---
title: "Islip to Des Moines cheap flights from $234 (ISP to DSM) - Expedia"
description: "Cheap Flights from Islip (ISP) to Des Moines (DSM) start at $234 for one-way and $467 for round trip. Earn your airline miles on top of our rewards!"
canonical: "https://www.expedia.com/lp/flights/isp/dsm/islip-to-des-moines"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-14T03:02:35Z
---

# $234 Cheap Flights from Islip (ISP) to Des Moines (DSM)
![A modern building with a glass dome, surrounded by lush gardens and a clear blue sky with clouds.](https://images.trvl-media.com/place/5067588/3bf608f3-3ae2-4739-849f-181b3fe5cb60.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

[View $234 flight on Fri, Feb 5, 2027](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:233.50&airProductToken=AQqPAQouCNecARIEMTI2MhjIfCDzAyi8t6QDMPW4pAM4SkAAWAFqA1dHQXIHSlhBVlMyRwotCNecARIDNDQ5GPMDIINpKN65pAMw3bukAzhKQAFYAWoDV0dBcgdKWEFWUzJHCi4I15wBEgQyOTI2GINpIMNkKPi8pAMw4b2kAzhKQAFYAWoDV0dBcgdKWEFWUzJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ)

## Popular airlines from MacArthur Airport (ISP) to Des Moines International Airport (DSM)

[American Airlines](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}])

[United](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}])

[Southwest Airlines](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}])

[Delta](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}])

[Frontier Airlines](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}])

[JetBlue Airways](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}])

[Alaska Airlines](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:11/28/2026TANYT&leg2=from:DSM,to:ISP,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}])

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## Cheap Flights from Islip to Des Moines (ISP-DSM)

Prices were available within the past 7 days and start at $234 for one-way flights and $467 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $467 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:467.00&airProductToken=AQqPAQouCNecARIEMTI2MhjIfCDzAyi8t6QDMPW4pAM4SkAAWAFqA1dHQXIHSlhBVlMyRwotCNecARIDNDQ5GPMDIINpKN65pAMw3bukAzhKQAFYAWoDV0dBcgdKWEFWUzJHCi4I15wBEgQyOTI2GINpIMNkKPi8pAMw4b2kAzhKQAFYAWoDV0dBcgdKWEFWUzJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $473 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:472.30&airProductToken=AQqPAQouCNecARIEMTI2MhjIfCDzAyi8t6QDMPW4pAM4SkAAWAFqA1dHQXIHSlhBVlMyRwotCNecARIDNDQ5GPMDIINpKN65pAMw3bukAzhKQAFYAWoDV0dBcgdKWEFWUzJHCi4I15wBEgQyOTI2GINpIMNkKPi8pAMw4b2kAzhKQAFYAWoDV0dBcgdKWEFWUzJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Jan 8 from Islip to Des Moines, returning Mon, Jan 11, priced at $478 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:1/8/2027TANYT&leg2=from:DSM,to:ISP,departure:1/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:477.60&airProductToken=AQqRAQotCNecARIDMjI2GMh8IMFFKPr9oQMwyv6hAzhKQABYAWoDV0dBcgdKWEFWUzJHCi8I15wBEgQ0MDIxGMFFIOywASiz%5F6EDMKOBogM4SkABWAFqA1dHQXIHSlhBVlMyRwovCNecARIENDEwNhjssAEgw2QogoKiAzDXgqIDOEpAAVgBagNXR0FyB0pYQVZTMkcSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB)

