$242 Cheap Flights from Pittsburgh (PIT) to Florence (FLO)

View $242 flight on Thu, Apr 30, 2026Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Pittsburgh to Florence (PIT-FLO)

Prices were available within the past 7 days and start at $242 for one-way flights and $416 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Apr 14 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$416 Roundtrip, found 3 days ago
$416
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Apr 14 from Pittsburgh to Florence, returning Sat, May 2, priced at $416 found 3 days ago
American Airlines
Sat, Mar 28 - Tue, Mar 31
PIT
Pittsburgh
FLO
Florence
$433 Roundtrip, found 17 hours ago
$433
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, Mar 28 from Pittsburgh to Florence, returning Tue, Mar 31, priced at $433 found 17 hours ago
American Airlines
Tue, Mar 17 - Tue, Mar 24
PIT
Pittsburgh
FLO
Florence
$437 Roundtrip, found 2 days ago
$437
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Mar 17 from Pittsburgh to Florence, returning Tue, Mar 24, priced at $437 found 2 days ago
American Airlines
Sat, Mar 21 - Tue, Mar 24
PIT
Pittsburgh
FLO
Florence
$446 Roundtrip, found 2 days ago
$446
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Mar 21 from Pittsburgh to Florence, returning Tue, Mar 24, priced at $446 found 2 days ago
American Airlines
Sat, Feb 21 - Wed, Mar 4
PIT
Pittsburgh
FLO
Florence
$447 Roundtrip, found 6 days ago
$447
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Feb 21 from Pittsburgh to Florence, returning Wed, Mar 4, priced at $447 found 6 days ago
American Airlines
Tue, Apr 14 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$448 Roundtrip, found 3 days ago
$448
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Apr 14 from Pittsburgh to Florence, returning Sat, May 2, priced at $448 found 3 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
PIT
Pittsburgh
FLO
Florence
$452 Roundtrip, found 1 hour ago
$452
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Apr 30 from Pittsburgh to Florence, returning Sat, May 9, priced at $452 found 1 hour ago
American Airlines
Tue, Mar 24 - Sun, Mar 29
PIT
Pittsburgh
FLO
Florence
$453 Roundtrip, found 2 days ago
$453
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Mar 24 from Pittsburgh to Florence, returning Sun, Mar 29, priced at $453 found 2 days ago
American Airlines
Tue, Mar 17 - Wed, Apr 1
PIT
Pittsburgh
FLO
Florence
$456 Roundtrip, found 1 day ago
$456
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 17 from Pittsburgh to Florence, returning Wed, Apr 1, priced at $456 found 1 day ago
American Airlines
Tue, Mar 3 - Mon, Mar 16
PIT
Pittsburgh
FLO
Florence
$457 Roundtrip, found 1 day ago
$457
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 3 from Pittsburgh to Florence, returning Mon, Mar 16, priced at $457 found 1 day ago

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Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $457
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $457

Frequently asked questions

How much does a flight from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) cost?
Get a cheap one-way flight from $242 or cheap return flight from $416 from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
Planning your getaway for April is a good way to save, as it's the cheapest month for flights between PIT and FLO. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
To find the cheapest airline that'll fly you from PIT to FLO, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
You'll need to book a flight with a layover when traveling from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from PIT to FLO?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
To reach Florence Regional Airport (FLO) on time, choose a flight that leaves from Pittsburgh Intl. Airport (PIT) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) last-minute?
Booking your plane ticket from PIT to FLO just before your trip is generally more expensive. However, if there's some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a PIT to FLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a PIT to FLO flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
In most instances, you can reschedule or cancel your PIT to FLO flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want more details, head to our Customer Service portal.

Travel information

Origin airport
Pittsburgh Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$416
Distance
436 mi

Book with confidence

Pittsburgh to Florence Flights

The cheapest times to fly from Pittsburgh to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pittsburgh to Florence are during the month of April. You can find some of the cheapest flights from Pittsburgh to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pittsburgh to Florence

Sunday is one of the best days to book for cheap flights from Pittsburgh to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pittsburgh to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pittsburgh to Florence in 2026. You can also book with separate airlines for your outbound and return journeys, from $242 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pittsburgh to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pittsburgh to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pittsburgh to Florence Flights

*Flight schedules are subject to change.

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