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Find All Upstate South Carolina Hotels
We have found 2795 Upstate South Carolina Hotels
- Microtel Inn by Wyndham Duncan/Spartanburg
- Comfort Suites Greenville South
- Courtyard Greenville-Spartanburg by Marriott
- Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
- Days Inn by Wyndham Simpsonville
- Hampton Inn Greer Greenville, SC
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- Days Inn by Wyndham Clemson
- Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
- Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
- WoodSpring Suites Spartanburg - Duncan
- Staybridge Suites Greenville I-85 Woodruff Road by IHG
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Home2 Suites by Hilton Anderson Downtown
- Hampton Inn Anderson/ Alliance Business Park
- Hampton Inn Gaffney
- Days Inn by Wyndham Clinton / Laurens I-26
- Rodeway Inn Expo Center
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- Best Western Seneca-Clemson
- Comfort Suites Anderson-Clemson
- Hilton Garden Inn Spartanburg
- Hampton Inn Spartanburg-North I-85
- Quality Inn Clemson near University
- Hampton Inn Clemson-University Area
- Quality Inn Seneca Clemson Area US-123
- Swamp Rabbit Inn
- Holiday Inn Anderson by IHG
- Hometowne Studios Greenville
- Hampton Inn Greenville/Travelers Rest
- Quality Inn Duncan - Spartanburg West
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Comfort Suites Clinton near Presbyterian College
- Days Inn by Wyndham Seneca / Clemson Area
- Baymont by Wyndham Duncan/Spartanburg
- Inn on the Square, Ascend Hotel Collection
- Hampton Inn & Suites Clinton - I-26
- Red Roof Inn Greenville
- Hampton Inn Easley
- AC Hotel by Marriott Spartanburg
- Holiday Inn Spartanburg Northwest by IHG
- Country Inn & Suites by Radisson, Anderson, SC
- Quality Inn
- Quality Inn Clinton - Laurens I-26
- Candlewood Suites Greenville by IHG
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Residence Inn by Marriott Spartanburg
- Hampton Inn Simpsonville
- Red Roof Inn & Suites Greenwood, SC
- Home2 Suites by Hilton Greenville Airport
- Super 8 by Wyndham Anderson/Clemson Area
- Extended Stay America Select Suites Greenville Haywood Mall
- Home2 Suites by Hilton Duncan
- Courtyard Marriott Clemson
- Holiday Inn Express & Suites Greenwood Mall by IHG
- Comfort Inn & Suites Greenwood near University
- Red Roof Inn Spartanburg – I-26
- Fairfield Inn & Suites by Marriott Anderson Clemson
- Baymont by Wyndham Anderson Clemson
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Residence Inn by Marriott Spartanburg Westgate
- HomeTowne Studios by Red Roof Spartanburg - Asheville Highway
- Days Inn by Wyndham Spartanburg
- Hampton Inn Greenwood
- Quality Inn & Suites Easley - Greenville
- USA Economy Lodge
- Motel 6 Simpsonville, SC - Greenville
- Motel 6 Greenville, SC - I-85 Near Downtown
- Sleep Inn Gaffney at I-85
- Baymont by Wyndham Gaffney
- Hampton Inn Greenville/I-385 Haywood Mall
- Red Roof Inn Gaffney
- Swamp Rabbit Inn Travelers Rest
- Rodeway Inn
- Hampton Inn Anderson
- Super 8 by Wyndham Gaffney
- Homewood Suites by Hilton Greenville
- Red Roof Inn Spartanburg - I-85
- Red Roof Inn & Suites Duncan
- Tanglewood Inn
- Quality Inn Union US Hwy 176
- Super 8 by Wyndham Piedmont Greenville Area
- Fairfield Inn & Suites by Marriott Greenwood
- Quality Inn Greenwood Hwy 25
- Budget Inn Express
- Studio 6 Greenville, SC - I-85 Near Downtown
- Holiday Inn Express Anderson by IHG
- Quality Inn
- Residence Inn by Marriott Anderson Clemson
- Rodeway Inn
- Americas Best Value Inn Anderson, SC
- Econo Lodge
- Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
- Hotel Domestique
- Quality Inn Gaffney I-85
- The Bleckley Inn
- Suburban Studios Spartanburg - I-26
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.