Fri, Jan 8 - Mon, Jan 11 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $482 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:482.00&airProductToken=AQqQAQouCNecARIEMTk5MRjIfCDBRSihu6QDMPG7pAM4SkAAWAFqA1dHQXIHSlhBVlMyRwouCNecARIDMjk0GMFFIIuQASiqvaQDMO-%5FpAM4SkABWAFqA1dHQXIHSlhBVlMyRwouCNecARIDODI0GIuQASDDZCinw6QDMNbEpAM4SkABWAFqA1dHQXIHSlhBVlMyRwqQAQouCNecARIEMTc2MRjDZCChAyjq2KQDMNPZpAM4QUAAWAFqA1dHQXIHQUxBV1YyRwotCNecARICOTAYoQMgo5oBKPrbpAMwgd2kAzhBQAFYAWoDV0dBcgdBTEFXVjJHCi8I15wBEgQzMzU0GKOaASDIfCiX3qQDMMHfpAM4QUABWAFqA1dHQXIHQUxBV1YyRxIKCAEQARgBKgJXThgBIgQIARABKAIoAygEMAE)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $488 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:487.30&airProductToken=AQqRAQotCNecARIDMjI2GMh8IMFFKJG4pAMw4bikAzhKQABYAWoDV0dBcgdKWEFWUzJHCi8I15wBEgQ0MDIxGMFFIOywASicu6QDMIe9pAM4SkABWAFqA1dHQXIHSlhBVlMyRwovCNecARIENDEwNhjssAEgw2Qo4b2kAzC2vqQDOEpAAVgBagNXR0FyB0pYQVZTMkcKkAEKLgjXnAESBDE3NjEYw2QgoQMo6tikAzDT2aQDOEFAAFgBagNXR0FyB0FMQVdWMkcKLQjXnAESAjkwGKEDIKOaASj626QDMIHdpAM4QUABWAFqA1dHQXIHQUxBV1YyRwovCNecARIEMzM1NBijmgEgyHwol96kAzDB36QDOEFAAVgBagNXR0FyB0FMQVdWMkcSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $492 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:492.00&airProductToken=AQqSAQouCNecARIEMTI2MhjIfCDzAyi8t6QDMPW4pAM4SkAAWAFqA1dHQXIHSlhBVlMyRwovCNecARIEMTY2NRjzAyDssAEonbmkAzDHuqQDOEpAAVgBagNXR0FyB0pYQVZTMkcKLwjXnAESBDQxMDYY7LABIMNkKOG9pAMwtr6kAzhKQAFYAWoDV0dBcgdKWEFWUzJHCpABCi4I15wBEgQxNjI3GMNkIINpKK7YpAMwq9mkAzhGQABYAWoDV0dBcgdGTEFWUDJHCi4I15wBEgQxNDkxGINpIMFFKNrapAMwp9ykAzhGQAFYAWoDV0dBcgdGTEFWUDJHCi4I15wBEgQxOTQwGMFFIMh8KLLfpAMw%5Fd-kAzhGQAFYAWoDV0dBcgdGTEFWUDJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Jan 8 from Islip to Des Moines, returning Mon, Jan 11, priced at $493 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:1/8/2027TANYT&leg2=from:DSM,to:ISP,departure:1/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:492.60&airProductToken=AQqQAQotCNecARIDODQ5GMh8IMFFKOX6oQMwv%5FuhAzhBQABYAWoDV0dBcgdBTEFXVjJHCi4I15wBEgMzOTIYwUUg7LABKLn9oQMwwv-hAzhBQAFYAWoDV0dBcgdBTEFXVjJHCi8I15wBEgQ0MTA2GOywASDDZCiCgqIDMNeCogM4QUABWAFqA1dHQXIHQUxBV1YyRwqOAQouCNecARIEMTc2MRjDZCChAyiInqIDMOKeogM4SkAAWAFqA1dHQXIHSlhBVlMyRwotCNecARIDNjQ4GKEDIMFFKLmgogMw8qGiAzhKQAFYAWoDV0dBcgdKWEFWUzJHCi0I15wBEgM4OTQYwUUgyHwosKOiAzD7o6IDOEpAAVgBagNXR0FyB0pYQVZTMkcSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB)

