$149 Cheap Flights from Appleton (ATW) to Knoxville (TYS)

View $149 flight on Tue, Aug 25, 2026Opens in a new window

Popular airlines from Appleton, WI (ATW-Appleton Intl.) to McGhee Tyson Airport (TYS)

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Cheap Flights from Appleton to Knoxville (ATW-TYS)

Prices were available within the past 7 days and start at $149 for one-way flights and $291 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 26 - Sat, Aug 29
ATW
Appleton
TYS
Knoxville
$291 Roundtrip, found 2 days ago
$291
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Aug 26 from Appleton to Knoxville, returning Sat, Aug 29, priced at $291 found 2 days ago
United
Sat, Aug 8 - Sat, Aug 15
ATW
Appleton
TYS
Knoxville
$291 Roundtrip, found 18 hours ago
$291
Roundtrip
found 18 hours ago
Select United flight, departing Sat, Aug 8 from Appleton to Knoxville, returning Sat, Aug 15, priced at $291 found 18 hours ago
American Airlines
Sat, Jul 18 - Tue, Jul 21
ATW
Appleton
TYS
Knoxville
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jul 18 from Appleton to Knoxville, returning Tue, Jul 21, priced at $296 found 1 day ago
Delta
Tue, Jul 21 - Sun, Jul 26
ATW
Appleton
TYS
Knoxville
$300 Roundtrip, found 2 hours ago
$300
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Jul 21 from Appleton to Knoxville, returning Sun, Jul 26, priced at $300 found 2 hours ago
Delta
Wed, Sep 30 - Thu, Oct 8
ATW
Appleton
TYS
Knoxville
$305 Roundtrip, found 2 days ago
$305
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Sep 30 from Appleton to Knoxville, returning Thu, Oct 8, priced at $305 found 2 days ago
Delta
Fri, Aug 14 - Fri, Aug 21
ATW
Appleton
TYS
Knoxville
$309 Roundtrip, found 7 hours ago
$309
Roundtrip
found 7 hours ago
Select Delta flight, departing Fri, Aug 14 from Appleton to Knoxville, returning Fri, Aug 21, priced at $309 found 7 hours ago
Delta
Thu, Sep 10 - Mon, Sep 14
ATW
Appleton
TYS
Knoxville
$314 Roundtrip, found 8 hours ago
$314
Roundtrip
found 8 hours ago
Select Delta flight, departing Thu, Sep 10 from Appleton to Knoxville, returning Mon, Sep 14, priced at $314 found 8 hours ago
American Airlines
Tue, Aug 25 - Thu, Sep 3
ATW
Appleton
TYS
Knoxville
$318 Roundtrip, found 3 days ago
$318
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 25 from Appleton to Knoxville, returning Thu, Sep 3, priced at $318 found 3 days ago
United
Wed, Aug 5 - Sat, Aug 8
ATW
Appleton
TYS
Knoxville
$320 Roundtrip, found 20 hours ago
$320
Roundtrip
found 20 hours ago
Select United flight, departing Wed, Aug 5 from Appleton to Knoxville, returning Sat, Aug 8, priced at $320 found 20 hours ago
United
Tue, Nov 10 - Sat, Nov 14
ATW
Appleton
TYS
Knoxville
$322 Roundtrip, found 2 days ago
$322
Roundtrip
found 2 days ago
Select United flight, departing Tue, Nov 10 from Appleton to Knoxville, returning Sat, Nov 14, priced at $322 found 2 days ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $399
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $399

What you need to know for your flight from Appleton Intl. to McGhee Tyson

Appleton (ATW) to Knoxville (TYS) at a glance

Travel from Appleton (ATW) to Knoxville (TYS) with a range of airlines offering convenient domestic options. Compare flights from Appleton to Knoxville to find the itinerary that suits your budget and schedule as you plan your visit to the city's renowned attractions and neighborhoods. Discover essential details for flights departing from Appleton International Airport to McGhee Tyson Airport, ensuring a smooth journey to your destination.

  • Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 600 miles (970 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$410, depending on seasonality and how far ahead you book

Flights from Appleton International Airport (ATW) to McGhee Tyson Airport (TYS)

Based on recent traveler preferences, here are the top airlines flying from Appleton to Knoxville, known for their one-stop services. Common layovers include O'Hare International Airport (ORD) with an average layover of about 1 hour and 15 minutes, Hartsfield-Jackson Atlanta International Airport (ATL) also around 1 hour and 15 minutes, and Detroit Metropolitan Wayne County Airport (DTW) with a 1-hour layover. This variety allows you to balance price, travel time, and cabin class for the best travel experience.

  • Delta: This full-service airline provides one-stop options, featuring one-way ticket prices usually between $120 and $330. Delta represents about 35% of departures for this route, with a flight duration of 3 hours and 15 minutes, leading to an overall travel time of approximately 4 hours and 30 minutes, including layovers.
  • United: Another full-service option, United offers one-stop services with one-way fares typically ranging from $130 to $535. With around 34% of all departures on this route, passengers will experience an in-flight time of 3 hours and 15 minutes, culminating in a total journey duration of roughly 4 hours and 30 minutes, factoring in the layover.
  • American Airlines: As a full-service carrier, American Airlines features one-stop flights, with one-way fares generally between $120 and $460. This carrier handles about 32% of departures along this route, boasting an in-flight time of 3 hours and 15 minutes, and a complete travel time of around 4 hours and 30 minutes, including layover time.

