Search Guest Houses in Santee

Start date: Check-in selected.
To Date
End date: Check-out
  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Guest Houses in Santee

No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1002)
"Clean, friendly staff, new, good value"
United States
Robert
$121 nightly
The price is $134
Dec 14 - Dec 15
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

2.5 star property
Santee
9.6 out of 10, Exceptional, (1006)
"Rooms are clean, friendly staff and easy to get off and back on the highway. "
United States
Michelle
$112 nightly
The price is $124
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn Santee-I-95

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1407)
"The best stay"
United States
Terez
$75 nightly
The price is $83
Dec 8 - Dec 9
Total with taxes and fees
Baymont by Wyndham Santee

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (627)
"Nice place to stay"
Canada
Tanya
$95 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Tru By Hilton Santee

Best Western Plus Santee Inn

2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
$118 nightly
The price is $131
Dec 14 - Dec 15
Total with taxes and fees
Best Western Plus Santee Inn

Travelodge by Wyndham Santee

2.0 star property
Santee
7.0 out of 10, Good, (675)
"The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. "
United States
Alice
$61 nightly
The price is $68
Jan 5 - Jan 6, 2026
Total with taxes and fees
Travelodge by Wyndham Santee

Holiday Inn Santee by IHG

3.0 star property
Santee
8.2 out of 10, Very Good, (971)
"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
$127 nightly
The price is $141
Jan 5 - Jan 6, 2026
Total with taxes and fees
Holiday Inn Santee by IHG

Comfort Inn & Suites Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1000)
"Close to the highway with a safe location."
United States
Benjamin
$99 nightly
The price is $109
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites Santee

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee
10.0 out of 10, Exceptional, (37)
"Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! "
United States
Lauren B.
$288 nightly
The price is $320
Dec 8 - Dec 9
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Santee
10.0 out of 10, Exceptional, (11)
"Nice place great location "
United States
Jeffrey H.
$423 nightly
The price is $470
Dec 15 - Dec 16
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Super 8 by Wyndham Santee

2.0 star property
Santee
6.8 out of 10, (439)
"Clean room and felt safe and secured. "
United States
Kelly
$75 nightly
The price is $83
Dec 8 - Dec 9
Total with taxes and fees
Super 8 by Wyndham Santee

Tranquil Studio Cottage with Heated Pool and Fishing Access

Elloree
8.4 out of 10, Very Good, (6)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
$199 nightly
The price is $221
Jan 1 - Jan 2, 2026
Total with taxes and fees
Tranquil Studio Cottage with Heated Pool and Fishing Access

Econo Lodge

2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
$63 nightly
The price is $70
Dec 22 - Dec 23
Total with taxes and fees
Econo Lodge

Ramada by Wyndham Santee I-95

2.0 star property
Santee
6.2 out of 10, (541)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
$77 nightly
The price is $86
Jan 5 - Jan 6, 2026
Total with taxes and fees
Ramada by Wyndham Santee I-95

Quality Inn & Suites

2.5 star property
Santee
6.0 out of 10, (454)
"exellent service"
United States
Mirjana
$59 nightly
The price is $66
Dec 14 - Dec 15
Total with taxes and fees
Quality Inn & Suites

Fairfield Inn by Marriott Orangeburg

2.5 star property
Orangeburg
8.4 out of 10, Very Good, (685)
"Enjoyed my stay for homecoming go Bulldogs ! "
United States
David
$84 nightly
The price is $93
Dec 14 - Dec 15
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1005)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
$103 nightly
The price is $115
Dec 14 - Dec 15
Total with taxes and fees
Tru by Hilton Orangeburg

Best Inn of Manning

2.5 star property
Manning
7.4 out of 10, Good, (6)
"I was not pleased that I called after making reservation to request a room on the main level and was told that they would make a note and that this would be arranged but when I got there, they had me in an upstairs room. When I discussed this with the young lady at the front desk, she was kind and accomodating but I was put in a room then switched to another room. The bath tub faucet came out of the wall when I tried to pull up the tub plug. There was no waste basket in the room and the floor...
United States
rhonda
$68 nightly
The price is $76
Dec 14 - Dec 15
Total with taxes and fees
Best Inn of Manning

SureStay Hotel by Best Western Manning

2.5 star property
Manning
8.6 out of 10, Excellent, (1004)
"Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. "
United States
Monica
$89 nightly
The price is $99
Dec 8 - Dec 9
Total with taxes and fees
SureStay Hotel by Best Western Manning

Red Roof Inn St George, SC

2.5 star property
St. George
7.4 out of 10, Good, (633)
"Room was clean and the staff were good. Overall I would recommend this hotel!"
Canada
George
$66 nightly
The price is $73
Dec 14 - Dec 15
Total with taxes and fees
Red Roof Inn St George, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santee Hotel Reviews

Find out more about Santee

Santee Guest Houses information

Number of reviews
12,820
Accommodation
0 Guest Houses
Lowest Price
$66
Highest Price
$470

Explore a world of travel with Expedia