Fri, Jan 8 - Mon, Jan 11 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $497 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:497.00&airProductToken=AQqOAQotCNecARIDMjI2GMh8IMFFKJG4pAMw4bikAzhBQABYAWoDV0dBcgdBTEFXVjJHCi0I15wBEgM4NjQYwUUgg2ko1LmkAzDOu6QDOEFAAVgBagNXR0FyB0FMQVdWMkcKLgjXnAESBDI5MjYYg2kgw2Qo-LykAzDhvaQDOEFAAVgBagNXR0FyB0FMQVdWMkcKkAEKLgjXnAESBDE2MjkYw2Qgg2kopt6kAzCZ36QDOEFAAFgBagNXR0FyB0FMQVdWMkcKLgjXnAESBDE1MTUYg2kgzHAomOGkAzDq4qQDOEFAAVgBagNXR0FyB0FMQVdWMkcKLgjXnAESBDE5OTEYzHAgyHwo3OWkAzD35qQDOEFAAVgBagNXR0FyB0FMQVdWMkcSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $498 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:497.60&airProductToken=AQqOAQotCNecARIDODQ5GMh8IMFFKO-1pAMwybakAzhGQABYAWoDV0dBcgdGTEFWUDJHCi0I15wBEgMzNzIYwUUgg2kovLekAzCsuaQDOEZAAVgBagNXR0FyB0ZMQVZQMkcKLgjXnAESBDI5MjYYg2kgw2Qo-LykAzDhvaQDOEZAAVgBagNXR0FyB0ZMQVZQMkcSCggBEAEYASoCV04YASIECAEQASgCKAMoBDAB)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

[Select Southwest Airlines flight, departing Fri, Feb 5 from Islip to Des Moines, returning Mon, Feb 8, priced at $503 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:DSM,departure:2/5/2027TANYT&leg2=from:DSM,to:ISP,departure:2/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:502.30&airProductToken=AQqSAQouCNecARIEMTk2NxjIfCDMcCiiuaQDMNG6pAM4QUAAWAFqA1dHQXIHQUxBV1YyRwovCNecARIEMjU0NhjMcCDssAEoiLukAzC8vKQDOEFAAVgBagNXR0FyB0FMQVdWMkcKLwjXnAESBDQxMDYY7LABIMNkKOG9pAMwtr6kAzhBQAFYAWoDV0dBcgdBTEFXVjJHCpABCi4I15wBEgQxNzYxGMNkIKEDKOrYpAMw09mkAzhBQABYAWoDV0dBcgdBTEFXVjJHCi4I15wBEgQ0MzA5GKEDIMFFKIDapAMw3NukAzhBQAFYAWoDV0dBcgdBTEFXVjJHCi4I15wBEgQxOTQwGMFFIMh8KLLfpAMw%5Fd-kAzhBQAFYAWoDV0dBcgdBTEFXVjJHEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ)

Fri, Feb 5 - Mon, Feb 8 · ISP · DSM · Roundtrip

## Book with confidence

### Islip to Des Moines Flights

#### The cheapest times to fly from Islip to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Des Moines are during the month of February. You can find some of the cheapest flights from Islip to Des Moines with Expedia's search tool and vast selection of airlines.

#### The best time to book a flight from Islip to Des Moines

Sunday is one of the best days to book for cheap flights from Islip to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

#### How to find cheap round-trip tickets from Islip to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Des Moines in 2026\. You can also book with separate airlines for your outbound and return journeys, from $234 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Islip to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*\*Terms apply.*

*Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.*

## Frequently Asked Questions

### How much does a flight from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) cost?

You can find cheap one-way flights from $234 and cheap return flights $467 ISP to DSM with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when ISP to DSM ticket fares go up or down.

### What is the cheapest month to fly from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

The cheapest month to fly from ISP to DSM is February when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.

### Which airlines fly direct from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

Enter ISP to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

### How do I find cheap flights from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

To find a cheap flight from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down.

### What is the best time to fly from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.

### What is the earliest flight from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from ISP to DSM. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.

### How long does it take to fly from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

Flights from ISP to DSM with one stop typically take around 14 hours 50 minutes, covering approximately 1,068 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

### Can you fly business or first class from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

Select the "Business class" and "First class" filters when looking for ISP to DSM flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.

### How do I earn miles on a Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?

It's easy to earn miles on a Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia.

\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

### Is it cheaper to buy a plane ticket from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?

Typically, booking a last minute flight from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

### Is it cheaper to book a Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?

Securing a Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) [Des Moines Vacation Packages](https://www.expedia.com/des-moines.d601690.destination-travel-guides) is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

### Can I cancel or change the date of my flight from Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.)?

If you booked your Islip, NY (ISP-MacArthur) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information.

