A waterfall, a river, and ruins of an old structure.

$303 Cheap Flights from Buffalo (BUF) to Sioux Falls (FSD)

View $303 flight on Thu, Dec 3, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Sioux Falls Regional Airport (FSD)

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Cheap Flights from Buffalo to Sioux Falls (BUF-FSD)

Prices were available within the past 7 days and start at $303 for one-way flights and $311 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 12 - Sat, Aug 22
BUF
Buffalo
FSD
Sioux Falls
$311 Roundtrip, found 2 hours ago
$311
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Buffalo to Sioux Falls, returning Sat, Aug 22, priced at $311 found 2 hours ago
United
Wed, Aug 12 - Sat, Aug 22
BUF
Buffalo
FSD
Sioux Falls
$311 Roundtrip, found 2 hours ago
$311
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Aug 12 from Buffalo to Sioux Falls, returning Sat, Aug 22, priced at $311 found 2 hours ago
Delta
Thu, Sep 17 - Sat, Sep 19
BUF
Buffalo
FSD
Sioux Falls
$315 Roundtrip, just found
$315
Roundtrip
just found
Select Delta flight, departing Thu, Sep 17 from Buffalo to Sioux Falls, returning Sat, Sep 19, priced at $315 just found
Delta
Thu, Sep 17 - Sun, Sep 20
BUF
Buffalo
FSD
Sioux Falls
$319 Roundtrip, found 5 hours ago
$319
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Sep 17 from Buffalo to Sioux Falls, returning Sun, Sep 20, priced at $319 found 5 hours ago
United
Sat, Aug 29 - Mon, Aug 31
BUF
Buffalo
FSD
Sioux Falls
$330 Roundtrip, found 2 days ago
$330
Roundtrip
found 2 days ago
Select United flight, departing Sat, Aug 29 from Buffalo to Sioux Falls, returning Mon, Aug 31, priced at $330 found 2 days ago
Delta
Wed, Sep 16 - Sun, Sep 20
BUF
Buffalo
FSD
Sioux Falls
$340 Roundtrip, found 23 hours ago
$340
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Sep 16 from Buffalo to Sioux Falls, returning Sun, Sep 20, priced at $340 found 23 hours ago
Delta
Thu, Sep 17 - Sun, Sep 20
BUF
Buffalo
FSD
Sioux Falls
$344 Roundtrip, found 5 hours ago
$344
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Sep 17 from Buffalo to Sioux Falls, returning Sun, Sep 20, priced at $344 found 5 hours ago
United
Wed, Aug 5 - Tue, Aug 11
BUF
Buffalo
FSD
Sioux Falls
$357 Roundtrip, found 1 day ago
$357
Roundtrip
found 1 day ago
Select United flight, departing Wed, Aug 5 from Buffalo to Sioux Falls, returning Tue, Aug 11, priced at $357 found 1 day ago
United
Wed, Aug 5 - Tue, Aug 11
BUF
Buffalo
FSD
Sioux Falls
$364 Roundtrip, found 1 day ago
$364
Roundtrip
found 1 day ago
Select United flight, departing Wed, Aug 5 from Buffalo to Sioux Falls, returning Tue, Aug 11, priced at $364 found 1 day ago
United
Fri, Jul 24 - Mon, Jul 27
BUF
Buffalo
FSD
Sioux Falls
$365 Roundtrip, found 1 day ago
$365
Roundtrip
found 1 day ago
Select United flight, departing Fri, Jul 24 from Buffalo to Sioux Falls, returning Mon, Jul 27, priced at $365 found 1 day ago

What you need to know for your flight from Buffalo Niagara Intl. to Sioux Falls Regional

Buffalo (BUF) to Sioux Falls (FSD) at a glance

Travel between Buffalo (BUF) and Sioux Falls (FSD) with a range of airline options for this domestic short-haul route. Compare buffalo to sioux falls flights to discover the best choices that align with your budget, schedule, and travel plans as you set out to explore the iconic sights and neighborhoods of Sioux Falls. Gather all the essential details for your journey from Buffalo Niagara International Airport to Sioux Falls Regional Airport.

