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$180 Cheap Flights from Denver (DEN) to Greenville (GSP)

View $180 flight on Tue, Oct 20, 2026Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Denver to Greenville (DEN-GSP)

Prices were available within the past 7 days and start at $180 for one-way flights and $353 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Oct 30 - Sat, Oct 31
DEN
Denver
GSP
Greenville
$353 Roundtrip, found 3 hours ago
$353
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Oct 30 from Denver to Greenville, returning Sat, Oct 31, priced at $353 found 3 hours ago
Southwest Airlines
Wed, Oct 14 - Wed, Oct 21
DEN
Denver
GSP
Greenville
$359 Roundtrip, found 1 hour ago
$359
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Wed, Oct 14 from Denver to Greenville, returning Wed, Oct 21, priced at $359 found 1 hour ago
United
Wed, Nov 18 - Sun, Nov 22
DEN
Denver
GSP
Greenville
$359 Roundtrip, found 2 hours ago
$359
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Nov 18 from Denver to Greenville, returning Sun, Nov 22, priced at $359 found 2 hours ago
Southwest Airlines
Fri, Oct 16 - Sat, Oct 24
DEN
Denver
GSP
Greenville
$364 Roundtrip, found 1 hour ago
$364
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Fri, Oct 16 from Denver to Greenville, returning Sat, Oct 24, priced at $364 found 1 hour ago
United
Thu, Nov 19 - Sat, Nov 21
DEN
Denver
GSP
Greenville
$367 Roundtrip, found 5 days ago
$367
Roundtrip
found 5 days ago
Select United flight, departing Thu, Nov 19 from Denver to Greenville, returning Sat, Nov 21, priced at $367 found 5 days ago
United
Wed, Nov 18 - Sun, Nov 22
DEN
Denver
GSP
Greenville
$369 Roundtrip, found 2 hours ago
$369
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Nov 18 from Denver to Greenville, returning Sun, Nov 22, priced at $369 found 2 hours ago
Southwest Airlines
Mon, Nov 9 - Fri, Nov 13
DEN
Denver
GSP
Greenville
$370 Roundtrip, found 2 hours ago
$370
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Mon, Nov 9 from Denver to Greenville, returning Fri, Nov 13, priced at $370 found 2 hours ago
American Airlines
Fri, Oct 23 - Sat, Oct 24
DEN
Denver
GSP
Greenville
$373 Roundtrip, found 4 days ago
$373
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 23 from Denver to Greenville, returning Sat, Oct 24, priced at $373 found 4 days ago
United
Wed, Mar 24 - Wed, Mar 31
DEN
Denver
GSP
Greenville
$374 Roundtrip, found 3 hours ago
$374
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Mar 24 from Denver to Greenville, returning Wed, Mar 31, priced at $374 found 3 hours ago
Delta
Tue, Oct 20 - Mon, Oct 26
DEN
Denver
GSP
Greenville
$379 Roundtrip, just found
$379
Roundtrip
just found
Select Delta flight, departing Tue, Oct 20 from Denver to Greenville, returning Mon, Oct 26, priced at $379 just found

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $411
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $411

What you need to know for your flight from Denver Intl. to Greenville-Spartanburg Intl.

Denver (DEN) to Greenville (GSP) at a glance

Travel from Denver (DEN) to Greenville (GSP) with a selection of airlines providing convenient routes for this domestic short-haul journey. Explore your options with both full-service and budget-friendly carriers to discover the most affordable flights from Denver that align with your travel plans and schedule. Whether you're looking for the cheapest flights to Greenville or weekly flights from Denver, you can find essential information about flights from Denver International Airport to Greenville-Spartanburg International Airport.

  • Fastest flight duration: around 3 hours non-stop
  • Route distance: roughly 1,300 miles (2,090 km)
  • Flights per week: around 14 flights with multiple daily departures on average
  • Typical fares (one-way): economy tickets often range from $120–$470, depending on seasonality and how far ahead you book

Flights from Denver International Airport (DEN) to Greenville-Spartanburg International Airport (GSP)

Based on the latest traveler bookings, here are the top airlines flying from Denver to Greenville, favored for their one-stop and non-stop options. Common layover points include Charlotte-Douglas International Airport (CLT) with approximately a 1 hour and 30 minute wait, Hartsfield-Jackson Atlanta International Airport (ATL) with around a 1 hour and 15 minute layover, and Nashville International Airport (BNA) at about 55 minutes. This variety provides the flexibility to balance price, total travel time, and cabin class when planning your journey.

  • United: This full-service airline provides both non-stop and one-stop options, with one-way fares generally falling between $135 and $510. United accounts for about 35% of the departures on this route, featuring a standard non-stop flight duration of 3 hours.
  • American Airlines: Another full-service option, American Airlines offers one-stop flights, with one-way fares usually ranging from $120 to $425. Approximately 29% of the departures on this route are with American, featuring an in-flight duration of 4 hours and 15 minutes, leading to a total travel time of about 5 hours and 45 minutes, including layovers.
  • Southwest Airlines: This budget-friendly carrier provides both non-stop and one-stop services, with one-way fares typically between $120 and $335. Southwest accounts for around 18% of the departures on this route, with a standard 1-stop flight time of 4 hours and 15 minutes, resulting in a total journey time of roughly 5 hours and 45 minutes.
  • Delta: As a full-service airline, Delta offers one-stop services with one-way fares generally between $130 and $515. Delta represents about 18% of the departures on this route, with an in-flight duration of 4 hours and 15 minutes, leading to a total travel time of approximately 5 hours and 45 minutes, including any layovers.

