Find hotels in San Francisco, Panama City

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Our top choices for San Francisco hotels

Aloft Panama

3.5 star property
San Francisco
8.8 out of 10, Excellent, (890)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
$117 nightly
The price is $129
Dec 16 - Dec 17
Total with taxes and fees
Aloft Panama

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1002)
"Staff was very helpful. Great location."
United States
John
$114 nightly
The price is $125
Jan 3 - Jan 4, 2026
Total with taxes and fees
Courtyard by Marriott Panama Multiplaza Mall

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1103)
"Property and location was excellent. Staff is very accommodating and helpful. "
Canada
Helen
$119 nightly
The price is $131
Dec 24 - Dec 25
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (989)
"Was amazing food was delicious and stay was great "
United States
Amanda
$134 nightly
The price is $148
Jan 9 - Jan 10, 2026
Total with taxes and fees
Sheraton Grand Panama

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1261)
"Clean rooms, staff was amazing!!"
United States
Christopher
$122 nightly
The price is $135
Dec 12 - Dec 13
Total with taxes and fees
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2137)
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
$103 nightly
The price is $113
Dec 13 - Dec 14
Total with taxes and fees
Plaza Paitilla Inn Hotel

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1003)
"Wonderful stay!"
United States
Martha
$152 nightly
The price is $170
Dec 14 - Dec 15
Total with taxes and fees
Las Americas Golden Tower Panama

Boutique Apartments Panamá Coco del Mar

3.5 star property
San Francisco
7.4 out of 10, Good, (152)
"Clean room good place to stay "
United States
Gideon
$172 nightly
The price is $189
Dec 10 - Dec 11
Total with taxes and fees
Boutique Apartments Panamá Coco del Mar

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1007)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
$279 nightly
The price is $307
Dec 14 - Dec 15
Total with taxes and fees
JW Marriott Panama

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1435)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
$112 nightly
The price is $123
Dec 10 - Dec 11
Total with taxes and fees
Decapolis Hotel Panama City

Residence Inn by Marriott Panama City

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (535)
"Amazing hotel amazing view service great location perfect "
United States
Melissa
$161 nightly
The price is $177
Jan 2 - Jan 3, 2026
Total with taxes and fees
Residence Inn by Marriott Panama City

Boutique Apartments Atlapa

3.0 star property
San Francisco
8.0 out of 10, Very Good, (26)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
$129 nightly
The price is $141
Dec 14 - Dec 15
Total with taxes and fees
Boutique Apartments Atlapa

San Francisco by Wynwood House

3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
$174 nightly
The price is $189
Dec 10 - Dec 11
Total with taxes and fees
San Francisco by Wynwood House

Dovle Residences by HMS-Preferred Member

3.0 star property
San Francisco
$196 nightly
The price is $215
Dec 10 - Dec 11
Total with taxes and fees
Dovle Residences by HMS-Preferred Member

Casa Orquídea

2.0 star property
San Francisco
9.6 out of 10, Exceptional, (4)
"For me was very convenient "
United States
Natalia
$59 nightly
The price is $65
Dec 15 - Dec 16
Total with taxes and fees
Casa Orquídea

Wanders Panama by Boutique Apartments

4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
$299 nightly
The price is $329
Dec 14 - Dec 15
Total with taxes and fees
Wanders Panama by Boutique Apartments

Wanders & Yoo

4.0 star property
San Francisco
8.8 out of 10, Excellent, (9)
"Cool and modern condos, great location and views."
United States
Jorge
$302 nightly
The price is $333
Jan 5 - Jan 6, 2026
Total with taxes and fees
Wanders & Yoo

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
San Francisco
$141 nightly
The price is $155
Dec 13 - Dec 14
Total with taxes and fees
w Bright 1BR w Private Balcony in San Francisco

Living 73 Panamá by Boutique Apartments

3.0 star property
San Francisco
$160 nightly
The price is $193
Dec 22 - Dec 23
Total with taxes and fees
Living 73 Panamá by Boutique Apartments

