$237 Cheap Flights from San Antonio (SAT) to Panama City (PTY)

View $237 flight on Tue, Feb 10, 2026Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Tocumen Intl. Airport (PTY)

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Cheap Flights from San Antonio to Panama City (SAT-PTY)

Prices were available within the past 7 days and start at $237 for one-way flights and $500 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$500 Roundtrip, just found
$500
Roundtrip
just found
Select American Airlines flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $500 just found
Delta
Wed, May 20 - Wed, Jul 29
SAT
San Antonio
PTY
Panama City
$500 Roundtrip, found 1 hour ago
$500
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, May 20 from San Antonio to Panama City, returning Wed, Jul 29, priced at $500 found 1 hour ago
United
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$500 Roundtrip, just found
$500
Roundtrip
just found
Select United flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $500 just found
American Airlines
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$504 Roundtrip, just found
$504
Roundtrip
just found
Select American Airlines flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $504 just found
United
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$506 Roundtrip, just found
$506
Roundtrip
just found
Select United flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $506 just found
Delta
Sun, Jan 4 - Thu, Jan 22
SAT
San Antonio
PTY
Panama City
$509 Roundtrip, found 5 hours ago
$509
Roundtrip
found 5 hours ago
Select Delta flight, departing Sun, Jan 4 from San Antonio to Panama City, returning Thu, Jan 22, priced at $509 found 5 hours ago
United
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$511 Roundtrip, just found
$511
Roundtrip
just found
Select United flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $511 just found
American Airlines
Thu, Jan 15 - Tue, Jan 20
SAT
San Antonio
PTY
Panama City
$512 Roundtrip, found 9 hours ago
$512
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Thu, Jan 15 from San Antonio to Panama City, returning Tue, Jan 20, priced at $512 found 9 hours ago
United
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$513 Roundtrip, just found
$513
Roundtrip
just found
Select United flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $513 just found
Aeromexico
Tue, Feb 10 - Tue, Feb 24
SAT
San Antonio
PTY
Panama City
$703 Roundtrip, just found
$703
Roundtrip
just found
Select Aeromexico flight, departing Tue, Feb 10 from San Antonio to Panama City, returning Tue, Feb 24, priced at $703 just found

Find the cheapest month to fly from San Antonio (SAT) to Panama City (PTY)

April is typically the cheapest month to fly

From $445 - $1,031 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $570
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $570

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) cost?
Grab a cheap one-way flight from $237 or cheap return flight from $500 from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
Flying in February may help you find better deals, as it's the cheapest month for flights between SAT and PTY. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from SAT to PTY. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
You'll need to hop on a flight with a layover if you're traveling from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from SAT to PTY?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from SAT to PTY are typically more expensive. To secure the cheapest rates, start looking for flights as early as possible. That said, if your travel plans are flexible, you may score a cheap fare right before your journey.
Is it cheaper to book a SAT to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAT to PTY flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Simply secure your flights and choose from our extensive range of hotels, then personalize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Tocumen Intl. Airport (PTY)?
Generally, it's possible to reschedule or cancel your SAT to PTY flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
San Antonio Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Delta, United
Roundtrip price
$499
Distance
1877 mi

Book with confidence

San Antonio to Panama City Flights

The cheapest times to fly from San Antonio to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to Panama City are during the month of February. You can find some of the cheapest flights from San Antonio to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to Panama City

Sunday is one of the best days to book for cheap flights from San Antonio to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $237 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Antonio to Panama City Flights

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*Available to One Key members.