Santa Cruz Vacation Rentals

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Our top choices for Santa Cruz vacation rentals

Aparthotel in Santa Cruz

Equipetrol Suites Apart Hotel
2.5 star property
9.0 out of 10, Wonderful, (12 reviews)
"Perfect hotel"
Turkey
Yener
$49 nightly
The price is $49
Feb 26 - Feb 27
Equipetrol Suites Apart Hotel

Apartment in Santa Cruz

AMERICA APARTMENTS
3.0 star property
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
$55 nightly
The price is $55
Feb 25 - Feb 26
AMERICA APARTMENTS

Aparthotel in Santa Cruz

Terranova Suites
3.5 star property
8.0 out of 10, Very Good, (90 reviews)
"Easy to access"
United States
Dorothy
$48 nightly
The price is $48
Mar 3 - Mar 4
Terranova Suites
3.5 star property
9.0 out of 10, Wonderful, (86 reviews)
"Good price, great hotel!"
United States
James
$39 nightly
The price is $39
Feb 25 - Feb 26
Premium Suites Deluxe Aparthotel Equipetrol

Apartment in Santa Cruz de la Sierra

Lujo y confort en zona exclusiva
$55 nightly
The price is $55
Feb 25 - Feb 26
Lujo y confort en zona exclusiva
3.5 star property
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
$27 nightly
The price is $27
Feb 25 - Feb 26
Apart Hotel Premium Suites Santa Cruz

Apartment in Santa Cruz de la Sierra

Casa de 2 Habitaciones en zona norte
8.0 out of 10, Very Good, (1 review)
"Muy buen departamento, bien ubicado"
United States
Elva
$59 nightly
The price is $59
Feb 25 - Feb 26
Casa de 2 Habitaciones en zona norte

Aparthotel in Santa Cruz

Apart Hotel Toborochi
3.0 star property
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
Apart Hotel Toborochi

Apartment in Santa Cruz de la Sierra

Dppto Luminoso y Lujoso en Equipe Zona Empresarial
$65 nightly
The price is $65
Feb 25 - Feb 26
Dppto Luminoso y Lujoso en Equipe Zona Empresarial
$35 nightly
The price is $35
Feb 25 - Feb 26
Chalet indept, amplio, acogedor, hermoso jardin Aire C wifi, espa.xcocinar.
$83 nightly
The price is $83
Feb 25 - Feb 26
POX: 24th Floor Green Tower | Luxury and Panoramic View

Apartment in Santa Cruz de la Sierra

Apartamento confortable para 2 personas
$42 nightly
The price is $42
Feb 28 - Mar 1
Apartamento confortable para 2 personas
10.0 out of 10, Exceptional, (2 reviews)
"Zona tranquila y todo cerca supermercados tiendas etc"
Mexico
Fabricio O.
$60 nightly
The price is $60
Feb 25 - Feb 26
Tranquil apartment with WiFi in Santa Cruz de la Sierra

Apartment in Santa Cruz de la Sierra

Traveler's Hideout
10.0 out of 10, Exceptional, (1 review)
"The place was cozy, neat, and th host was very attentive and supportive. I recomend this place"
United States
Mauricio O.
$76 nightly
The price is $76
Feb 25 - Feb 26
Traveler's Hideout

Vacation Home in Santa Cruz de la Sierra

Cozy and independent.<br>Downtown house JH.
$52 nightly
The price is $52
Feb 25 - Feb 26
Cozy and independent.<br>Downtown house JH.
$67 nightly
The price is $67
Feb 25 - Feb 26
COMODO MONOAMBIENTE EN EQUIPETROL CON PISCINA EN CONDOMINIO!
$48 nightly
The price is $48
Feb 25 - Feb 26
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
$50 nightly
The price is $50
Feb 28 - Mar 1
Cozy 2-bedroom apartment with AC, WiFi in enjoyable Santa Cruz
$60 nightly
The price is $60
Feb 25 - Feb 26
Beautiful Loft in a brand new Condo, 10 minutes from business center.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $27 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we have vacation rentals in Santa Cruz near Santa Cruz Zoo, or you can go with a secluded option if you're looking for a relaxing stay. Discover why Santa Cruz is known for its shops. Make sure you have time to check out the cafes and zoo during your trip.

What are some of the best vacation home rentals in Santa Cruz?

Casa Vida: This highly rated vacation home rental in Santa Cruz is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other top choices in Santa Cruz are Jose Luis Noya and Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC.

How many vacation rentals will I find in Santa Cruz?

With 21 Expedia vacation rentals, you're sure to find just the right place for your Santa Cruz stay.

What can I see and do in Santa Cruz?

Enjoy the outdoors at Guembe Biocenter and Arenal Park, or simply take in cultural attractions like Cine Center and Ethno-folkloric Museum. Plaza 24 de Septiembre and Blacutt Square are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private accommodations you can stay in for several days or more in Santa Cruz. Vacation rentals provide amenities such as laundry facilities and kitchens so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family trip.