St. Charles Vacations from $383

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Your St. Charles Vacation

Spend less time planning and more time having fun adventures with a St. Charles vacation package. The neighborhood of Old Jamestown, which is great for nature and walking, makes a great base for your city escape. Fill your free time with tours of Ameristar Casino St. Charles, Hollywood Casino Amphitheatre and Historic Main Street, some of the top attractions you just have to see during a trip to St. Charles. A couple of clicks is all it takes to build your perfect St. Charles vacation on Expedia.

The Latest St. Charles vacation packages

Price found within the past 48 hours. Click for updated prices.
The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
Save 100% on your flight
Price was $543, price is now $383 per person
$383
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.4/10 Exceptional! (639 reviews)
Booked an extra night on the morning we were due to check out due to a cancelled flight. We were in town for a funeral. Got rebooked and checked out 2 hours later, without staying the extra night. We asked them to please refund due to the circumstances out of our control. They refused and insisted on collecting payment for a night of accommodations they did not provide. This may be technically allowed but it’s opportunistic and exploitative and not the kind of business I’m interested in patronizing.

Reviewed on Aug 1, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $794, price is now $404 per person
$404
per person
Sep 12 - Sep 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,668 reviews)
Everything was great. Staff was very helpful and friendly. I will definitely stay here next time I am in Missouri.

Reviewed on Aug 1, 2026

Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

2 out of 5
Save 100% on your flight
Price was $753, price is now $454 per person
$454
per person
Sep 3 - Sep 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
10/10 Exceptional! (1 review)
The property was excellent, and the home was very warm and welcoming.

Reviewed on Jun 25, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $616, price is now $394 per person
$394
per person
Oct 1 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,005 reviews)
Very charming property. We loved learning about a new author and the nice breakfast. Free street parking on the street is plentiful so I wouldn't pay for hotel parking. On-site restaurant was very loud and didn't have kid's menu but we made do.

Reviewed on Aug 1, 2026

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
Save 100% on your flight
Price was $565, price is now $404 per person
$404
per person
Sep 12 - Sep 17
found 2 days ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
Nice place

Reviewed on Aug 1, 2026

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Stay near popular St. Charles attractions

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Historic Main Street

9.4/10 (538 reviews)
Missouri's first state capital (1821-1826) features over 100 specialty shops along brick-paved streets. Explore historic buildings with elegant restaurants and boutiques while immersing yourself in 19th-century charm.
See properties

What to do in St. Charles

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

$175
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$25
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
See all activities in St. Charles

St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $195 total per night from Aug 3 to Aug 4
$195 total
Aug 3 - Aug 4
Total with taxes and fees
Ameristar Casino Resort and Spa
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Aug 30 to Aug 31
$112 total
Aug 30 - Aug 31
Total with taxes and fees
8/10 Very Good! (1,006 reviews)
"They got ys into our room after a horrible experience at another hotel promptly. We so kind and respectful. Will stay again."

Reviewed on Jul 31, 2026

Hampton Inn St. Charles St. Peters
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
$137 nightly
The price is $159 total per night from Aug 27 to Aug 28
$159 total
Aug 27 - Aug 28
Total with taxes and fees
Drury Plaza Hotel St. Louis St. Charles
See all 2,474 properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. Charles Vacation Packages

St. Charles Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
65,800
Max Temp Winter
40ºF
Max Temp Summer
85ºF
Top Sights
Chesterfield Sports Fusion, Kokomo Joes Family Fun Center and St. Louis Car Museum

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Frequently asked questions

How much does a St. Charles vacation package cost?
Offering great value package deals from $383 on Expedia, you'll be pleasantly surprised at how much a vacation to St. Charles costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to St. Charles?
June, July and December are the best times to look for cheap St. Charles vacation packages. Opting to travel in quieter periods means you can generally find better prices on hotels and flights.
How many days is enough for St. Charles?
St. Charles vacations come in various shapes and sizes, but to get a true feel for this destination, we'd suggest 2 days is about right. In this timeframe, you can fit in top attractions like Historic Main Street and Family Arena along with underrated gems. Don't miss out on cool neighborhoods such as St. Charles Historic District and Harvester either. If you're smart with your time, you may even be able to take a day trip or two from St. Charles too.
Is it worth booking a vacation package to St. Charles?
St. Charles has everything you need for a memorable getaway — festivals, nature and cycling are just the start. Whether you'd like to visit attractions such as Katy Trail and Lewis & Clark Boathouse and Nature Center, or take the road less traveled, you'll find plenty to experience on your St. Charles vacation.
How to find the best St. Charles package deals?
Use Expedia's filters to find some tempting St. Charles package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for St. Charles package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a St. Charles vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored St. Charles vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to St. Charles?
If you're considering an impromptu St. Charles trip, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find sensational deals on your hotels and flights by booking well in advance.
How to plan a trip to St. Charles?

  1. Choose when to go: Check your calendar and pack your bags. Your favorite time of year and the type of activities on offer will also help you decide when to visit St. Charles.
  2. Budget wisely: As well as the price of your stay, you should consider other expenses. These include food, flights and transportation. Also, put aside some extra funds for unexpected expenses that could crop up during your trip to St. Charles.
  3. Organize your St. Charles getaway with Expedia's trip planning tool: Search for and book stays and things to do all in one place. You can also collaborate with friends and family to plan an unforgettable trip to St. Charles together.
  4. Work out your trip length: Consider how much time you want to spend discovering St. Charles. Plan your itinerary so you can get to all the experiences and attractions you're interested in without rushing.
  5. Combine your airfare and accommodations: Once you've nailed down your dates and duration, lock in the right St. Charles vacation package for you.
  6. Add on excursions and experiences: Read our dedicated travel guide to find some awesome things to do in St. Charles in St. Charles. Book tickets or make reservations as soon as you can to save time and skip the hassle of trying to find activities when you arrive.

Does Expedia offer Book Now, Pay Later St. Charles vacation packages?
If you're like us, you love traveling but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your St. Charles trip over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.