Find hotels in Perryville, MO from $63

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Our top choices for Perryville hotels

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
Perryville
9.2 out of 10, Wonderful, (538)
"Clean room and pleasant staff"
United States
David
$87 nightly
The price is $100
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express & Suites Perryville by IHG

Super 8 by Wyndham Perryville

2.0 star property
Perryville
8.4 out of 10, Very Good, (937)
"The room was spotless, and the staff was extremely patient. Each one was very helpful. It was easy to get a good night's sleep - the building was very quiet."
United States
Cynthia
$62 nightly
The price is $71
Dec 25 - Dec 26
Total with taxes and fees
Super 8 by Wyndham Perryville

Quality Inn Perryville I-55

2.5 star property
Perryville
6.6 out of 10, (124)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
$69 nightly
The price is $79
Dec 17 - Dec 18
Total with taxes and fees
Quality Inn Perryville I-55

Days Inn by Wyndham Perryville

2.0 star property
Perryville
6.8 out of 10, (415)
"Was a nice place."
United States
Lesliee
$55 nightly
The price is $63
Dec 21 - Dec 22
Total with taxes and fees
Days Inn by Wyndham Perryville

Urban Lofts

3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
$208 nightly
The price is $238
Dec 31 - Jan 1, 2026
Total with taxes and fees
Urban Lofts

Holiday Inn Express Hotel & Suites Sparta by IHG

2.5 star property
Sparta
9.2 out of 10, Wonderful, (368)
"Bed was comfortable, breakfast was a 10/10! "
United States
Junior
$96 nightly
The price is $107
Dec 26 - Dec 27
Total with taxes and fees
Holiday Inn Express Hotel & Suites Sparta by IHG

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1006)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
$83 nightly
The price is $88
Dec 10 - Dec 11
Total with taxes and fees
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (510)
"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
$107 nightly
The price is $119
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (661)
"Great place "
United States
GUY
$78 nightly
The price is $85
Jan 4 - Jan 5, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
Ste Genevieve
8.8 out of 10, Excellent, (610)
"Excellent "
United States
James
$74 nightly
The price is $83
Dec 14 - Dec 15
Total with taxes and fees
Microtel Inn & Suites by Wyndham Sainte Genevieve

Baymont by Wyndham Chester IL

2.5 star property
Chester
8.6 out of 10, Excellent, (350)
"The room was clean and the staff were friendly. "
United States
RODNEY
$71 nightly
The price is $79
Dec 26 - Dec 27
Total with taxes and fees
Baymont by Wyndham Chester IL

Town House Inn

2.5 star property
Jackson
7.6 out of 10, Good, (422)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
$68 nightly
The price is $74
Dec 15 - Dec 16
Total with taxes and fees
Town House Inn

Tru By Hilton Cape Girardeau

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (99)
"It was a nice stay"
United States
Douglas
$87 nightly
The price is $99
Dec 15 - Dec 16
Total with taxes and fees
Tru By Hilton Cape Girardeau

The Conner House B&B

3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19)
"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
$145 nightly
The price is $161
Dec 16 - Dec 17
Total with taxes and fees
The Conner House B&B

Triangle Inn Motel

2.0 star property
Ste Genevieve
8.0 out of 10, Very Good, (42)
"The staff was very accommodating."
United States
Herbert
$85 nightly
The price is $95
Dec 10 - Dec 11
Total with taxes and fees
Triangle Inn Motel

Briarwood Inn of Sparta

2.5 star property
Sparta
7.4 out of 10, Good, (122)
"My stay was excellent. The owner even gave me a ride to church and I am very thankful"
United States
LaQuana
$75 nightly
The price is $83
Dec 10 - Dec 11
Total with taxes and fees
Briarwood Inn of Sparta

Comfort Suites Jackson-Cape Girardeau

2.5 star property
Jackson
8.2 out of 10, Very Good, (739)
"Dirty "
United States
Jon
$80 nightly
The price is $86
Dec 28 - Dec 29
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau

Madison Inn Lodge

2.5 star property
Fredericktown
7.6 out of 10, Good, (297)
"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
$78 nightly
The price is $85
Jan 1 - Jan 2, 2026
Total with taxes and fees
Madison Inn Lodge

Sparta Motel

2.0 star property
Sparta
4.4 out of 10, (66)
"Nice hotel, clean, huge pool"
United States
Stacey
$66 nightly
The price is $73
Dec 10 - Dec 11
Total with taxes and fees
Sparta Motel
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Stay near popular Perryville attractions

Perryville and related destinations

Historic battlefields and the charming downtown district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Center and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

Arched train bridge

Top Perryville Hotel Reviews

More cheap stays in Perryville

Hotels in Perryville with star-rating

Find out more about Perryville

Top reasons to visit Perryville

  • Scenic Outdoor Activities: Enjoy beautiful parks and recreational activities, perfect for nature lovers and adventure seekers.
  • Rich Historical Attractions: Explore local shrines, memorials, and historic sites that showcase Perryville's fascinating history.
  • Charming Lakes: Experience the serene beauty of nearby lakes, ideal for relaxation and romantic getaways.
  • Family-Friendly Options: Discover attractions catering to families, ensuring a fun experience for visitors of all ages.
  • Diverse Accommodations: Find a variety of hotels and suites that cater to all preferences, including pet-friendly and LGBTQIA-welcoming options.

Find great hotels in and around Perryville

Explore a variety of hotel accommodation options in Perryville, Missouri, perfect for your vacation needs. Whether you are looking for pet-friendly stays, business-themed facilities, or LGBTQIA welcoming environments, Perryville has something for everyone. Discover the best hotels and suites in the area by checking out reviews and amenities that cater to all types of travelers. Enjoy a comfortable and memorable experience during your visit to this charming town.

  • Super 8 by Wyndham Perryville: Experience the comfort and convenience of Super 8 by Wyndham Perryville, a welcoming motel designed for both business travelers and pet lovers. Located in the heart of Perryville, this property offers essential amenities including a Business Center and Meeting Room, catering to your professional needs. Ideal for those traveling with furry companions, the hotel has a pet-friendly policy that allows certain pets on-site, making it a great choice for guests who want to bring their pets along. With its focus on practicality and comfort, Super 8 ensures a pleasant stay for all visitors.
  • Holiday Inn Express & Suites Perryville by IHG: The Holiday Inn Express & Suites Perryville by IHG stands out as a modern hotel that embraces inclusivity and community. This property is not only pet-friendly but also LGBTQIA welcoming, making it an ideal choice for diverse travelers. With a focus on business amenities such as an accessible Business Center and Meeting Room, guests can easily balance work and leisure. Located conveniently in Perryville, this hotel combines comfort with a commitment to providing an inviting atmosphere for everyone.
  • Baymont by Wyndham Chester IL: Just a short drive from Perryville, Baymont by Wyndham Chester IL offers a cozy retreat for both business travelers and pet owners. This hotel features a 24-hour Business Center, ensuring that you have access to all necessary resources at any time. With a pet-friendly policy limited to dogs, guests can enjoy their stay without leaving their furry friends behind. The Baymont combines comfort, functionality, and a welcoming vibe, making it a perfect choice for your stay near Perryville.

Where to stay in and around Perryville

Perryville, Missouri, is a charming city perfect for outdoor enthusiasts and romantic getaways. Visitors can explore scenic landscapes and enjoy a variety of recreational activities in the area. Nearby towns offer a friendly atmosphere and convenient access to family-friendly attractions. With its easy commute and vibrant local culture, Perryville is an ideal destination for those seeking a blend of relaxation and adventure during their vacation.