Best time to fly from Appleton (ATW) to Knoxville (TYS)

The most popular months for travelers flying from Appleton to Knoxville are March, April, and July, when peak temperatures in Knoxville reach up to 77°F in July. If you prefer quieter travel, consider September, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 70.3°F. For better deals, May usually offers the lowest average one-way fare around $163. Flight availability peaks in July, with approximately 10 flights per week, making it easier to find convenient departure times. November and December have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: May usually offers good deals with average one-way fare around $163, roughly 30% cheaper than the yearly average.
  • Another budget-friendly time to fly: August typically offers an average one-way fare of around $173.
  • Most flight options: July has the highest number of flights from Appleton to Knoxville, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January37.8°F (3.2°C)Average8$217
February42.4°F (5.8°C)Average8$199
March49.5°F (9.7°C)High8$344
April57.6°F (14.2°C)High8$212
May66.4°F (19.1°C)Average9$163
June74.1°F (23.4°C)Average8$227
July77.0°F (25.0°C)High10$204
August75.7°F (24.3°C)Average9$173
September70.3°F (21.3°C)Low8$180
October59.5°F (15.3°C)Average8$335
November48.6°F (9.2°C)Low7$221
December43.0°F (6.1°C)Low7$328

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Appleton (ATW) to Knoxville (TYS)

  • Green Bay to Knoxville (GRB-TYS): Austin Straubel International Airport (GRB) is located approximately 25 miles from Appleton International Airport (ATW). One-way economy tickets for this journey generally fall within the range of $125 to $410, varying with the time of year and how far in advance you book. Flights on this route are commonly offered with one-stop options, featuring notable layovers at O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines servicing this route include United and Delta, with first-class service also available.

How to find the best prices for flights from Appleton (ATW) to Knoxville (TYS)

Getting some of the best deals on flights from Appleton to Knoxville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking at least two months in advance, although most travelers tend to book 2 to 8 weeks ahead. Afternoon departures from 12 PM to 6 PM typically offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Tuesday generally results in cheaper fares, though Friday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Knoxville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at McGhee Tyson Airport from Appleton International Airport

Knoxville welcomes travelers from Appleton with a range of transport options based on price, convenience, and proximity. Knoxville city center is approximately a 20-minute drive (covering about 15 miles) from McGhee Tyson Airport, depending on traffic. Here's how to reach Knoxville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Knoxville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from McGhee Tyson Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at McGhee Tyson Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) cost?
You can find cheap one-way flights from $149 and cheap return flights from $291 Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) with Expedia. One-way flights typically cost between $147 and $726, and return flights often range between $373 and $1181. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
January is the cheapest month to fly from Appleton, WI (ATW) to Knoxville, TN (TYS), with average round-trip fares around $313. This is about 28% lower than the average price throughout the year, as demand is typically lower during the winter months. Other affordable months to consider are February and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Enter ATW to TYS and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
To find a cheap flight from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The best times to fly from Appleton, WI (ATW) to Knoxville, TN (TYS) are January and September. You can find average return flight prices around $313 during these months, making them both economical and convenient for travelers. January offers a fresh start to the year, while September is great for enjoying the early fall scenery. This information is based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The earliest flight from Appleton, WI (ATW) to Knoxville, TN (TYS) typically leaves at around 5:00 AM local time, operated by American Airlines. This seasonal service is available in January, allowing you to arrive in Knoxville early and enjoy a full day at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The most popular departure times for flights from Appleton Intl. (ATW) to McGhee Tyson (TYS) are in the morning, from 6am to 9am. About 43% of passengers prefer this time window. Many major carriers, including American Airlines, United Airlines, and Delta, offer flights during this window. This timing is favored because it allows you to arrive in Knoxville with plenty of time to enjoy your day.
How long does it take to fly from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Flights from ATW to TYS with one stop typically take around 5 hours 50 minutes, covering approximately 631 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
First class seats are offered on the ATW to TYS route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight with Expedia?
It's easy to earn miles on a Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Knoxville from Appleton Intl. (ATW)?
If you're planning to travel to Knoxville from Appleton Intl. (ATW), you can fly into McGhee Tyson (TYS) Some flights may connect through major hubs like O'Hare Intl. (ORD), Detroit Metropolitan Wayne County (DTW), Minneapolis - St. Paul Intl. (MSP) before reaching Knoxville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) at the last minute?
Typically, booking a last minute flight from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package?
Securing a Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
If you booked your Appleton, WI (ATW-Appleton Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Appleton Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Roundtrip price
$290
Distance
630 mi

Book with confidence

Appleton to Knoxville Flights

The cheapest times to fly from Appleton to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Appleton to Knoxville are during the month of August. You can find some of the cheapest flights from Appleton to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Appleton to Knoxville

Sunday is one of the best days to book for cheap flights from Appleton to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Appleton to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Appleton to Knoxville in 2026. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Appleton to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Appleton to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Appleton to Knoxville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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