Luxury 1BR Apt With Style

2.0 star property
San Francisco
$195 nightly
The price is $215
Dec 10 - Dec 11
Total with taxes and fees
Luxury 1BR Apt With Style
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
Learn more about San Francisco

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top San Francisco Hotel Reviews

Find out more about San Francisco

Top reasons to visit San Francisco

  • Stunning Ocean Views: Enjoy breathtaking views of the ocean and surrounding landscapes, perfect for photo opportunities.
  • Vibrant Nightlife: Experience an exciting nightlife scene with diverse entertainment options for all tastes.
  • Family-Friendly Activities: Explore a variety of attractions suitable for all ages, ensuring a fun-filled visit.
  • Cultural Immersion: Dive into the local culture and history by visiting nearby neighborhoods like Downtown San Rafael.
  • Diverse Accommodations: Choose from a range of lodging options, from luxury hotels to budget-friendly hostels.

Find great hotels in and around San Francisco

Explore the vibrant lodging options in San Francisco, Panamá, where you'll find a mix of hotels and hostels tailored to every traveler. Whether you're seeking a family-friendly retreat, a business-themed stay, or a budget-friendly backpacker experience, the area's accommodations cater to your needs. Discover the best hotels that combine comfort, convenience, and local charm, ensuring a memorable visit to this dynamic city.

  • Hotel Riu Plaza Panama: Located only a mile from San Francisco, Hotel Riu Plaza Panama is a 4-star eco-certified hotel that caters to adventurous and eco-conscious travelers. This property seamlessly blends business and leisure, making it an excellent choice for those seeking a dynamic vacation experience. With a range of amenities tailored for business travelers, including multiple meeting rooms, a well-equipped business center, and ample conference space, it offers everything you need for a productive stay. Additionally, guests can enjoy a variety of adventure sports and recreational activities both onsite and nearby, ensuring an exhilarating getaway.
  • Novotel Panama City: Nestled in the heart of Panama City, just a mile away from San Francisco, Novotel Panama City is a charming 4-star hotel perfect for families and couples alike. The hotel is designed with a city-themed ambiance, featuring amenities specifically for children, such as a shared playground and complimentary kids’ club. For couples, romance packages and limited-hours room service enhance the intimate atmosphere. With its central location, guests have easy access to local attractions, making it an ideal base for exploring the vibrant city while enjoying family-friendly and romantic experiences.
  • Plaza Paitilla Inn Hotel: Plaza Paitilla Inn Hotel, a 3.5-star property situated in San Francisco, offers a unique blend of business convenience and romantic ambiance. With business facilities including a 24-hour business center, conference center, and accessible meeting rooms, it’s well-suited for corporate travelers. Couples can indulge in romance packages and enjoy food and beverage services that create memorable dining experiences. The hotel also features an outdoor pool and spa services, including Swedish massages and body treatments, allowing guests to unwind and reconnect in a serene setting.

Where to stay near San Francisco

San Francisco, located in Panama City, offers a delightful blend of family-friendly activities and vibrant city life. Explore nearby neighborhoods like Downtown San Rafael for a taste of local culture and history. Whether you seek luxury or budget accommodations, San Francisco provides a welcoming atmosphere filled with friendly locals. Perfect for a weekend getaway, this area promises a mix of recreation and relaxation, ensuring a memorable travel experience.

  • Panama City: As the vibrant capital of Panama, Panama City is a bustling metropolis where modern skyscrapers meet rich history. Located in the heart of the city, San Francisco is surrounded by a variety of attractions that cater to all types of travelers. Visitors flock to Panama City for its family-friendly activities, dynamic business environment, and city-themed experiences. Highlights include shopping in expansive malls, enjoying local parks, and exploring nearby beaches. The city's unique blend of cultures and cuisines makes it a gastronomic delight, ensuring every meal is an adventure.
  • Obarrio: Situated just 0.9 miles from San Francisco, Obarrio is a chic neighborhood known for its upscale vibe. This area attracts visitors year-round, particularly during peak months like February and September. Obarrio is ideal for travelers looking for family-friendly activities and business-oriented venues. The neighborhood is dotted with trendy shopping areas and modern shopping centers, making it a retail paradise. Nearby, you can find inviting parks and beautiful streets perfect for leisurely strolls, adding to its appeal as a sophisticated urban destination.
  • Punta Pacifica: Located 1 mile from San Francisco, Punta Pacifica is an exclusive neighborhood known for its luxury residences and stunning ocean views. This area sees a consistent influx of travelers, especially during the summer months. Punta Pacifica is favored for its family-oriented attractions, business facilities, and city experiences. Visitors can explore stylish shopping centers and malls, while the proximity to beautiful beaches and parks invites relaxation and outdoor activities. The vibrant atmosphere and upscale amenities make Punta Pacifica a must-visit for anyone exploring Panama City.

