good location / classic Rome.

Reviewed on Oct 18, 2025

Hotel Quirinale
citizenM Rome Isola Tiberina

citizenM Rome Isola Tiberina

4 out of 5
LUNGOTEVERE DE CENCI 5-8, Rome, RM
Fully refundableReserve now, pay when you stay
$194 nightly
The price is $231 total per night from Nov 23 to Nov 24
$231 total
Nov 23 - Nov 24
Total with taxes and fees
9.4/10 Exceptional! (705 reviews)
Great overall except for parking

Reviewed on Oct 16, 2025

citizenM Rome Isola Tiberina
Hotel Delle Nazioni

Hotel Delle Nazioni

4 out of 5
Via Poli 7, Rome, RM
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $202 total per night from Nov 11 to Nov 12
$202 total
Nov 11 - Nov 12
Total with taxes and fees
8.8/10 Excellent! (1,018 reviews)
Excellent location and walkable to many keys attractions. Outstanding front desk staff and very clean hotel with many breakfast items on their buffet table. I would highly recommend this hotel.

Reviewed on Oct 14, 2025

Hotel Delle Nazioni
See all 15,744 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Basilica of St. Paul Outside the Walls

Basilica of St. Paul Outside the Walls

4.5/5(352 reviews)

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls
#GoodEats “Bucatini all’Amatriciana” 😋🤤 Taste of home ❤️

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the churches and notable monuments in this vibrant area.

Roma Tre University

Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Picture 1 for Activity Rome: Vatican Museums, Sistine Chapel, and Basilica Tour

Vatican Museums, Sistine Chapel & St. Peter's Square Tour

$92
per adult
86% of travellers recommend
Vatican Museums, Sistine Chapel & St. Peter's Square Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.