Find hotels in Otay Mesa West, San Diego

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Discover Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Best Western Plus Marina Gateway Hotel

3.5 star property
6.5 mi from Otay Mesa West
9.2 out of 10, Wonderful, (3491)
"Clean room nice staff right off of the freeway. "
United States
Olivia
$116 nightly
The price is $128
Dec 14 - Dec 15
Total with taxes and fees
Best Western Plus Marina Gateway Hotel

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 11.2 mi from Otay Mesa West
8.8 out of 10, Excellent, (2084)
"Room was spotless and location great. "
United States
James
$139 nightly
The price is $161
Dec 14 - Dec 15
Total with taxes and fees
Palihotel San Diego Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
Marina District, 11.1 mi from Otay Mesa West
9.0 out of 10, Wonderful, (2696)
"Clean facilities and friendly staff!"
United States
EMMA
$154 nightly
The price is $179
Dec 12 - Dec 13
Total with taxes and fees
The Horton Grand, Downtown/Gaslamp Quarter

Wyndham San Diego Bayside

4.0 star property
11.9 mi from Otay Mesa West
8.4 out of 10, Very Good, (6069)
"Always an amazing stay"
United States
Jana
$160 nightly
The price is $186
Dec 9 - Dec 10
Total with taxes and fees
Wyndham San Diego Bayside

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 11 mi from Otay Mesa West
9.0 out of 10, Wonderful, (1228)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
$137 nightly
The price is $159
Dec 14 - Dec 15
Total with taxes and fees
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 10.9 mi from Otay Mesa West
9.0 out of 10, Wonderful, (3141)
"Great stay"
United States
Laurence
$210 nightly
The price is $243
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hard Rock Hotel San Diego

Best Western Plus Suites Hotel Coronado Island

2.5 star property
10.7 mi from Otay Mesa West
8.8 out of 10, Excellent, (1001)
"Good to spend a night or two-- nice staff-- friendly ad awesome breakfast"
United States
MICHELE
$157 nightly
The price is $173
Dec 14 - Dec 15
Total with taxes and fees
Best Western Plus Suites Hotel Coronado Island

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 11.3 mi from Otay Mesa West
9.0 out of 10, Wonderful, (1006)
"Great room, clean, spacious and quiet. "
United States
Maria
$111 nightly
The price is $126
Dec 9 - Dec 10
Total with taxes and fees
Gaslamp Plaza Suites

The Bristol Hotel San Diego

3.5 star property
11.5 mi from Otay Mesa West
8.6 out of 10, Excellent, (1442)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
$140 nightly
The price is $162
Dec 20 - Dec 21
Total with taxes and fees
The Bristol Hotel San Diego

The Sofia Hotel

3.5 star property
11.5 mi from Otay Mesa West
8.4 out of 10, Very Good, (1652)
"Great location and history to the hotel "
United States
Stephanie
$101 nightly
The price is $117
Dec 9 - Dec 10
Total with taxes and fees
The Sofia Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 11 mi from Otay Mesa West
9.4 out of 10, Exceptional, (1007)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
$140 nightly
The price is $163
Dec 26 - Dec 27
Total with taxes and fees
Staypineapple, Hotel Z, Gaslamp San Diego

Bay Club Hotel & Marina

3.5 star property
13.7 mi from Otay Mesa West
9.2 out of 10, Wonderful, (3171)
"Great stay and location!"
United States
Jason
$121 nightly
The price is $139
Dec 8 - Dec 9
Total with taxes and fees
Bay Club Hotel & Marina

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
North Pacific Beach, 18.5 mi from Otay Mesa West
8.0 out of 10, Very Good, (1424)
"Great place We will stay here again. "
United States
Derek
$98 nightly
The price is $112
Dec 14 - Dec 15
Total with taxes and fees
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Glorietta Bay Inn Coronado Island

3.5 star property
10.1 mi from Otay Mesa West
8.6 out of 10, Excellent, (1000)
"Great location Main Street. Orange ave is literally to the right of hotel walking to everything beautiful setting cozy rooms feels like your in a villa with small little outside rooms with patio or balcony Breakfast on the patio nice pool and professional staff "
United States
Diane
$243 nightly
The price is $270
Dec 8 - Dec 9
Total with taxes and fees
Glorietta Bay Inn Coronado Island