## Travel information

| Origin airport      | MacArthur Airport                |
| ------------------- | -------------------------------- |
| Destination airport | Des Moines International Airport |
| Distance            | 1,067 miles away                 |
| Roundtrip price     | $467                             |

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- [Flights from Portland (PWM) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pwm/dsm/portland-to-des-moines)
- [Flights from Rochester (ROC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/roc/dsm/rochester-to-des-moines)
- [Flights from West Palm Beach (PBI) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pbi/dsm/west-palm-beach-to-des-moines)
- [Flights from Fort Lauderdale (FLL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/fll/dsm/fort-lauderdale-to-des-moines)
- [Flights from New York (NYC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/nyc/dsm/new-york-to-des-moines)
- [Flights from Sacramento (SMF) to Des Moines (DSM)](https://www.expedia.com/lp/flights/smf/dsm/sacramento-to-des-moines)
- [Flights from Omaha (OMA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/oma/dsm/omaha-to-des-moines)
- [Flights from Minneapolis (MSP) to Des Moines (DSM)](https://www.expedia.com/lp/flights/msp/dsm/minneapolis-to-des-moines)
- [Flights from Newark Liberty Intl. Airport (EWR) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ewr/dsm/newark-liberty-intl-airport-to-des-moines)
- [Flights from Fort Myers (RSW) to Des Moines (DSM)](https://www.expedia.com/lp/flights/rsw/dsm/fort-myers-to-des-moines)
- [Flights from San Diego (SAN) to Des Moines (DSM)](https://www.expedia.com/lp/flights/san/dsm/san-diego-to-des-moines)
- [Flights from Washington (IAD) to Des Moines (DSM)](https://www.expedia.com/lp/flights/iad/dsm/washington-to-des-moines)
- [Flights from Burlington (BTV) to Des Moines (DSM)](https://www.expedia.com/lp/flights/btv/dsm/burlington-to-des-moines)
- [Flights from Cedar Rapids (CID) to Des Moines (DSM)](https://www.expedia.com/lp/flights/cid/dsm/cedar-rapids-to-des-moines)
- [Flights from Honolulu (HNL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/hnl/dsm/honolulu-to-des-moines)
- [Flights from Billings (BIL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/bil/dsm/billings-to-des-moines)
- [Flights from Pensacola (PNS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pns/dsm/pensacola-to-des-moines)
- [Flights from Spokane (GEG) to Des Moines (DSM)](https://www.expedia.com/lp/flights/geg/dsm/spokane-to-des-moines)
- [Flights from Harrisburg (MDT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mdt/dsm/harrisburg-to-des-moines)
- [Flights from Greenville (GSP) to Des Moines (DSM)](https://www.expedia.com/lp/flights/gsp/dsm/greenville-to-des-moines)
- [Flights from Los Angeles (LAX) to Des Moines (DSM)](https://www.expedia.com/lp/flights/lax/dsm/los-angeles-to-des-moines)
- [Flights from Albuquerque (ABQ) to Des Moines (DSM)](https://www.expedia.com/lp/flights/abq/dsm/albuquerque-to-des-moines)
- [Flights from Ontario Intl. Airport (ONT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ont/dsm/ontario-to-des-moines)
- [Flights from San Antonio (SAT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sat/dsm/san-antonio-to-des-moines)
- [Flights from Tucson (TUS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/tus/dsm/tucson-to-des-moines)
- [Flights from Atlanta (ATL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/atl/dsm/atlanta-to-des-moines)
- [Flights from Kansas City (MCI) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mci/dsm/kansas-city-to-des-moines)
- [Flights from Charlotte (CLT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/clt/dsm/charlotte-to-des-moines)
- [Flights from Grand Rapids (GRR) to Des Moines (DSM)](https://www.expedia.com/lp/flights/grr/dsm/grand-rapids-to-des-moines)
- [Flights from Colorado Springs (COS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/cos/dsm/colorado-springs-to-des-moines)
- [Flights from Austin (AUS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/aus/dsm/austin-to-des-moines)