Travelers have the option to enhance their journey from Denver to Greenville by upgrading to first class, with top airlines including United, American Airlines, and Delta offering premium service.

Best time to fly from Denver (DEN) to Greenville (GSP)

The most popular months for travelers flying from Denver to Greenville are March, April, and May, when peak temperatures in Greenville reach up to 68.4°F in May. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 61.9°F. For better deals, July usually offers the lowest average one-way fare around $219. Flight availability peaks in May, with approximately 21 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 11 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $219, roughly 13% cheaper than the yearly average.
  • More budget-friendly months to fly: August, April, and May typically offer average one-way fares roughly ranging from $221 to $238.
  • Most flight options: May has the highest number of flights from Denver to Greenville, with approximately 21 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January41.4°F (5.2°C)Average11$293
February45.3°F (7.4°C)Average12$260
March51.8°F (11.0°C)Slightly High14$293
April59.9°F (15.5°C)Slightly High14$231
May68.4°F (20.2°C)Slightly High21$238
June76.1°F (24.5°C)Average16$254
July79.5°F (26.4°C)Average17$219
August77.5°F (25.3°C)Average15$221
September72.3°F (22.4°C)Average15$238
October61.9°F (16.6°C)Slightly Low12$247
November51.1°F (10.6°C)Slightly Low13$280
December45.3°F (7.4°C)Slightly Low15$272

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Denver (DEN) to Greenville (GSP)

  • Colorado Springs to Greenville (COS-GSP): Located about 73 miles from Denver International Airport (DEN), Colorado Springs Airport (COS) offers a variety of travel options. One-way economy tickets on this route generally fall between $110 and $395, influenced by the time of year and when you book. Travelers can choose from one-stop and multi-stop flights, with frequent layovers at Dallas-Fort Worth International Airport (DFW) and Hartsfield-Jackson Atlanta International Airport (ATL). American Airlines and Delta are the leading airlines on this route, and first-class service is also available.

How to find the best prices for flights from Denver (DEN) to Greenville (GSP)

Getting some of the best deals on flights from Denver to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book 2 to 8 weeks ahead. Afternoon departures from 12 p.m. to 6 p.m. often provide lower prices, while morning flights from 5 a.m. to 12 p.m. are the most popular. Additionally, flying on Tuesday generally results in cheaper fares, while Friday is the most common travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Denver International Airport

Greenville welcomes travelers from Denver with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $180 and cheap return flights from $353 Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $219 and $790, and return flights often range between $378 and $1288. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The cheapest month to fly from DEN to GSP is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
You can fly direct from DEN to GSP on United, with around 9 flights per week.
How do I find cheap flights from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best airline to fly with from Denver, CO (DEN) to Greenville, SC (GSP) will differ from traveler to traveler. If you like to fly early, United offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. WN also offers the most daily flights from DEN to GSP, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
You can find approximately 1 nonstop flights per day from Denver Intl. (DEN) to Greenville-Spartanburg Intl. (GSP). For more options, look at flights that include layovers.
What is the earliest flight from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Denver, CO (DEN) to Greenville, SC (GSP) typically departs at around 12:15 AM, operated by American Airlines. This seasonal service runs in November and December, allowing you to arrive early and enjoy your time in Greenville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The most popular departure times for flights from Denver (DEN) to Greenville (GSP) are in the late morning, from 9am to noon. About 31% of passengers prefer this time window. Many major carriers, including United, American Airlines, and United, offer flights during this window. This timing is favored as it allows you to maximize your morning in Denver before your flight.
How long does it take to fly from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Flying nonstop from DEN to GSP takes around 3 hours 20 minutes, with the route covering approximately 1,276 miles. Flights with a layover typically take 4 hours 10 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
First class seats are offered on the DEN to GSP route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Denver Intl. (DEN)?
When traveling from Denver Intl. (DEN) to Greenville, you can fly into Mid Delta Regional (GLH), Greenville-Spartanburg Intl. (GSP) and Pitt-Greenville (PGV). Some flights may connect through major hubs like George Bush Intercontinental (IAH), San Diego Intl. (SAN), O'Hare Intl. (ORD) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Denver, CO (DEN-Denver Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Denver Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$353
Distance
1275 mi
Average flight time
3 hours 46 mins

Book with confidence

Denver to Greenville Flights

The cheapest times to fly from Denver to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Greenville are during the month of October. You can find some of the cheapest flights from Denver to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Greenville

Sunday is one of the best days to book for cheap flights from Denver to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $180 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Denver to Greenville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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