Marriott Marquis San Diego Marina

4.0 star property
Marina District, 11.2 mi from Otay Mesa West
9.2 out of 10, Wonderful, (1939)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Dec 18 - Dec 19
Total with taxes and fees
Marriott Marquis San Diego Marina

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 11 mi from Otay Mesa West
9.0 out of 10, Wonderful, (1159)
"Amenities and location were great. "
United States
Julie
$204 nightly
The price is $237
Dec 14 - Dec 15
Total with taxes and fees
Margaritaville Hotel San Diego Gaslamp Quarter

Heritage Inn La Mesa

2.0 star property
13.6 mi from Otay Mesa West
7.0 out of 10, Good, (1189)
"room was clean and staff very friendly"
United States
Charles
$57 nightly
The price is $63
Dec 10 - Dec 11
Total with taxes and fees
Heritage Inn La Mesa

Urban Boutique Hotel

3.0 star property
Little Italy, 12 mi from Otay Mesa West
8.6 out of 10, Excellent, (1277)
"Locations is excellent and the front desk lady was friendly "
Canada
Ju
$125 nightly
The price is $142
Dec 17 - Dec 18
Total with taxes and fees
Urban Boutique Hotel

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
11.8 mi from Otay Mesa West
8.8 out of 10, Excellent, (717)
"Great staff, great location, great value. "
United States
Juan
$103 nightly
The price is $120
Dec 15 - Dec 16
Total with taxes and fees
The DEXTRO Little Italy, BW Premier Collection

La Pensione Hotel

3.0 star property
Little Italy, 12 mi from Otay Mesa West
8.6 out of 10, Excellent, (1903)
"Friendly staff, very nice room, great location!"
United States
Lisa
$149 nightly
The price is $169
Dec 8 - Dec 9
Total with taxes and fees
La Pensione Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa West Hotel Reviews

Find out more about Otay Mesa West

Top reasons to visit Otay Mesa West

  • Family-Friendly Activities: Otay Mesa West offers a variety of entertainment options suitable for all ages, including local theaters and vibrant shopping centers.
  • Outdoor Adventures: Enjoy lush urban parks and nearby Spring Valley for outdoor fun and relaxation.
  • Cultural Experiences: Immerse yourself in the vibrant local culture, sampling unique cuisine and friendly neighborhood vibes.
  • Diverse Accommodations: Find pet-friendly hotels and fully-equipped studio apartments catering to various traveler needs.
  • Convenient Location: Otay Mesa West provides easy access to San Diego's attractions and beautiful beaches.

Find great hotels near Otay Mesa West

Discover a variety of accommodation options in Otay Mesa West, San Diego, perfect for all kinds of travelers. From pet-friendly hotels to fully-equipped studio apartments, you’ll find the ideal place to relax after a day of exploration. Whether you need a business-friendly environment or a family-oriented space, Otay Mesa West has you covered with comfortable lodging that caters to your unique needs.

  • Best Western Plus Marina Gateway Hotel: Nestled just 7 miles from Otay Mesa West, the Best Western Plus Marina Gateway Hotel offers a family-friendly and eco-certified experience. This hotel is perfect for eco-conscious travelers seeking comfort and convenience. Amenities for children include a mini-golf course, a free crib option, and a pool designed with kids in mind. The property’s commitment to sustainability ensures an enjoyable stay while caring for the environment, making it an ideal choice for families looking to blend fun with eco-friendly practices.
  • Manchester Grand Hyatt San Diego: Located 11 miles away from Otay Mesa West, the Manchester Grand Hyatt San Diego is a luxurious 4-star hotel that caters to adventure seekers and business travelers alike. With an array of amenities including a comprehensive business center and multiple meeting rooms, this hotel is perfect for corporate guests. Adventure enthusiasts can indulge in nearby surfing, kayaking, and hiking activities, while pet owners will appreciate the pet-friendly policy. This hotel seamlessly combines business and leisure, making it a top choice for diverse travelers.
  • Ramada by Wyndham San Diego National City: Situated 7 miles from Otay Mesa West, the Ramada by Wyndham San Diego National City is a 3-star hotel that offers a delightful blend of pet-friendly accommodations and adventure opportunities. With a 24-hour business center and meeting spaces, it serves the needs of business travelers efficiently. Guests can explore thrilling nearby activities such as rafting and snorkeling. The hotel’s pet policy ensures your furry friends are welcome, making it an excellent option for travelers looking to adventure with their pets.

