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$155 Cheap Flights from Greenville (GSP) to Milwaukee (MKE)

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to General Mitchell Intl. Airport (MKE)

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Cheap Flights from Greenville to Milwaukee (GSP-MKE)

Prices were available within the past 7 days and start at $155 for one-way flights and $273 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Delta
United
Delta
American Airlines
American Airlines
United
Delta
Southwest Airlines
United

Find the cheapest month to fly from Greenville (GSP) to Milwaukee (MKE)

October is typically the cheapest month to fly

From $250 - $374 per traveler.

What you need to know for your flight from Greenville-Spartanburg Intl. to General Mitchell Intl.

Greenville (GSP) to Milwaukee (MKE) at a glance

Travel from Greenville-Spartanburg International Airport (GSP) to General Mitchell International Airport (MKE) with a selection of airlines catering to this domestic short-haul route. You can search for Milwaukee flights that fit your budget and schedule, whether you’re looking for a cheap ticket from Greenville or a more comprehensive service. Discover the key details for flights from Greenville to Milwaukee as you plan your visit to explore the city’s renowned attractions and neighborhoods.

  • Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 30m layover with one stop
  • Route distance: roughly 600 miles (970 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$365, depending on seasonality and how far ahead you book

Flights from Greenville-Spartanburg International Airport (GSP) to General Mitchell International Airport (MKE)

Based on recent traveler bookings, here are the top airlines favored for one-stop flights from Greenville to Milwaukee. Popular layover options include Hartsfield-Jackson Atlanta International Airport (ATL, approximately 1h 30m), O'Hare International Airport (ORD, around 1h 30m), and Charlotte-Douglas International Airport (CLT, about 1h 15m). These choices allow you to mix and match pricing, total travel time, and cabin class to craft the best itinerary for your journey.

  • Delta: As a comprehensive service airline, Delta provides one-stop flights with one-way ticket prices generally falling between $125 and $370. This carrier represents about 52% of the departures on this route, featuring an in-flight duration of 3 hours and 15 minutes, with a total travel time of around 4 hours and 30 minutes, including layover.
  • American Airlines: Offering a full-service experience, American Airlines has one-stop flights with one-way fares usually ranging from $125 to $345. It accounts for approximately 29% of the departures on this route and has a flight time of 3 hours and 15 minutes, resulting in an overall journey time of about 4 hours and 30 minutes, including layover.
  • United: United Airlines is another full-service option, providing one-stop flights with one-way fares that typically range from $145 to $375. This airline makes up about 13% of the departures on this route, with an in-flight duration of 3 hours and 15 minutes and a total travel time of approximately 4 hours and 30 minutes, including layover.
  • Southwest Airlines: Known for its budget-friendly service, Southwest Airlines offers one-stop flights with one-way fares usually between $125 and $365. It holds about 6% of the departures on this route, featuring a flight time of 3 hours and 15 minutes, with a complete journey time of roughly 4 hours and 30 minutes, including layover.

Travelers flying from Greenville to Milwaukee have the option to upgrade their flight, with Delta providing first-class service on this route.

Best time to fly from Greenville (GSP) to Milwaukee (MKE)

The most popular months for travelers flying from Greenville to Milwaukee are March, April, and October, when peak temperatures in Milwaukee reach up to 52°F in October. If you prefer quieter travel, consider July, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 71.4°F. For better deals, May usually offers the lowest average one-way fare around $184. Flight availability peaks in September, with approximately 14 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: May usually offers good deals with average one-way fare around $184, roughly 14% cheaper than the yearly average.
  • More budget-friendly months to fly: December and July typically offer average one-way fares roughly ranging from $189 to $201.
  • Most flight options: September has the highest number of flights from Greenville to Milwaukee, with approximately 14 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January22.1°F (-5.5°C)Average7$223
February23.5°F (-4.7°C)Moderately Low8$232
March34.7°F (1.5°C)Moderately High10$241
April43.7°F (6.5°C)Moderately High10$241
May54.9°F (12.7°C)Average11$184
June64.9°F (18.3°C)Moderately Low9$213
July71.4°F (21.9°C)Moderately Low11$201
August70.7°F (21.5°C)Average10$209
September64.2°F (17.9°C)Average14$211
October52.0°F (11.1°C)Moderately High13$211
November39.2°F (4.0°C)Average11$231
December29.7°F (-1.3°C)Average10$189