Things to do in and around San Francisco

San Francisco is perfect for family vacations, business trips, and urban adventures. Visitors can enjoy stunning ocean views, explore vibrant shopping centers and malls, and unwind in picturesque picnic areas. The city's nightlife offers a lively experience, ensuring there's something for everyone to enjoy. Whether you're here for leisure or work, San Francisco provides a diverse array of activities to make your visit memorable.

Shopping

In San Francisco, visit Multiplaza Pacific Mall for a mix of entertainment and shopping. Multicentro Panama offers a vibrant family-friendly atmosphere, while Pacific Center is perfect for trendy finds. Each location provides a unique shopping experience with plenty of options for gifts and souvenirs.

Recreation

Estadio Rommel Fernandez offers an energetic atmosphere perfect for sports enthusiasts, while Estadio Nacional Rod Carew provides an exhilarating setting for various athletic events. Maracana Stadium, known for its vibrant sports culture, ensures a thrilling experience for visitors looking to immerse themselves in local sports vibes.

Adventure

Embark on the Honeycreeper Ridge Trail, a stunning hiking experience located 23 miles from San Francisco, where adventure meets breathtaking scenery. For a thrilling zipline experience, visit Gatun Eco Adventures, situated 29 miles away, and soar through the treetops surrounded by the beauty of nature.

Nightlife

Experience the vibrant nightlife in San Francisco by visiting the National Theater and Anita Villalaz Theater, both offering rich cultural performances just 3 miles away. For a closer option, check out Theater Circle, located only 1 mile away, perfect for family-friendly entertainment and romantic outings.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for San Francisco

When planning your trip to San Francisco, consider visiting between September and November for lower prices, especially on Tuesdays. Use Expedia to filter hotel options by budget and preferences, and consider booking a package for additional savings. Joining the One Key membership can provide exclusive discounts and allow you to earn rewards for future stays. For public transport, utilize Muni and BART for affordable travel around the city. Look for free activities like exploring Golden Gate Park and the waterfront at Fisherman’s Wharf to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around San Francisco are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around San Francisco is Tuesday. The most expensive day to stay around San Francisco is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to set your budget, choose your desired location, and customize various preferences. You can arrange the results to display prices from lowest to highest, making it easy to find the most affordable hotels right away. Additionally, you have the option to narrow down your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodations that you can book.
  • Consider bundling your trip: You can save money by combining your hotel stay in San Francisco with your flights and activities by booking an Expedia package.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near San Francisco

San Francisco is perfect for family, business, and city-themed vacations, offering a variety of attractions such as urban parks, street activities, and event venues. Visitors can immerse themselves in the vibrant culture and business experiences available in the city. Don’t miss the opportunity to explore local highlights, including the Santa Maria, ensuring a memorable stay in this dynamic destination.

  • Avenida Balboa: This bustling street offers stunning views of the ocean and the city skyline. A perfect spot to take a leisurely stroll, Avenida Balboa is lined with impressive skyscrapers, shops, and restaurants, immersing you in the vibrant urban vibe of Panama City.
  • Cinta Costera: A picturesque urban park that stretches along the coastline, Cinta Costera is ideal for families and outdoor enthusiasts. Enjoy walking, jogging, or biking while taking in the beautiful views of the water and the city, making it a perfect escape from the hustle and bustle.
  • Panama Viejo: This historic site is a UNESCO World Heritage site that showcases the remnants of the original Panama City. Explore fascinating ruins and learn about the rich culture and history of Panama, providing a captivating glimpse into the past.