  • Fastest flight duration: around 3h 45m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 900 miles (1,450 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $130–$415, depending on seasonality and how far ahead you book

Flights from Buffalo Niagara International Airport (BUF) to Sioux Falls Regional Airport (FSD)

Based on the latest traveler bookings, here are the top airlines favored for journeys from Buffalo to Sioux Falls, typically offering one-stop services. Common layover points include O'Hare International Airport (ORD) with a layover of approximately 1 hour and 15 minutes, Dallas-Fort Worth International Airport (DFW) with a similar layover time, and Minneapolis-St. Paul International Airport (MSP), where the layover lasts about 2 hours. This variety allows you to balance price, total travel time, and cabin class for the best travel experience.

  • American Airlines: As a comprehensive service airline providing one-stop flights, American Airlines captures about 51% of departures on this route. One-way ticket prices generally fall between $130 and $410, with an in-flight duration of 3 hours and 45 minutes, resulting in a total travel time of roughly 5 hours, including a layover.
  • United: Another major player in the market, United operates one-stop services and makes up around 38% of the departures for this route. One-way fares typically range from $155 to $545, featuring an in-flight time of 3 hours and 45 minutes, leading to an overall journey time of approximately 5 hours, factoring in the layover.
  • Delta: Delta Airlines, offering one-stop service, accounts for about 11% of departures on this route. One-way fares usually vary from $180 to $375, with an in-air time of 3 hours and 45 minutes, culminating in a total journey duration of around 5 hours, including the layover.

Alternative route from Buffalo (BUF) to Sioux Falls (FSD)

  • Rochester to Sioux Falls (ROC-FSD): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy ticket prices for this journey generally fall between $130 and $740, varying according to the season and when the booking is made. This route is primarily served by one-stop flights, with common layover points at O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines operating on this route include United and American Airlines, and first-class service is also offered.

How to find the best prices for flights from Buffalo (BUF) to Sioux Falls (FSD)

Getting some of the best deals on flights from Buffalo to Sioux Falls is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking within two weeks, although most travelers tend to book 2-8 weeks in advance. Departures in the afternoon (12 PM-6 PM) often provide lower prices, while morning flights (5 AM-12 PM) are the most popular. Additionally, flying on Saturday generally results in cheaper fares, even though Friday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Sioux Falls hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Sioux Falls Regional Airport from Buffalo Niagara International Airport

Sioux Falls welcomes travelers from Buffalo with a range of transport options based on price, convenience, and proximity. Here's how to reach Sioux Falls efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Sioux Falls, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Sioux Falls Regional Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Sioux Falls Regional Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) cost?
You can find cheap one-way flights from $303 and cheap return flights from $311 Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) with Expedia. One-way flights typically cost between $208 and $753, and return flights often range between $416 and $1348. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The cheapest month to fly from BUF to FSD is August when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
Enter BUF to FSD and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Buffalo, NY (BUF) to Sioux Falls, SD (FSD), with round-trip tickets starting from around $281 with a layover in an unspecified location. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The earliest flight from Buffalo Niagara International Airport (BUF) to Sioux Falls Regional Airport (FSD) typically departs at around 5:05 AM, operated by American Airlines. This seasonal service is available in July, allowing you to kick off your day early in Sioux Falls. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The most popular departure times for flights from Buffalo, NY (BUF) to Sioux Falls, SD (FSD) are from 6am to 9am. About 37% of passengers prefer this time window. Many major carriers, including American Airlines and United, offer flights during this window. This timing is popular because it allows you to start your day early and arrive at your destination by midday.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
A flight from BUF to FSD with a layover takes around 4 hours 50 minutes, with the route covering approximately 905 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
First class seats are offered on the BUF to FSD route. First class cabins are available on:

  • Delta Air Lines
  • United Airlines
  • American Airlines

How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Sioux Falls from Buffalo Niagara Intl. (BUF)?
From Buffalo Niagara Intl. (BUF), you can fly into Sioux Falls Regional (FSD) to reach Sioux Falls. Some flights may connect through major hubs like Detroit Metropolitan Wayne County (DTW), Washington Dulles Intl. (IAD), LaGuardia (LGA) before reaching Sioux Falls. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) Sioux Falls Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Sioux Falls Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$310
Distance
905 mi

Book with confidence

Buffalo to Sioux Falls Flights

The cheapest times to fly from Buffalo to Sioux Falls

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Sioux Falls are during the month of August. You can find some of the cheapest flights from Buffalo to Sioux Falls with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Sioux Falls

Sunday is one of the best days to book for cheap flights from Buffalo to Sioux Falls: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Sioux Falls

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Sioux Falls in 2026. You can also book with separate airlines for your outbound and return journeys, from $303 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Sioux Falls flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Sioux Falls airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Sioux Falls Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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