$123 Cheap American Airlines flights Charlotte (CLT) to Charleston (CHS)

Landing cheap one-way American Airlines flights from CLT to CHS from $123 on Expedia is simple — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $325 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months before your departure to score cheap fares on American Airlines flights from Charlotte-Douglas Intl. Airport (CLT) to Charleston Intl. Airport (CHS). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from CLT to CHS with American Airlines leaves at 7:25AM UTC-5. You'll land at 8:38AM UTC-5. The final American Airlines flight of the day leaves at 11:00PM UTC-5 and arrives at 12:04AM UTC-5. With around 20% fewer cancellations for early and mid-morning flights, heading out early is usually the best option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.