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Greenville (GSP) to Milwaukee (MKE)

  • Greenville to Milwaukee (GDC-MKE): Donaldson Center Airport (GDC) lies approximately 13 miles from Greenville-Spartanburg International Airport (GSP).
  • Spartanburg to Milwaukee (SPA-MKE): Spartanburg Downtown Memorial Airport (SPA) is located around 15 miles from Greenville-Spartanburg International Airport (GSP).
  • Greenville to Kenosha (GSP-ENW): Kenosha Regional Airport (ENW) is about 24 miles from General Mitchell International Airport (MKE).

How to find the best prices for flights from Greenville (GSP) to Milwaukee (MKE)

Getting some of the best deals on flights from Greenville to Milwaukee is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are often found when booking at least two months in advance, although most travelers usually book between two to eight weeks ahead. Afternoon departures from 12 PM to 6 PM tend to be less expensive, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Monday generally offers lower prices, despite Thursday being the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at General Mitchell International Airport from Greenville-Spartanburg International Airport

Milwaukee welcomes travelers from Greenville with a range of transport options based on price, convenience, and proximity. For departures, Greenville-Spartanburg International Airport is roughly a 20-minute drive (covering about 16 miles) from central Greenville. Here's how to reach Milwaukee efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Milwaukee, with private rides that can be arranged in advance.
  • Car rental: Renting a car from General Mitchell International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at General Mitchell International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From General Mitchell International Airport, Milwaukee Airport Bus Station (a bus station) is located just 0.1 miles away on foot, while Milwaukee Airport Station (a train station) is about 1.8 miles from the airport and accessible by car. Additionally, Michigan & Jackson Tram Stop (a metro station) is situated approximately 7.8 miles away by car.

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) cost?
You can find cheap one-way flights from $155 and cheap return flights from $273 Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) with Expedia. One-way flights generally range between $150 and $563, and roundtrip flights usually range from $322 to $1034. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
May is the cheapest month to fly from Greenville to Milwaukee, with average return fares around $322. This price is about 16% lower than the average for the year, as travel demand tends to be lower in late spring. Other budget-friendly months to consider are January and March.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
Enter GSP to MKE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Greenville, SC (GSP) to Milwaukee, WI (MKE), with round-trip tickets starting from around $191. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
For flights from Greenville (GSP) to Milwaukee (MKE), May and January are the best months to fly. You can find return flights at around $322 in May, which is a great deal. While August and September are popular months, they can be busier. By flying in May or January, you can enjoy lower prices and a more relaxed travel experience, based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
The earliest flight from Greenville-Spartanburg International (GSP) to General Mitchell International (MKE) usually departs at around 5:00 AM, operated by American Airlines. This early departure can help you maximize your day in Milwaukee. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
The most popular departure times for flights from Greenville-Spartanburg Intl. (GSP) to Milwaukee (MKE) are in the early morning, from 6am to 9am. About 30% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United offer flights during this window. This timing works well because it allows you to start your day early and arrive in Milwaukee with plenty of time to explore.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
A flight from GSP to MKE with a layover takes around 6 hours, with the route covering approximately 635 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
First class seats are offered on the GSP to MKE route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Milwaukee from Greenville-Spartanburg Intl. (GSP)?
If you're planning to travel to Milwaukee from Greenville-Spartanburg Intl. (GSP), you can fly into General Mitchell Intl. (MKE) Some flights may connect through major hubs like Washington Dulles Intl. (IAD), Liberty Intl. (EWR), Baltimore Washington Intl. Thurgood Marshall (BWI) before reaching Milwaukee. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) Milwaukee Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Milwaukee, WI (MKE-General Mitchell Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
General Mitchell Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$273
Distance
634 mi

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