--- title: "Lyon to Santander cheap flights from $67 (LYS to SDR) - Expedia" description: "Cheap Flights from Lyon (LYS) to Santander (SDR) start at $67 for one-way and $548 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/lys/sdr/lyon-to-santander" language: en-US market: US currency: USD prices_as_of: 2026-11-15T11:57:47Z --- # $67 Cheap Flights from Lyon (LYS) to Santander (SDR) ![A coastal cliff with a lighthouse and waves crashing against it.](https://images.trvl-media.com/place/3116/e8938b27-ae8d-4de2-8b9c-74bbcd502f67.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $67 flight on Tue, Dec 1, 2026](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:12/1/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:66.65&airProductToken=AQpsCjQI1rIBEgQ4MTI1GIuWASDBaCiz0Z4DMIjSngM4REAAWAFqCEZMWUxJR0hUcgdEQkFMQ1ZZCjQI1rIBEgQxMjA2GMFoIPKIASij054DMPPTngM4REAAWAFqCEZMWUxJR0hUcgdEQkFMQ1ZZEgoICxABGAgqAlZZGAEiBAgBEAEoAjAD) ## Popular airlines from Saint-Exupery Airport (LYS) to Santander (SDR) [Iberia](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:11/29/2026TANYT&leg2=from:SDR,to:LYS,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) [Vueling Airlines](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:11/29/2026TANYT&leg2=from:SDR,to:LYS,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"VY"}}]) ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Lyon to Santander (LYS-SDR) Prices were available within the past 7 days and start at $67 for one-way flights and $548 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $548 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:547.86&airProductToken=AQpoCjIIyYQBEgQxMTg2GIuWASCMGCj226UDMO7cpQM4TEAAWAFqBUJBU0lDcghMWk5OQTBCNAoyCMmEARIEMTA2NxiMGCDyiAEoquKlAzDw4qUDOExAAVgBagVCQVNJQ3IITFpOTkEwQjQKaAoyCMmEARIEMTA2OBjyiAEgjBgojuOlAzDU46UDOExAAFgBagVCQVNJQ3IITFpOTkEwQjQKMgjJhAESBDExNzkYjBggi5YBKPzopQMw7-mlAzhMQAFYAWoFQkFTSUNyCExaTk5BMEI0EgwIAhABGAIqAklCMgAYASIECAEQASgCKAMoBDAB) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $557 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:556.10&airProductToken=AQpoCjIIyYQBEgQxMTgwGIuWASCMGCjy3qUDMOrfpQM4TEAAWAFqBUJBU0lDcghMWk5OQTBCNAoyCMmEARIEMTA2NxiMGCDyiAEoquKlAzDw4qUDOExAAVgBagVCQVNJQ3IITFpOTkEwQjQKaAoyCMmEARIEMTA2OBjyiAEgjBgojuOlAzDU46UDOExAAFgBagVCQVNJQ3IITFpOTkEwQjQKMgjJhAESBDExODUYjBggi5YBKMfupQMwte-lAzhMQAFYAWoFQkFTSUNyCExaTk5BMEI0EgwIAhABGAIqAklCMgAYASIECAEQASgCKAMoBDAB) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $611 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:610.69&airProductToken=AQpoCjIIyYQBEgQxMTgwGIuWASCMGCjy3qUDMOrfpQM4TUAAWAFqBUJBU0lDcghNWk5OQTBCNAoyCMmEARIEMTA2MxiMGCDyiAEouuClAzCA4aUDOE1AAVgBagVCQVNJQ3IITVpOTkEwQjQKaAoyCMmEARIEMTA2OBjyiAEgjBgojuOlAzDU46UDOExAAFgBagVCQVNJQ3IITFpOTkEwQjQKMgjJhAESBDExNzkYjBggi5YBKPzopQMw7-mlAzhMQAFYAWoFQkFTSUNyCExaTk5BMEI0EgwIAhABGAIqAklCMgAYASIECAEQASgCKAMoBDAB) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $619 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:618.93&airProductToken=AQpoCjIIyYQBEgQxMTg2GIuWASCMGCj226UDMO7cpQM4TUAAWAFqBUJBU0lDcghNWk5OQTBCNAoyCMmEARIEMTA2MxiMGCDyiAEouuClAzCA4aUDOE1AAVgBagVCQVNJQ3IITVpOTkEwQjQKaAoyCMmEARIEMTA2OBjyiAEgjBgojuOlAzDU46UDOExAAFgBagVCQVNJQ3IITFpOTkEwQjQKMgjJhAESBDExODUYjBggi5YBKMfupQMwte-lAzhMQAFYAWoFQkFTSUNyCExaTk5BMEI0EgwIAhABGAIqAklCMgAYASIECAEQASgCKAMoBDAB) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $642 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:641.59&airProductToken=AQpqCjMIyYQBEgQxMTg2GIuWASCMGCj226UDMO7cpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDEwNjcYjBgg8ogBKKripQMw8OKlAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNApqCjMIyYQBEgQxMDY4GPKIASCMGCiO46UDMNTjpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDExNzkYjBggi5YBKPzopQMw7-mlAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNBIMCAIQARgCKgJJQjIAGAEiBAgBEAEoAigDKAQwAQ) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $650 