Cheap Flights from Buffalo (BUF) to Florence (FLO)

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Buffalo to Florence (BUF-FLO)

Prices were available within the past 7 days and start at for one-way flights and $447 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Dec 5 - Wed, Dec 31
BUF
Buffalo
FLO
Florence
$447 Roundtrip, found 5 days ago
$447
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Dec 5 from Buffalo to Florence, returning Wed, Dec 31, priced at $447 found 5 days ago
American Airlines
Mon, Nov 24 - Tue, Dec 9
BUF
Buffalo
FLO
Florence
$464 Roundtrip, found 3 days ago
$464
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 24 from Buffalo to Florence, returning Tue, Dec 9, priced at $464 found 3 days ago
American Airlines
Wed, Dec 3 - Sun, Dec 14
BUF
Buffalo
FLO
Florence
$467 Roundtrip, found 3 days ago
$467
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 3 from Buffalo to Florence, returning Sun, Dec 14, priced at $467 found 3 days ago
American Airlines
Tue, Dec 30 - Tue, Jan 13
BUF
Buffalo
FLO
Florence
$469 Roundtrip, found 3 days ago
$469
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Dec 30 from Buffalo to Florence, returning Tue, Jan 13, priced at $469 found 3 days ago
American Airlines
Wed, Dec 31 - Tue, Jan 13
BUF
Buffalo
FLO
Florence
$472 Roundtrip, found 3 days ago
$472
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 31 from Buffalo to Florence, returning Tue, Jan 13, priced at $472 found 3 days ago
American Airlines
Tue, Dec 30 - Sat, Jan 10
BUF
Buffalo
FLO
Florence
$474 Roundtrip, found 3 days ago
$474
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Dec 30 from Buffalo to Florence, returning Sat, Jan 10, priced at $474 found 3 days ago
American Airlines
Wed, Dec 31 - Sat, Jan 10
BUF
Buffalo
FLO
Florence
$477 Roundtrip, found 3 days ago
$477
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 31 from Buffalo to Florence, returning Sat, Jan 10, priced at $477 found 3 days ago
American Airlines
Mon, Nov 24 - Wed, Dec 10
BUF
Buffalo
FLO
Florence
$479 Roundtrip, found 3 days ago
$479
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 24 from Buffalo to Florence, returning Wed, Dec 10, priced at $479 found 3 days ago
American Airlines
Sun, Nov 23 - Tue, Dec 9
BUF
Buffalo
FLO
Florence
$481 Roundtrip, found 3 days ago
$481
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Nov 23 from Buffalo to Florence, returning Tue, Dec 9, priced at $481 found 3 days ago
American Airlines
Tue, May 19 - Sat, May 30
BUF
Buffalo
FLO
Florence
$483 Roundtrip, found 3 days ago
$483
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 19 from Buffalo to Florence, returning Sat, May 30, priced at $483 found 3 days ago
American Airlines
Tue, Apr 28 - Wed, May 13
BUF
Buffalo
FLO
Florence
$484 Roundtrip, found 3 days ago
$484
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Apr 28 from Buffalo to Florence, returning Wed, May 13, priced at $484 found 3 days ago
American Airlines
Wed, Apr 22 - Wed, May 13
BUF
Buffalo
FLO
Florence
$486 Roundtrip, found 3 days ago
$486
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Apr 22 from Buffalo to Florence, returning Wed, May 13, priced at $486 found 3 days ago
American Airlines
Mon, Apr 20 - Sat, May 2
BUF
Buffalo
FLO
Florence
$487 Roundtrip, found 3 days ago
$487
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Apr 20 from Buffalo to Florence, returning Sat, May 2, priced at $487 found 3 days ago
American Airlines
Fri, May 1 - Wed, May 20
BUF
Buffalo
FLO
Florence
$488 Roundtrip, found 3 days ago
$488
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 1 from Buffalo to Florence, returning Wed, May 20, priced at $488 found 3 days ago
American Airlines
Tue, May 19 - Wed, Jun 3
BUF
Buffalo
FLO
Florence
$488 Roundtrip, found 3 days ago
$488
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 19 from Buffalo to Florence, returning Wed, Jun 3, priced at $488 found 3 days ago
American Airlines
Wed, Apr 22 - Tue, May 12
BUF
Buffalo
FLO
Florence
$489 Roundtrip, found 3 days ago
$489
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Apr 22 from Buffalo to Florence, returning Tue, May 12, priced at $489 found 3 days ago
American Airlines
Wed, Dec 3 - Thu, Dec 18
BUF
Buffalo
FLO
Florence
$492 Roundtrip, found 3 days ago
$492
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Dec 3 from Buffalo to Florence, returning Thu, Dec 18, priced at $492 found 3 days ago
American Airlines
Sat, Nov 22 - Tue, Dec 9
BUF
Buffalo
FLO
Florence
$492 Roundtrip, found 3 days ago
$492
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 22 from Buffalo to Florence, returning Tue, Dec 9, priced at $492 found 3 days ago
American Airlines
Wed, May 13 - Wed, Jun 3
BUF
Buffalo
FLO
Florence
$493 Roundtrip, found 3 days ago
$493
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, May 13 from Buffalo to Florence, returning Wed, Jun 3, priced at $493 found 3 days ago
American Airlines
Sun, Nov 23 - Wed, Dec 10
BUF
Buffalo
FLO
Florence
$496 Roundtrip, found 3 days ago
$496
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Nov 23 from Buffalo to Florence, returning Wed, Dec 10, priced at $496 found 3 days ago

Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $492
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $492

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO) cost?
Grab a cheap one-way flight or cheap return flight from $447 from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO)?
Planning your trip for December is a good way to save, as it's the cheapest month for flights between BUF and FLO. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll fly you from BUF to FLO. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO)?
There are no daily nonstop flights from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from BUF to FLO?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO)?
To avoid possible delays on the Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO) last-minute?
Holding off until just before your departure to book a ticket from BUF to FLO generally means paying more. While you might find some last-minute discounts, there's no guarantee. Keep your travel schedule open to boost your chances of snagging a bargain.
Is it cheaper to book a BUF to FLO flight and hotel package?
You can save money by booking a BUF to FLO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After selecting your ideal accommodations and flights, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Florence Regional Airport (FLO)?
Typically, it's possible to reschedule or cancel your BUF to FLO flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$446
Distance
606 mi

Book with confidence

Buffalo to Florence Flights

The cheapest times to fly from Buffalo to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Florence are during the month of December. You can find some of the cheapest flights from Buffalo to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Florence

Sunday is one of the best days to book for cheap flights from Buffalo to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Florence in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Florence Flights

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*Available to One Key members.