  • Longtown: Nestled close to Perryville, Longtown is a charming village that offers a delightful escape for travelers seeking a romantic or culturally-themed experience. While the number of visitors remains somewhat steady throughout the year, the peak season from May to July attracts those eager to explore its historic landmarks. Longtown's quaint atmosphere is perfect for leisurely strolls, where you can soak in the local culture and enjoy small-town hospitality. Don’t miss out on the area's historical sites, which offer a glimpse into the past and add to the village's unique appeal.
  • Lithium: Just 8 miles from Perryville, the city of Lithium beckons with its vibrant entertainment and cultural scene. Like Longtown, its visitor numbers peak during the warmer months from May to July, making it an ideal spot for those looking for a mix of romance and fun. Lithium is home to several historic landmarks that provide insight into the region's rich heritage. Whether you're exploring the local arts or enjoying the city's lively atmosphere, you'll find that Lithium offers a dynamic travel experience that captivates and entertains.
  • Chester: Located 14 miles from Perryville, Chester is a haven for outdoor enthusiasts and adventure seekers. With its visitor peak from June to August, this city is known for its breathtaking scenery and recreational opportunities. Chester's proximity to lakes and national parks makes it perfect for hiking, fishing, and golfing. The local golf courses are a hit with both beginners and seasoned players alike. If you're looking for a place that combines natural beauty with thrilling activities, Chester is an excellent choice for an unforgettable getaway.

Things to do in and around Perryville

Perryville, Missouri, is perfect for outdoor and romantic getaways, offering a variety of scenic attractions. Enjoy recreational activities in the area's beautiful parks and take advantage of the local golf courses for a fun day on the greens. Explore nearby attractions to enhance your visit, making Perryville a delightful destination for nature lovers and adventure seekers alike.

Shopping

Perryville offers charming shopping experiences with local boutiques and gift shops downtown. If you're up for a drive, visit the Cape Girardeau Mall, about 15 miles away, featuring a wide range of retailers and dining options for a full day of shopping fun.

Recreation

At Perryville Country Club, enjoy a round of golf in a scenic outdoor setting that promotes relaxation and physical activity. For a serene experience, head to Pickle Springs Natural Area, where you can unwind amidst nature. Experience luxury and exclusivity at Sparta Country Club, perfect for a retreat.

Adventure

Perryville offers exciting outdoor adventures at the Perry County Park, where you can hike scenic trails and enjoy breathtaking views. For a thrilling experience, try the local zip-lining at Cape Girardeau, just a short drive away, and feel the rush as you soar through the trees.

Nightlife

Experience the lively atmosphere at The Landing, where you can enjoy great food and cocktails while soaking in the river views. For a more laid-back vibe, check out The Perryville Moose Lodge for friendly gatherings and occasional live music.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Perryville

Perryville, Missouri, provides several budget-friendly options for visitors. Enjoy free attractions like the National Shrine of Our Lady of the Miraculous Medal and take advantage of lower hotel rates from November to January, especially on Wednesdays. For transportation, consider using public buses or car rentals. To save further, utilize Expedia’s tools to find the best deals on hotel stays, flights, and activities, and join the One Key membership for exclusive discounts. Combining your bookings can lead to significant savings, ensuring a memorable yet affordable vacation in Perryville.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Perryville are November to January, where the prices are slightly lower. This is in comparison to April to May and July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Perryville is Wednesday. The most expensive day to stay in Perryville is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your preferences, including your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Perryville with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in Perryville

Perryville, Missouri, offers a charming blend of outdoor and romantic experiences, perfect for scenic getaways. Visitors can explore local shrines and memorials, as well as enjoy the serene beauty of nearby lakes. The area's attractions cater to those seeking cultural and family-oriented experiences, with a focus on historic sites. Don't miss the opportunity to discover Perryville's rich history through its various historic attractions, ensuring a memorable visit for all.

  • National Shrine of Our Lady of the Miraculous Medal: This serene shrine offers a peaceful atmosphere for reflection and prayer. Visitors can explore its beautiful gardens and captivating architecture, immersing themselves in its rich cultural significance and spiritual ambiance.
  • Missouri's National Veterans Memorial: A poignant tribute to those who served, this memorial provides a space for remembrance and honor. The striking design and informative displays create a deep appreciation for the sacrifices made by veterans, enhancing the cultural experience.
  • Saint Marys Lake: Embrace the natural beauty at this picturesque lake, offering a perfect spot for outdoor activities, romantic strolls, or simply relaxing on the beach. Enjoy stunning scenery and peaceful surroundings that make it an ideal getaway.