Where to stay near Otay Mesa West

Otay Mesa West offers a delightful blend of family-friendly attractions and vibrant local culture. Explore the charming streets of this residential neighborhood, where you can enjoy a mix of entertainment options and friendly faces. Nearby Spring Valley provides additional opportunities for outdoor fun and relaxation. Whether you're indulging in local cuisine or discovering the area's unique vibe, your vacation in and around Otay Mesa West promises unforgettable experiences for travelers of all ages.

  • San Diego: As the vibrant city hosting Otay Mesa West, San Diego is a must-visit destination known for its beautiful coastline and rich culture. The city offers a plethora of family-friendly attractions such as the world-famous San Diego Zoo and LEGOLAND. Visitors can enjoy outdoor activities year-round, from sunbathing on the beaches to exploring Balboa Park's gardens and museums. Shopping enthusiasts will appreciate the diverse shopping centers and resorts, making it a great spot for both relaxation and adventure.
  • Otay: Just a mile away from Otay Mesa West, Otay is a lively neighborhood that combines family fun with cultural experiences. Known for its entertainment-themed venues, visitors can indulge in theater performances or explore the local shopping mall. Otay boasts attractions like theme parks and symbolic landmarks, offering plenty of entertainment for all ages. Whether you're looking to immerse yourself in the local culture or enjoy a day of family activities, Otay provides a unique and engaging experience.
  • South San Diego: Located a mile from Otay Mesa West, South San Diego is perfect for those seeking a romantic getaway or family-friendly adventures. The area features resorts and campgrounds, making it ideal for outdoor enthusiasts. Visitors can explore event venues or relax on the nearby family beaches. With its city-themed charm and variety of recreational options, South San Diego offers a delightful blend of relaxation and excitement, ensuring a memorable vacation experience.

Things to do near Otay Mesa West

Otay Mesa West is perfect for family-friendly and entertainment-themed vacations. Visitors can enjoy a variety of activities, including catching a show at a local theater, exploring vibrant shopping centers, and browsing through popular shopping malls. This area offers a lively atmosphere that caters to all ages, making it an ideal destination for a fun-filled getaway.

Shopping

For shopping in Otay Mesa West, visit Las Americas Premium Outlets, just 2 miles away, offering a variety of entertainment and family-friendly options. Chula Vista Center, 4 miles away, features similar vibes, while Otay Ranch Town Center, 6 miles away, provides a charming shopping experience for all.

Recreation

Experience the excitement at Petco Park, where you can catch a game and enjoy the vibrant sports atmosphere. For a different vibe, The Rady Shell at Jacobs Park offers live music events. If you prefer outdoor activities, play a round at the scenic Eastlake Country Club.

Adventure

At Sesame Place San Diego, located 3 miles from Otay Mesa West, enjoy thrilling water slides and family-friendly attractions. White Water Canyon, also 3 miles away, offers exciting water adventures. For a unique experience, visit Sky Zone San Diego, 8 miles away, where you can bounce and flip in a trampoline paradise.

Nightlife

Experience the vibrant nightlife in Otay Mesa West. Start your evening at the North Island Credit Union Amphitheatre for live performances. For a fun twist, head to Len Moore Skate Park and Atlantis Laser Tag, both offering exciting arcade adventures just a short drive away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Otay Mesa West

To save money on your trip to Otay Mesa West, consider visiting from November to January when hotel prices are lower, and aim for a Tuesday stay to avoid high Saturday rates. Use Expedia’s search tool to find budget-friendly accommodations, and filter for Eco-certified hotels for sustainable options. Combine your hotel, flights, and activities in an Expedia package for additional savings, and join the One Key membership for exclusive discounts and rewards. Don’t forget to explore free attractions and use public transport to get around affordably.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Otay Mesa West are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Otay Mesa West is Tuesday. The most expensive day to stay around Otay Mesa West is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool gives you the flexibility to choose your budget, desired location, and additional preferences. You can arrange your search results to display prices from lowest to highest, making it easy to find the most affordable hotels first. Additionally, you can refine your search by hotel type—if you check the Eco-certified filter, you’ll see a selection of sustainable and environmentally friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel stay in Otay Mesa West with your flights and activities through an Expedia package.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Otay Mesa West

Otay Mesa West is perfect for family and city-themed vacations, offering a blend of entertainment and culture. Visitors can explore beautiful beaches, enjoy the lush urban parks, and attend events at local conference venues. This area caters to travelers seeking outdoor adventures and urban experiences, making it an ideal spot for those looking to immerse themselves in the vibrant culture and scenic landscapes of San Diego.

