$271 Cheap American Airlines flights Sioux Falls (FSD) to San Antonio (SAT)

Landing cheap one-way American Airlines flights from FSD to SAT from $271 on Expedia is simple — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $205 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Sioux Falls Regional Airport (FSD) to San Antonio Intl. Airport (SAT) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to browse the earliest departures from FSD to SAT. Jetting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.