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:649.83&airProductToken=AQpqCjMIyYQBEgQxMTgwGIuWASCMGCjy3qUDMOrfpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDEwNjcYjBgg8ogBKKripQMw8OKlAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNApqCjMIyYQBEgQxMDY4GPKIASCMGCiO46UDMNTjpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDExODUYjBggi5YBKMfupQMwte-lAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNBIMCAIQARgCKgJJQjIAGAEiBAgBEAEoAigDKAQwAQ) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $706 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:705.45&airProductToken=AQpqCjMIyYQBEgQxMTgwGIuWASCMGCjy3qUDMOrfpQM4TUAAWAFqBk9QVElNQXIITVpOTkEwTTQKMwjJhAESBDEwNjMYjBgg8ogBKLrgpQMwgOGlAzhNQAFYAWoGT1BUSU1BcghNWk5OQTBNNApqCjMIyYQBEgQxMDY4GPKIASCMGCiO46UDMNTjpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDExNzkYjBggi5YBKPzopQMw7-mlAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNBIMCAIQARgCKgJJQjIAGAEiBAgBEAEoAigDKAQwAQ) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $714 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:713.69&airProductToken=AQpqCjMIyYQBEgQxMTg2GIuWASCMGCj226UDMO7cpQM4TUAAWAFqBk9QVElNQXIITVpOTkEwTTQKMwjJhAESBDEwNjMYjBgg8ogBKLrgpQMwgOGlAzhNQAFYAWoGT1BUSU1BcghNWk5OQTBNNApqCjMIyYQBEgQxMDY4GPKIASCMGCiO46UDMNTjpQM4TEAAWAFqBk9QVElNQXIITFpOTkEwTTQKMwjJhAESBDExODUYjBggi5YBKMfupQMwte-lAzhMQAFYAWoGT1BUSU1BcghMWk5OQTBNNBIMCAIQARgCKgJJQjIAGAEiBAgBEAEoAigDKAQwAQ) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $773 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:772.40&airProductToken=AQpsCjQIyYQBEgQxMTg2GIuWASCMGCj226UDMO7cpQM4TEAAWAFqB0NPTUZPUlRyCExaTk5BMFU0CjQIyYQBEgQxMDY3GIwYIPKIASiq4qUDMPDipQM4TEABWAFqB0NPTUZPUlRyCExaTk5BMFU0CmwKNAjJhAESBDEwNjgY8ogBIIwYKI7jpQMw1OOlAzhMQABYAWoHQ09NRk9SVHIITFpOTkEwVTQKNAjJhAESBDExNzkYjBggi5YBKPzopQMw7-mlAzhMQAFYAWoHQ09NRk9SVHIITFpOTkEwVTQSDAgCEAEYAioCSUIyABgBIgQIARABKAIoAygEMAE) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip [Select Iberia flight, departing Sat, Feb 20 from Lyon to Santander, returning Sat, Feb 20, priced at $781 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:LYS,to:SDR,departure:2/20/2027TANYT&leg2=from:SDR,to:LYS,departure:2/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:780.64&airProductToken=AQpsCjQIyYQBEgQxMTgwGIuWASCMGCjy3qUDMOrfpQM4TEAAWAFqB0NPTUZPUlRyCExaTk5BMFU0CjQIyYQBEgQxMDY3GIwYIPKIASiq4qUDMPDipQM4TEABWAFqB0NPTUZPUlRyCExaTk5BMFU0CmwKNAjJhAESBDEwNjgY8ogBIIwYKI7jpQMw1OOlAzhMQABYAWoHQ09NRk9SVHIITFpOTkEwVTQKNAjJhAESBDExODUYjBggi5YBKMfupQMwte-lAzhMQAFYAWoHQ09NRk9SVHIITFpOTkEwVTQSDAgCEAEYAioCSUIyABgBIgQIARABKAIoAygEMAE) Sat, Feb 20 - Sat, Feb 20 · LYS · SDR · Roundtrip ## Book with confidence ### Lyon to Santander Flights #### The cheapest times to fly from Lyon to Santander On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lyon to Santander are during the month of February. You can find some of the cheapest flights from Lyon to Santander with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Lyon to Santander Sunday is one of the best days to book for cheap flights from Lyon to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Lyon to Santander Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lyon to Santander in 2026\. You can also book with separate airlines for your outbound and return journeys, from $67 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lyon to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Lyon to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Travel information | Origin airport | Saint-Exupery Airport | | ------------------- | ------------------------ | | Destination airport | Santander | | Distance | 465 miles away | | Airlines serving | Iberia, Vueling Airlines | | Popular airline | Iberia | | Roundtrip price | $548 | \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/ fr-FR: https://www.expedia.fr/lp/vols/lys/sdr/lyon-a-santander de-CH: https://www.expedia.ch/lp/fluege/lys/sdr/lyon-nach-santander ar: https://www.expedia.sa/lp/flights/lys/sdr/lyon-to-santander es: https://www.expedia.com/es/lp/vuelos/lys/sdr/lyon-a-santander es-ES: https://www.expedia.es/lp/vuelos/lys/sdr/lyon-a-santander ```