- [Flights from Eugene (EUG) to Des Moines (DSM)](https://www.expedia.com/lp/flights/eug/dsm/eugene-to-des-moines)
- [Flights from Houston (HOU) to Des Moines (DSM)](https://www.expedia.com/lp/flights/hou/dsm/houston-to-des-moines)
- [Flights from Philadelphia (PHL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/phl/dsm/philadelphia-to-des-moines)
- [Flights from Hartford (BDL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/bdl/dsm/hartford-to-des-moines)
- [Flights from Albany (ALB) to Des Moines (DSM)](https://www.expedia.com/lp/flights/alb/dsm/albany-to-des-moines)
- [Flights from Denver (DEN) to Des Moines (DSM)](https://www.expedia.com/lp/flights/den/dsm/denver-to-des-moines)
- [Flights from Rapid City (RAP) to Des Moines (DSM)](https://www.expedia.com/lp/flights/rap/dsm/rapid-city-to-des-moines)
- [Flights from Las Vegas (LAS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/las/dsm/las-vegas-to-des-moines)
- [Flights from Madison (MSN) to Des Moines (DSM)](https://www.expedia.com/lp/flights/msn/dsm/madison-to-des-moines)
- [Flights from New Orleans (MSY) to Des Moines (DSM)](https://www.expedia.com/lp/flights/msy/dsm/new-orleans-to-des-moines)
- [Flights from Phoenix (PHX) to Des Moines (DSM)](https://www.expedia.com/lp/flights/phx/dsm/phoenix-to-des-moines)
- [Flights from Nairobi (NBO) to Des Moines (DSM)](https://www.expedia.com/lp/flights/nbo/dsm/nairobi-to-des-moines)
- [Flights from Raleigh (RDU) to Des Moines (DSM)](https://www.expedia.com/lp/flights/rdu/dsm/raleigh-to-des-moines)
- [Flights from Davenport (DVN) to Des Moines (DSM)](https://www.expedia.com/lp/flights/dvn/dsm/davenport-to-des-moines)
- [Flights from McAllen (MFE) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mfe/dsm/mcallen-to-des-moines)
- [Flights from Boston (BOS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/bos/dsm/boston-to-des-moines)
- [Flights from Little Rock (LIT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/lit/dsm/little-rock-to-des-moines)
- [Flights from Birmingham (BHM) to Des Moines (DSM)](https://www.expedia.com/lp/flights/bhm/dsm/birmingham-to-des-moines)
- [Flights from Chicago (ORD) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ord/dsm/chicago-to-des-moines)
- [Flights from Baltimore (BWI) to Des Moines (DSM)](https://www.expedia.com/lp/flights/bwi/dsm/baltimore-to-des-moines)
- [Flights from Fresno (FAT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/fat/dsm/fresno-to-des-moines)
- [Flights from Providence (PVD) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pvd/dsm/providence-to-des-moines)
- [Flights from Tulsa (TUL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/tul/dsm/tulsa-to-des-moines)
- [Flights from Milwaukee (MKE) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mke/dsm/milwaukee-to-des-moines)
- [Flights from Dallas (DFW) to Des Moines (DSM)](https://www.expedia.com/lp/flights/dfw/dsm/dallas-to-des-moines)
- [Flights from Sioux City (SUX) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sux/dsm/sioux-city-to-des-moines)
- [Flights from Norfolk (ORF) to Des Moines (DSM)](https://www.expedia.com/lp/flights/orf/dsm/norfolk-to-des-moines)
- [Flights from St. Louis (STL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/stl/dsm/st-louis-to-des-moines)
- [Flights from Oklahoma City (OKC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/okc/dsm/oklahoma-city-to-des-moines)
- [Flights from Boise (BOI) to Des Moines (DSM)](https://www.expedia.com/lp/flights/boi/dsm/boise-to-des-moines)
- [Flights from Knoxville (TYS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/tys/dsm/knoxville-to-des-moines)
- [Flights from Portland (PDX) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pdx/dsm/portland-to-des-moines)
- [Flights from Orlando (MCO) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mco/dsm/orlando-to-des-moines)
- [Flights from Houston (IAH) to Des Moines (DSM)](https://www.expedia.com/lp/flights/iah/dsm/houston-to-des-moines)
- [Flights from Lagos (LOS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/los/dsm/lagos-to-des-moines)
- [Flights from Louisville (SDF) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sdf/dsm/louisville-to-des-moines)