Best time to go to Perryville

The best time to visit Perryville can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Perryville falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Perryville falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January33.3°F (0.7°C)Light RainMostly SunnySlightly LowSlightly Low
February36.5°F (2.5°C)Light RainMostly SunnySlightly LowAverage
March47.3°F (8.5°C)Light RainMostly SunnyAverageAverage
April56.5°F (13.6°C)Light RainMostly SunnyAverageSlightly High
May66.4°F (19.1°C)Light RainMostly SunnySlightly HighSlightly High
June75.7°F (24.3°C)Light RainMostly SunnySlightly HighAverage
July78.6°F (25.9°C)Light RainMostly SunnySlightly HighSlightly High
August76.6°F (24.8°C)Light RainMostly SunnyAverageAverage
September70.5°F (21.4°C)Light RainMostly SunnyAverageAverage
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November46.4°F (8.0°C)Light RainMostly SunnyAverageSlightly Low
December38.8°F (3.8°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Perryville

When planning your trip to Perryville, Missouri, you have several airport options. The nearest is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), located 38 miles away, with nearby hotel options like Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both about 6 miles from the airport. Another choice is Marion, IL (MWA-Williamson County Regional), situated 47 miles from Perryville, where you can find accommodations such as Drury Inn & Suites Marion, just 2 miles away. Cairo, IL (CIR-Cairo Regional) is another option, located 58 miles away, with Quality Inn Cairo I-57 just 2 miles from the airport.

Frequently asked questions

What are the best hotels in Perryville that travelers recommend?
Urban Lofts in Perryville is a remarkable choice for travelers, boasting a stellar rating of 9.2. This hotel offers a blend of modern comfort and upscale amenities, featuring air conditioning, Egyptian cotton sheets, and premium bedding to ensure a restful night. Guests appreciate the attentive service that adds a touch of luxury to their stay, making it an ideal retreat for anyone seeking a relaxing getaway.
What are the top pet-friendly hotels in Perryville?
Urban Lofts in Perryville is an inviting pet-friendly hotel that guarantees a comfortable stay for both you and your furry companions. With a remarkable guest review rating of 9.2, this hotel stands out for its thoughtful amenities designed for travelers who appreciate quality service and convenience. See more pet-friendly hotels in Perryville.
What are the best budget hotels in Perryville?
Holiday Inn Express & Suites Perryville by IHG is a great choice for budget-conscious travelers seeking comfort and convenience. Rated 9.4 by guests, this hotel offers a delightful array of amenities, including a complimentary buffet breakfast to kick-start your day, free WiFi for staying connected, and an indoor pool superb for family fun. With 24-hour fitness facilities and accessible parking, it caters to both active and family-friendly visitors alike.

Another excellent option is Urban Lofts, which boasts a traveler review score of 9.2. This hotel offers a unique stay with family-friendly amenities like a kitchen for in-room dining and pet-friendly options, making it ideal for those traveling with furry friends. Guests appreciate the comfort of Egyptian cotton sheets and the convenience of free WiFi, ensuring a relaxed and enjoyable experience.

For those looking for more budget options, Super 8 by Wyndham Perryville provides an affordable stay with an indoor pool and free breakfast, rated 8.4 by travelers. This property welcomes families with its accessible parking and 24-hour fitness facilities, making it a practical choice for those seeking value.

If you're traveling as a couple or solo, Days Inn by Wyndham Perryville offers a cozy atmosphere with an outdoor seasonal pool and a business center for those needing to catch up on work. Quality Inn Perryville I-55 features an inviting outdoor pool and hot tub, superb for leisurely afternoons, making it a nice retreat for couples or travelers looking to unwind. View all budget hotels in Perryville.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Perryville.
How can I save on a Perryville hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Perryville hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Perryville hotel?
Prices for hotels in Perryville often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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