Florida Keys National Marine Sanctuary is the perfect place kick off your day in Key West. This protected ocean area is recommended by fellow travelers, but it isn't the only thing to do here. Pencil in time for other sights like Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens, and Mallory Square to make the most of what's on offer in the area.
Florida Keys National Marine Sanctuary Tours
Visit Florida Keys National Marine Sanctuary
Plan a trip to see Florida Keys National Marine Sanctuary
Price found within the past 48 hours. Click for updated prices.
Ella's Cottages - Key West Historic Inns
Old Town Key West
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Price was $1,270, price is now $736 per person
$736
per person
Jan 9 - Jan 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9.4/10 Exceptional! (378 reviews)
Loved it! Felt totally at home!!
Reviewed on Oct 30, 2025
The Key West Hotel
Key West Historic District
Save 100% on your flight
Price was $2,388, price is now $1,379 per person
$1,379
per person
Jan 9 - Jan 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9.2/10 Wonderful! (498 reviews)
Great location and friendly staff. They have remodeled a lot and are doing a super job. Nice decorations and LOVE the tiki bar and pool area. Key West Aloe products were a nice touch as well as the key lime cookies. The porch deck and handrail outside the Envy/Lust room needs a little attention. Overall, very comfortable and accommodating. I would definitely stay here again.
Reviewed on Oct 17, 2025
Winslow's Bungalows - Key West Historic Inns
Old Town Key West
Save 100% on your flight
Price was $1,323, price is now $779 per person
$779
per person
Jan 9 - Jan 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Key West (EYW)
9.2/10 Wonderful! (1,021 reviews)
Room was spotless, property beautiful, and Sonya at the reception is a rock star!! I look forward to my next visit.
Reviewed on Nov 1, 2025
Browse tours and tickets to explore Florida Keys National Marine Sanctuary
Tours & day trips
See all 120 activities
Miami to Key West Day Trip with Activity Options
Activity duration is 15 hours
8.4 out of 10 with 25 reviews
Free cancellation available
History & culture
See all 50 activities
Key West Conch Tour Train
Activity duration is 1 hour
8.8 out of 10 with 134 reviews
Free cancellation available
Private & custom tours
See all 27 activities
Dry Tortugas National Park Day Trip by Luxury Private Boat
Activity duration is 8 hours
Free cancellation available
Classes & workshops
See all 6 activities
Florida: Sunset Champagne Cruise on the Marathon Mermaid
Activity duration is 2 hours
Free cancellation available
Holiday & seasonal tours
See all 5 activities
The Dark Side of Key West Adults Only Walking Tour
Activity duration is 1 hour and 30 minutes
8.0 out of 10 with 3 reviews
Free cancellation available
Popular places to visit
Florida Keys Eco - Discovery Center
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
Fort Zachary Taylor Historic State Park
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
Truman Beach
Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
Jackson Square
You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
Harry S. Truman Little White House
Visit the winter home of President Harry S. Truman to see where some of America’s most important post-war decisions were made.
Key West Lighthouse and Keeper's Quarters Museum
Climb to the top of this historic lighthouse for unparalleled photo opportunities and then visit the former home of Key West’s lighthouse keepers.
Best Lodging Options Near Florida Keys National Marine Sanctuary
Check availability on hotels close to Florida Keys National Marine Sanctuary
Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
La Concha Key West, Autograph Collection
430 Duval St, Key West, FL
Pier House Resort & Spa
1 Duval St, Key West, FL
Casa Marina Key West, Curio Collection by Hilton
1500 Reynolds Street, Key West, FL
Hyatt Centric Key West Resort and Spa
601 Front St, Key West, FL
Opal Key Resort & Marina, Key West
245 Front Street, Key West, FL
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
Winslow's Bungalows - Key West Historic Inns
725 Truman Avenue, Key West, FL
Lighthouse Hotel - Key West Historic Inns
902 Whitehead St, Key West, FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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- Ernest Hemingway Home and Museum
- Fort Zachary Taylor Historic State Park
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- Florida Keys Eco - Discovery Center
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- Jackson Square
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- San Carlos Institute - Casa Cuba
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- Audubon House and Tropical Gardens
- Tennessee Williams Key West Exhibit
- Key West Museum of Art and History
- Roy John-Karl Gallery
- Red Barn Theater
- Curry Mansion Museum
- City Zoo Gallery
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- Donkey Milk House
- Mallory Dock
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