- [Flights from San Francisco (SFO) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sfo/dsm/san-francisco-to-des-moines)
- [Flights from Miami (MIA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mia/dsm/miami-to-des-moines)
- [Flights from Richmond (RIC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ric/dsm/richmond-to-des-moines)
- [Flights from Springfield (SGF) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sgf/dsm/springfield-to-des-moines)
- [Flights from Wichita (ICT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ict/dsm/wichita-to-des-moines)
- [Flights from Columbus (CMH) to Des Moines (DSM)](https://www.expedia.com/lp/flights/cmh/dsm/columbus-to-des-moines)
- [Flights from Cincinnati (CVG) to Des Moines (DSM)](https://www.expedia.com/lp/flights/cvg/dsm/cincinnati-to-des-moines)
- [Flights from Seoul (ICN) to Des Moines (DSM)](https://www.expedia.com/lp/flights/icn/dsm/seoul-to-des-moines)
- [Flights from Cleveland (CLE) to Des Moines (DSM)](https://www.expedia.com/lp/flights/cle/dsm/cleveland-to-des-moines)
- [Flights from Salt Lake City (SLC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/slc/dsm/salt-lake-city-to-des-moines)
- [Flights from Charleston (CHS) to Des Moines (DSM)](https://www.expedia.com/lp/flights/chs/dsm/charleston-to-des-moines)
- [Flights from Indianapolis (IND) to Des Moines (DSM)](https://www.expedia.com/lp/flights/ind/dsm/indianapolis-to-des-moines)
- [Flights from New York (JFK) to Des Moines (DSM)](https://www.expedia.com/lp/flights/jfk/dsm/new-york-to-des-moines)
- [Flights from Iowa City (IOW) to Des Moines (DSM)](https://www.expedia.com/lp/flights/iow/dsm/iowa-city-to-des-moines)
- [Flights from Detroit (DTW) to Des Moines (DSM)](https://www.expedia.com/lp/flights/dtw/dsm/detroit-to-des-moines)
- [Flights from Manila (MNL) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mnl/dsm/manila-to-des-moines)
- [Flights from Memphis (MEM) to Des Moines (DSM)](https://www.expedia.com/lp/flights/mem/dsm/memphis-to-des-moines)
- [Flights from San Jose (SJC) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sjc/dsm/san-jose-to-des-moines)
- [Flights from Lincoln (LNK) to Des Moines (DSM)](https://www.expedia.com/lp/flights/lnk/dsm/lincoln-to-des-moines)
- [Flights from Orange County (SNA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sna/dsm/orange-county-to-des-moines)
- [Flights from Syracuse (SYR) to Des Moines (DSM)](https://www.expedia.com/lp/flights/syr/dsm/syracuse-to-des-moines)
- [Flights from Washington (DCA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/dca/dsm/washington-to-des-moines)
- [Flights from Tampa (TPA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/tpa/dsm/tampa-to-des-moines)
- [Flights from Fargo (FAR) to Des Moines (DSM)](https://www.expedia.com/lp/flights/far/dsm/fargo-to-des-moines)
- [Flights from Appleton (ATW) to Des Moines (DSM)](https://www.expedia.com/lp/flights/atw/dsm/appleton-to-des-moines)
- [Flights from New York (LGA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/lga/dsm/new-york-to-des-moines)
- [Flights from Jacksonville (JAX) to Des Moines (DSM)](https://www.expedia.com/lp/flights/jax/dsm/jacksonville-to-des-moines)
- [Flights from Buffalo (BUF) to Des Moines (DSM)](https://www.expedia.com/lp/flights/buf/dsm/buffalo-to-des-moines)
- [Flights from Seattle (SEA) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sea/dsm/seattle-to-des-moines)
- [Flights from Pittsburgh (PIT) to Des Moines (DSM)](https://www.expedia.com/lp/flights/pit/dsm/pittsburgh-to-des-moines)
- [Flights from San Juan (SJU) to Des Moines (DSM)](https://www.expedia.com/lp/flights/sju/dsm/san-juan-to-des-moines)

\*Available to One Key members.

## Other language versions

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hreflang:
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  es: https://www.expedia.com/es/lp/vuelos/isp/dsm/islip-a-des-moines
  ar: https://www.expedia.sa/lp/flights/isp/dsm/islip-to-des-moines
  nb-NO: https://www.expedia.no/lp/fly/isp/dsm/islip-til-des-moines
  id-ID: https://www.expedia.co.id/lp/flights/isp/dsm/islip-to-des-moines
  en-US: https://www.expedia.com/lp/flights/isp/dsm/islip-to-des-moines
```