Best time to go to San Francisco

The best time to visit San Francisco can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around San Francisco falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around San Francisco falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowAverage

The nearest major airports for your trip to San Francisco

Traveling to San Francisco is convenient with three major airports nearby. Tocumen International Airport (PTY) is located 10 miles away, with luxury options like JW Marriott Panama and The Santa Maria, both offering transportation services. Marcos A. Gelabert International Airport (PAC) is closer at 4 miles, featuring hotels such as Waldorf Astoria Panama and Hilton Panama, which provide various shuttle services. Lastly, Balboa Pacifico International Airport (BLB) is 8 miles away, with accommodations like Sofitel Legend Casco Viejo and Bristol Panama, also offering shuttle options. Each airport ensures easy access to your stay in the vibrant Panama City.

Frequently asked questions

What are the best family hotels in San Francisco?
Ramada Plaza By Wyndham Panama Punta Pacífica is an exceptional family-friendly option in Panama City, boasting a stellar review score of 9.6. This hotel shines with amenities tailored for families, including complimentary cribs and rollaway beds, ensuring comfort for all ages. The inviting pool area is superb for kids to splash around, while the child-friendly window design adds a layer of safety for younger guests.

For another delightful choice, the Plaza Paitilla Inn Hotel, rated 9.4 by travelers, offers cribs at no extra cost and a warm, inviting space that families appreciate. Guests can enjoy a hearty buffet breakfast and have easy access to daily housekeeping, making family stays convenient and stress-free.

If you're looking for more space, the Residence Inn by Marriott Panama City is a fantastic pick with a review score of 9.0. Its connecting rooms and comfortable sofa beds provide ample space for families, while the refreshing pool is ideal for fun-filled afternoons. Plus, the free weekday breakfast helps fuel the day's adventures.

For those seeking luxurious touches, the JW Marriott Panama, with a rating of 8.8, features connecting rooms and a pool suitable for all ages, ensuring a relaxing experience for families. Additionally, the option for free meals for children adds great value to your stay.

Lastly, the Courtyard by Marriott Panama Multiplaza Mall, also rated 8.8, is superb for families who appreciate convenience. With onsite babysitting services and a pool, parents can enjoy some downtime while the kids play. The provision of connecting rooms and flexible bedding options makes it a well-rounded choice for families seeking comfort and quality during their stay in Panama City.
What are the best 5-star hotels in San Francisco?
The JW Marriott Panama, a stunning 5-star hotel rated 8.8 by guests, offers an exceptional blend of luxury and convenience in the heart of Panama City. This premier destination boasts an outdoor pool complete with sun loungers and cabanas, great for basking in the sun while enjoying a refreshing drink from the poolside bar. With its stylish design and attentive service, the JW Marriott Panama ensures that every aspect of your stay is nothing short of extraordinary.
What are the best spa hotels in San Francisco?
In the bustling heart of Panama City, the Ramada Plaza By Wyndham Panama Punta Pacífica offers a delightful spa experience, boasting an exceptional score of 9.6. This hotel features treatment rooms that create a serene space for relaxation and rejuvenation, making it an excellent choice for travelers looking to unwind after a day of adventure.

For comprehensive wellness, the Plaza Paitilla Inn Hotel is another standout, rated 9.4 by guests. With a variety of spa services including hot stone massages, reflexology, and facial treatments, this hotel provides a holistic approach to relaxation. The on-site spa ensures you have all the amenities at your fingertips, allowing for a seamless wellness experience.

Another appealing option is the Las Americas Golden Tower Panama, which enjoys a rating of 8.8. This hotel features a full-service spa, accessible treatment rooms, and a sauna for an added touch of luxury. Guests appreciate the daily spa services that cater to diverse relaxation needs, enhancing the overall experience.

