$80 Cheap American Airlines flights Colorado Springs (COS) to Myrtle Beach (MYR)

Make use of the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines round-trip flights from $164 from COS to MYR. Affordable one-way options from $80 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for cheap American Airlines flights from Colorado Springs Airport (COS) to Myrtle Beach Intl. Airport (MYR) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the best day of the week to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from COS to MYR with American Airlines, filter your search by "Morning" and "Early Morning." Choosing an early flight usually means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.