Title: Sepino Vacation Packages 2026 | Expedia.com [Sepino Travel Guide](https://expedia.com/Sepino.dx6129282)[Hotels in Sepino](https://expedia.com/Sepino-Hotels.d6129282.Travel-Guide-Hotels)[Vacation Rentals in Sepino](https://expedia.com/Sepino-Vacation-Rentals.d6129282.Travel-Guide-VacationRentals)[Flights to Sepino](https://expedia.com/Cheap-Flights-To-Sepino.d6129282.Travel-Guide-Flights)[Car Rentals in Sepino](https://expedia.com/Car-Rentals-In-Sepino.d6129282.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6129282/7ed35fdf-f64f-4545-a9cb-f472559da528.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Sepino Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Sepino Vacation Say goodbye to the worries of planning and hello to a Sepino vacation package. With the finer details organized before you leave, you can focus on discovering the best of this city, starting with Murat Town, which is good for views, shopping and walking. There's plenty to add to your must-see list during your trip to Sepino, beginning with top sights such as [Altilia Archaeological Site of Saepinum](https://www.expedia.com/Altilia-Archaeological-Site-Of-Saepinum-Sepino.d6321918.Vacation-Attraction) and [Porta Benevento](https://www.expedia.com/Porta-Benevento-Sepino.d553248621532499883.Vacation-Attraction). Stop daydreaming and start doing. Check out the many options on Expedia today and finally put your Sepino vacation plans into gear! ### Discover the most popular places to visit in Sepino #### Altilia Archaeological Site of Saepinum After visiting Altilia Archaeological Site of Saepinum, make a plan to see the other sights and activities in Sepino. You can enjoy the restaurants while in the area. [](https://expedia.com/Altilia-Archaeological-Site-Of-Saepinum-Sepino.d6321918.Vacation-Attraction) #### Porta Benevento Learn about the local history of Sepino with a stop at Porta Benevento. You can enjoy the restaurants while in the area. [](https://expedia.com/Porta-Benevento-Sepino.d553248621532499883.Vacation-Attraction) ### What to do in Sepino ![Excursion with clients](https://mediaim.expedia.com/localexpert/47575511/1fa96a57-0bbb-4c33-b341-d22ca58e5302.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Truffle Hunting with Food tasting $105 per adult [](https://expedia.com/things-to-do/truffle-hunting-with-food-tasting.a47575511.activity-details) ![Cantine D'Uva cellar](https://mediaim.expedia.com/localexpert/4294646/9c30ac97-6b06-4014-b0f4-9d6da6ebc01b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Private Tintilia del Molise Wine Tour from CAMPOBASSO $657 per adult [](https://expedia.com/things-to-do/private-tintilia-del-molise-wine-tour-from-campobasso.a4294646.activity-details) [See all activities in Sepino](https://expedia.com/things-to-do/search?rid=6129282) ## Sepino Hotel Deals ![Hotel Don Guglielmo](https://images.trvl-media.com/lodging/2000000/1840000/1839000/1838967/43f87a91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Don Guglielmo Contrada San Vito 15b Campobasso CB Fully refundableReserve now, pay when you stay 8.8/10 Excellent! (57 reviews) Yes Reviewed on Oct 26, 2025 [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=1838967&PinnedHotelID=1838967&HadPinnedHotel=true®ionId=6129282) [](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=1838967&PinnedHotelID=1838967&HadPinnedHotel=true®ionId=6129282) ![Centrum Palace](https://images.trvl-media.com/lodging/3000000/2700000/2692200/2692153/01243d35_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Centrum Palace Via Giambattista Vico 2/a Campobasso CB Fully refundableReserve now, pay when you stay $123 nightly $138 total Feb 8 - Feb 9 Total with taxes and fees 8.4/10 Very Good! (111 reviews) Clean room, dinning room excellent, beautiful decor, excellent staff Reviewed on Oct 29, 2025 [](https://expedia.com/Hotel-Search?startDate=2%2F8%2F2026&endDate=2%2F9%2F2026&selected=2692153&PinnedHotelID=2692153&HadPinnedHotel=true®ionId=6129282) ![Aquapetra Resort and Spa](https://images.trvl-media.com/lodging/2000000/1630000/1627900/1627826/5466a98c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aquapetra Resort and Spa S.S. Telesina, 1 Telese BN Fully refundableReserve now, pay when you stay 8.8/10 Excellent! (285 reviews) Beautiful design and space, fantastic staff. Reviewed on Sep 15, 2025 [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=1627826&PinnedHotelID=1627826&HadPinnedHotel=true®ionId=6129282) [](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=1627826&PinnedHotelID=1627826&HadPinnedHotel=true®ionId=6129282) [See all 297 properties in Sepino](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=6129282) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Sepino Vacation Packages ## Sepino Essential Information | Language | Italian | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Currency | Euros | | Local Welcome | Ciao | | Local Goodbye | Ciao | | Population | 930 | | Max Temp Winter | 50ºF | | Max Temp Summer | 80ºF | | Top Sights | [Porta Benevento](https://www.expedia.com/Porta-Benevento-Sepino.d553248621532499883.Vacation-Attraction) and [Altilia Archaeological Site of Saepinum](https://www.expedia.com/Altilia-Archaeological-Site-Of-Saepinum-Sepino.d6321918.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All 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[Campobasso Vacations ](https://www.expedia.com/Campobasso.d6056122.Destination-Travel-Guides) - [Visit Molise ](https://www.expedia.com/Molise.dx6048565) - [Cantine D'Uva ](https://www.expedia.com/Cantine-DUva-Murat-Town.d553248621532499881.Vacation-Attraction) - [Visit Province of Campobasso ](https://www.expedia.com/Province-Of-Campobasso.dx553248633194066979) - [Visit Campobasso ](https://www.expedia.com/Campobasso.dx6056122) - [Car rentals near Vinchiaturo ](https://www.expedia.com/Car-Rentals-In-Vinchiaturo.d6193193.Car-Rental-Guide) - [Car rentals near Bojano ](https://www.expedia.com/Car-Rentals-In-Bojano.d3000404548.Car-Rental-Guide) - [Luxury Car Rentals in Molise ](https://www.expedia.com/Luxury-Car-Rentals-In-Molise.d6048565-tLuxury.Car-Rental-Destination-Class) - [Car rentals near Molise ](https://www.expedia.com/Destinations-In-Molise.d6048565.Car-Rental-Destinations) - [Hertz Rental Cars in Molise 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