  • San Ysidro Border Crossing: Experience the bustling energy at one of the busiest border crossings in the world, located a mere 3 miles from Otay Mesa West. This civic area offers a unique glimpse into cross-border culture with friendly locals and sunny weather, making it a great spot for families and business travelers alike.
  • San Diego Convention Center: Situated 11 miles away, this premier event venue is a hub for conferences and exhibitions. The modern architecture and vibrant atmosphere make it a perfect place to network and engage with diverse industries while enjoying the scenic views of the San Diego waterfront.
  • Coronado Beach: Just 11 miles from Otay Mesa West, this beautiful beach is known for its golden sands and laid-back vibe. It's an ideal spot to relax, sunbathe, and enjoy stunning sunsets, making it a must-visit for beach lovers.

Best time to go to Otay Mesa West

The best time to visit Otay Mesa West can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Otay Mesa West falls in August, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature around Otay Mesa West falls in February, visitor numbers are slightly low and weather is sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.4°F (14.1°C)Light RainSunnySlightly LowSlightly Low
February56.8°F (13.8°C)Light RainSunnySlightly LowAverage
March58.1°F (14.5°C)No RainMostly SunnyAverageAverage
April60.6°F (15.9°C)No RainSunnyAverageAverage
May62.6°F (17.0°C)No RainSunnyAverageAverage
June66.4°F (19.1°C)No RainSunnySlightly HighSlightly High
July70.5°F (21.4°C)No RainSunnySlightly HighSlightly High
August72.3°F (22.4°C)No RainSunnySlightly HighSlightly High
September72.0°F (22.2°C)No RainSunnyAverageAverage
October68.2°F (20.1°C)No RainSunnyAverageAverage
November62.6°F (17.0°C)No RainSunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Otay Mesa West

When visiting Otay Mesa West in San Diego, you have convenient access to two major airports. San Diego International Airport (SAN) is located 14 miles away, with nearby hotels like the luxurious Pendry San Diego and The US Grant, both 3 miles from the airport. Another option is Tijuana International Airport (TIJ), only 5 miles away, with excellent hotels such as Quartz Hotel & SPA and Real Inn Tijuana, both 3 miles from TIJ. For those considering Carlsbad, McClellan-Palomar Airport (CLD) is 40 miles away, offering upscale accommodations like the Park Hyatt Aviara Resort, just 2 miles from the airport.

Frequently asked questions

What are the best family hotels in Otay Mesa West?
The Best Western Chula Vista/Otay Valley Hotel is an excellent choice for families seeking a comfortable and convenient stay. This hotel offers a refreshing pool area, superb for kids to splash around while parents relax nearby. The property also provides cribs at no extra charge, making it easy for families traveling with infants. Guests appreciate the daily housekeeping service that keeps everything tidy, along with microwaves in the rooms, ensuring you can prepare quick snacks for your little ones.

Another family-friendly option is the Motel 6 San Diego, CA - Southbay. This hotel is particularly accommodating for families with children, offering connecting rooms, which allow for easy supervision and bonding time. Young travelers can enjoy free stays, adding great value for families on a budget. Like the Best Western, this property also features housekeeping services and microwaves, making it convenient for families to settle in and feel at home.
What hotels in Otay Mesa West offer free breakfast?
The Best Western Chula Vista/Otay Valley Hotel is a fantastic choice for travelers seeking comfort and convenience in Otay Mesa West. This hotel offers a delightful start to your day with a complimentary continental breakfast, ensuring you and your family can fuel up before heading out on your adventures.
What are the best budget hotels in Otay Mesa West?
The Best Western Chula Vista/Otay Valley Hotel is a fantastic budget-friendly option in Otay Mesa West, offering families and travelers a comfortable stay with a variety of amenities. Guests appreciate the outdoor pool, great for splashing around after a day of exploration, and the complimentary continental breakfast ensures a great start to your day without breaking the bank.

This hotel also caters to families, providing free cribs and accessible parking, making it easy for parents traveling with young children. The fitness center allows adults to stay active, while free WiFi keeps everyone connected. With a customer review rating of 7.8, it's clear that many have found it to be a reliable choice for quality and convenience.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Otay Mesa West hotel for you.
How can I save on a Otay Mesa West hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Otay Mesa West hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Otay Mesa West hotel?
Hotel prices in Otay Mesa West often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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