$153 Cheap American Airlines flights Charlotte (CLT) to Myrtle Beach (MYR)

Scoring cheap one-way American Airlines flights from CLT to MYR from $153 on Expedia is easy — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $281 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap American Airlines fares from Charlotte-Douglas Intl. Airport (CLT) to Myrtle Beach Intl. Airport (MYR), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the price you pay. Sunday is generally the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first flight from CLT to MYR with American Airlines leaves at 9:21AM UTC-5. You'll touch down at 10:40AM UTC-5. The last American Airlines flight of the day leaves at 10:45PM UTC-5 and arrives at 11:51PM UTC-5. With around 20% fewer cancellations for morning departures, heading out early is usually the best choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.