For those who enjoy a more personalized touch, the JW Marriott Panama also holds an 8.8 rating and offers in-room massage services. This feature allows guests to indulge in spa treatments in the comfort of their own space, making it a great choice for couples seeking a more intimate experience.

Lastly, the Decapolis Hotel Panama City, rated 8.6, is a fantastic option for spa enthusiasts. It offers an extensive range of services, from prenatal massages to Ayurvedic treatments, ensuring an extensive wellness journey. The hotel's focus on holistic health with amenities like a Turkish bath and steam room makes it especially appealing to those looking to relax deeply.
Which beach resorts in San Francisco do travelers love?
The Sheraton Grand Panama, a stunning resort in Panama City, is a favorite among travelers seeking a beachside escape. With an exceptional score of 8.6, guests appreciate the breathtaking ocean views that set the great backdrop for relaxation and adventure.
What hotels in San Francisco offer free breakfast?
Ramada Plaza By Wyndham Panama Punta Pacífica is a fantastic choice for travelers seeking family-friendly hotels in Panama City. With a customer review rating of 9.6, this hotel provides a inviting space that includes a complimentary breakfast buffet to kick-start your day. Families will appreciate the outdoor pool, where kids can splash around while parents relax on the sun loungers nearby. Additionally, the hotel's proximity to a shopping mall and various local attractions makes it convenient for family outings.

For another great option, consider the Residence Inn by Marriott Panama City, rated 9.0 by guests. This hotel also offers a delightful complimentary breakfast, ensuring everyone starts their day off right. The spacious suites are superb for families, providing room to spread out and feel at home. An outdoor pool invites fun and relaxation, while the 24-hour fitness center keeps parents active during their stay.

These properties are particularly well-suited for families, balancing adventure and convenience with quality amenities. If you're traveling as a couple, the Plaza Paitilla Inn Hotel, boasting a rating of 9.4, offers a more romantic setting with its onsite spa and outdoor pool, superb for unwinding after a day of exploring the vibrant city.
What are the best budget hotels in San Francisco?
For families seeking a budget-friendly stay in Panama City, ESHEL SUITES PANAMA is a standout option, boasting a great rating of 10.0. This hotel offers a wealth of amenities tailored to families, including free Wi-Fi, a kitchenette for those family meals, and stunning sea views that can make any stay feel special. The property also features a grocery shopping service, making it convenient for parents to stock up on snacks and essentials without the hassle.

Another excellent choice is the Plaza Paitilla Inn Hotel, which has earned a review score of 9.4. Families will appreciate the free breakfast, ensuring everyone starts the day off right. The outdoor pool is great for children to splash around, while parents can indulge in spa treatments, including massages and reflexology, for a little relaxation time. With self-parking options and a prime location, this hotel strikes a balance between comfort and convenience for travelers with kids.

For couples or solo travelers, properties like Aloft Panama, with a review rating of 8.6, may appeal. This hotel features a vibrant atmosphere, a pool with a poolside bar, and a fitness center for those looking to maintain their routine while away.

Whether traveling with family or on a romantic getaway, Panama City's hotels offer diverse options to meet your needs, ensuring a memorable stay filled with adventure and convenience.
What are the most romantic hotels in San Francisco for couples?
For couples seeking a romantic getaway in Panama City, the Ramada Plaza By Wyndham Panama Punta Pacífica is an exceptional choice, boasting a great rating of 9.6. This charming hotel features a delightful outdoor pool, great for a refreshing dip under the sun, along with a terrace that offers lovely views for a romantic evening. Guests can also enjoy premium bedding and the option for champagne service, creating an intimate atmosphere for couples.

Another wonderful option is the Plaza Paitilla Inn Hotel, rated 9.4 by guests. This hotel offers an extensive spa with a range of soothing treatments, including hot stone massages and facials, ideal for couples looking to unwind together. With outdoor pool access and complimentary breakfast, it ensures a convenient and enjoyable stay, allowing couples to focus on each other and their shared experiences.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right San Francisco hotel for you.
How can I save on a San Francisco hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible San Francisco hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a San Francisco hotel?
Hotel prices in San Francisco often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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