Cheap Flights from Chicago (MDW) to Muscle Shoals (MSL)

Popular airlines from Chicago Midway Airport (MDW) to Muscle Shoals, AL (MSL-Northwest Alabama Regional)

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL) cost?
Grab a cheap one-way flight or cheap return flight from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL)?
The cheapest month to fly from MDW to MSL is , when there's less demand. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from MDW to MSL. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL)?
You'll have to book a flight with a layover if you're traveling from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from MDW to MSL?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on a number of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL)?
Book a flight from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL) last-minute?
Booking your ticket from MDW to MSL right before your getaway is usually more expensive. However, if there's some wiggle room with your travel dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a MDW to MSL flight and hotel package?
You'll typically save money by booking a MDW to MSL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your preferred flights and accommodations, you can add extras such as activities, tours and car rentals.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to Northwest Alabama Regional Airport (MSL)?
Typically, you're able to reschedule or cancel your MDW to MSL flight. However, there may be additional charges, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like further details, go to our Customer Service portal.

Travel information

Origin airport
Midway Intl.
Destination airport
Northwest Alabama Regional
Distance
486 mi

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Chicago to Muscle Shoals Flights

The cheapest times to fly from Chicago to Muscle Shoals

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Muscle Shoals are during the month of . You can find some of the cheapest flights from Chicago to Muscle Shoals with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Muscle Shoals

Sunday is one of the best days to book for cheap flights from Chicago to Muscle Shoals: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Muscle Shoals

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Muscle Shoals in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Muscle Shoals flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Muscle Shoals airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to Muscle Shoals Flights

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*Available to One Key members.